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Heparan Sulfate 2-O-Sulfotransferase 1 Proteins (HS2ST1)

Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. Additionally we are shipping HS2ST1 Antibodies (53) and HS2ST1 Kits (7) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HS2ST1 9653 Q7LGA3
HS2ST1 23908 Q8R3H7
Rat HS2ST1 HS2ST1 292155  
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Top HS2ST1 Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

HS2ST1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine) ,
,

More Proteins for Heparan Sulfate 2-O-Sulfotransferase 1 (HS2ST1) Interaction Partners

Human Heparan Sulfate 2-O-Sulfotransferase 1 (HS2ST1) interaction partners

  1. C5-epimerase and 2-O-sulfotransferase in association generate extended domains of consecutive GlcNS-IdoA2S Sequence.

  2. analysis of differences and similarities various residues play in the biological roles of the HS-2OST and CS-2OST enzymes

Mouse (Murine) Heparan Sulfate 2-O-Sulfotransferase 1 (HS2ST1) interaction partners

  1. Inactivation of uronyl 2-O-sulfotransferase in endothelial cells (Hs2st), an enzyme that acts downstream from Ndst1 (show NDST1 Proteins), results in enhanced neutrophil recruitment in several models of acute inflammation.

  2. The phenotype of Hs2st(-/-) mutant kidneys suggests that signalling between two tissues, ureteric bud and metanephric mesenchyme, is disrupted.

  3. mice homozygous for a null mutation in Hs2st indicated reduction in the thickness of the embryonic cerebral cortex; critical role for 2-O-sulphation of heparan sulphate proteoglycan (show GPC3 Proteins) in regulating cell proliferation during cerebral cortex development

  4. Hs2st and/or Hs6st1 expression coincides with Slit expression domains at locations where retinal ganglion cell(RGC) axons make navigation errors in Hs2st-/- and Hs6st1-/- mutants, and Hs6st1-/-RGC axons are less sensitive to Slit2 repulsion.

Zebrafish Heparan Sulfate 2-O-Sulfotransferase 1 (HS2ST1) interaction partners

  1. Prmt7 regulates epiboly by facilitating 2-OST and modulating actin cytoskeleton

  2. 2-OST functions within the Wnt (show WNT2 Proteins) pathway, downstream of Wnt (show WNT2 Proteins) ligand signaling and upstream of Gsk3beta and beta-catenin (show CTNNB1 Proteins) intracellular localization and function

  3. 2-O-sulfotransferase (2-OST) catalyzes the transfer of sulfate groups to the 2-O position of uronic acid residues of heparan sulfate.

HS2ST1 Protein Profile

Protein Summary

Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. This gene encodes a member of the heparan sulfate biosynthetic enzyme family that transfers sulfate to the 2 position of the iduronic acid residue of heparan sulfate. The disruption of this gene resulted in no kidney formation in knockout embryonic mice, indicating that the absence of this enzyme may interfere with the signaling required for kidney formation. Two alternatively spliced transcript variants that encode different proteins have been found for this gene.

Gene names and symbols associated with HS2ST1

  • heparan sulfate 2-O-sulfotransferase 1 (HS2ST1)
  • heparan sulfate 2-O-sulfotransferase 1 (Tsp_05909)
  • heparan sulfate 2-O-sulfotransferase 1 (hs2st1)
  • heparan sulfate 2-O-sulfotransferase 1 (LOC100228316)
  • Heparan sulfate 2-O-sulfotransferase 1 (hs2st)
  • heparan sulfate 2-O-sulfotransferase 1 (Hs2st1)
  • heparan sulfate 2-O-sulfotransferase 1a (hs2st1a)
  • 2-OST protein
  • 2OST protein
  • AW214369 protein
  • CHS2ST protein
  • dJ604K5.2 protein
  • HS2st protein
  • hs2st1 protein
  • im:7147474 protein
  • mKIAA0448 protein
  • zgc:158230 protein

Protein level used designations for HS2ST1

heparan sulfate 2-O-sulfotransferase 1 , heparan sulfate 2-O-sulfotransferase 1-like , Heparan sulfate 2-O-sulfotransferase 1 , 2-O-sulfotransferase , 2OST , 2-OST , heparan sulfate 2-sulfotransferase

GENE ID SPECIES
100352170 Oryctolagus cuniculus
100388469 Callithrix jacchus
469374 Pan troglodytes
479963 Canis lupus familiaris
712540 Macaca mulatta
10911060 Trichinella spiralis
100010181 Monodelphis domestica
100145562 Xenopus (Silurana) tropicalis
100156232 Sus scrofa
100228316 Taeniopygia guttata
100380444 Salmo salar
100464822 Ailuropoda melanoleuca
9653 Homo sapiens
23908 Mus musculus
292155 Rattus norvegicus
399095 Xenopus laevis
395140 Gallus gallus
523780 Bos taurus
100173485 Pongo abelii
791188 Danio rerio
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