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Heparan Sulfate 6-O-Sulfotransferase 2 Proteins (HS6ST2)

Heparan sulfate proteoglycans are ubiquitous components of the cell surface, extracellular matrix, and basement membranes, and interact with various ligands to influence cell growth, differentiation, adhesion, and migration. Additionally we are shipping HS6ST2 Kits (18) and HS6ST2 Antibodies (6) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HS6ST2 50786 Q80UW0
Rat HS6ST2 HS6ST2 302489  
HS6ST2 90161 Q96MM7
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Top HS6ST2 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details

HS6ST2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
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Human ,
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More Proteins for Heparan Sulfate 6-O-Sulfotransferase 2 (HS6ST2) Interaction Partners

Mouse (Murine) Heparan Sulfate 6-O-Sulfotransferase 2 (HS6ST2) interaction partners

  1. Overexpression or silencing of HS6ST2 significantly enhanced or abrogated the effects of fibroblast growth factor (FGF)2 (show FGF2 Proteins) on chondrocyte growth, respectively.

  2. Hs6st2 knockout mice had increased body weight, insulin (show INS Proteins) resistance and high thyroid hormone (show PTH Proteins) level.

  3. both HS6ST-1 (show HS6ST1 Proteins) and HS6ST-2 are involved in 6-O-sulfation of heparin and that the proper packaging and storage of tryptase (show TPSAB1 Proteins)

  4. Results indicate that HS6ST2 gene influences expression of genes linked to aggrecan (show ACAN Proteins) metabolism and is implicated in pathogenesis of osteoarthritis.

  5. 6OST2 is more mesenchymal than its isoenzymes during development

  6. Data show that high expression of 6-O-sulfotransferase (6-OST)-1, 2, or 3 resulted in increased 6-O-sulfation of N-sulfated (show SULF1 Proteins) and N-acetylated glucosamine units, and in altered heparan sulfate domain structure.

Human Heparan Sulfate 6-O-Sulfotransferase 2 (HS6ST2) interaction partners

  1. HS6ST-1 (show HS6ST1 Proteins) and HS6ST-2 have roles in regulating the angiogenic program in ovarian cancer cells affecting HB-EGF (show HBEGF Proteins) signaling and subsequent expression of angiogenic cytokines by cancer cells

  2. HS6ST2 knockdown disrupts epithelial-mesenchymal transition and suggesets that HS6ST2 potentiates Notch (show NOTCH1 Proteins) signaling in pancreatic cancer cells.

  3. we have characterized HS6ST-2 and HS6ST-1 (show HS6ST1 Proteins) human isologues, including their chromosomal localizations,HS6STs could also transfer sulfate to N -sulfoglucosamine residues located at the non-reducing terminal of HS with high affinity.

Zebrafish Heparan Sulfate 6-O-Sulfotransferase 2 (HS6ST2) interaction partners

  1. hs6st2 is required for the branching morphogenesis of the caudal vein during embryonic development.

HS6ST2 Protein Profile

Protein Summary

Heparan sulfate proteoglycans are ubiquitous components of the cell surface, extracellular matrix, and basement membranes, and interact with various ligands to influence cell growth, differentiation, adhesion, and migration. This gene encodes a member of the heparan sulfate (HS) sulfotransferase gene family, which catalyze the transfer of sulfate to HS. Different family members and isoforms are thought to synthesize heparan sulfates with tissue-specific structures and functions. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with HS6ST2

  • heparan sulfate 6-O-sulfotransferase 2 (HS6ST2)
  • heparan sulfate 6-O-sulfotransferase 2 (Hs6st2)
  • heparan sulfate 6-O-sulfotransferase 2 (hs6st2)
  • 6OST2 protein
  • fb80f12 protein
  • hs6st protein
  • HS6ST-2 protein
  • RGD1563872 protein
  • RGD1564397 protein
  • wu:fb80f12 protein

Protein level used designations for HS6ST2

heparan sulfate 6-O-sulfotransferase 2 , heparan-sulfate 6-O-sulfotransferase 2 , heparan-sulfate 6-O-sulfotransferase 2-like , HS6ST-2 , mHS6ST-2 , cHS6ST-2 , heparan sulfate 6-O-sulfotransferase-2 , HS 6-OST-2

GENE ID SPECIES
473786 Pan troglodytes
492142 Canis lupus familiaris
517768 Bos taurus
100054266 Equus caballus
100351196 Oryctolagus cuniculus
100398118 Callithrix jacchus
100439955 Pongo abelii
50786 Mus musculus
302489 Rattus norvegicus
90161 Homo sapiens
395150 Gallus gallus
378450 Danio rerio
101110034 Ovis aries
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