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Can promote mitochondrial permeability transition and facilitate necrotic cell death under different types of stress conditions. Additionally we are shipping Heme Binding Protein 2 Proteins (6) and many more products for this protein.
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The gene copy numbers and mRNA levels for both ALG-2 (show PDCD6 Antibodies) and HEBP2 are significantly upregulated in breast and lung cancer. Coexpression of ALG-2 (show PDCD6 Antibodies) and HEBP2 markedly increases the cytoplasmic pool of ALG-2 (show PDCD6 Antibodies) and alters the subcellular distribution of HEBP2. Abnormalities in the ALG-2 (show PDCD6 Antibodies)/HEBP2 interaction impairs spindle orientation and positioning during mitosis.
There are important structural differences in the BH3 domain in the intact SOUL molecule and the same sequence bound to Bcl-xL (show BCL2L1 Antibodies).
The heme-binding properties and coordination structure of SOUL protein are distinct from those of mouse liver p22HBP (show HEBP1 Antibodies), despite high sequence homology.
Can promote mitochondrial permeability transition and facilitate necrotic cell death under different types of stress conditions. Does not bind hemin (By similarity). May have low affinity for heme.
heme-binding protein 2
, heme binding protein 2
, heme-binding protein 2-like
, SOUL/heme-binding protein
, placental protein 23
, putative heme-binding protein