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Heparan sulfate (HS) sulfotransferases, such as HS6ST3, modify HS to generate structures required for interactions between HS and a variety of proteins. Additionally we are shipping Heparan Sulfate 6-O-Sulfotransferase 3 Kits (16) and Heparan Sulfate 6-O-Sulfotransferase 3 Antibodies (8) and many more products for this protein.
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Silencing HS6ST3 diminished tumor cell growth and progression in breast cancer cells. Silencing HS6ST3 down-regulated IGF1R (show IGF1R Proteins) and up-regulated XAF1 (show XAF1 Proteins).
Single-nucleotide polymorphisms within the HS6ST3 gene are associated with obesity and triglyceride levels. [Meta-analysis]
6OST3 appears at later stages and in a more restricted manner than its isoenzymes during development
Data show that high expression of 6-O-sulfotransferase (6-OST)-1, 2, or 3 resulted in increased 6-O-sulfation of N-sulfated (show SULF1 Proteins) and N-acetylated glucosamine units, and in altered heparan sulfate domain structure.
Heparan sulfate (HS) sulfotransferases, such as HS6ST3, modify HS to generate structures required for interactions between HS and a variety of proteins. These interactions are implicated in proliferation and differentiation, adhesion, migration, inflammation, blood coagulation, and other diverse processes (Habuchi et al., 2000
heparan sulfate 6-O-sulfotransferase 3
, heparan-sulfate 6-O-sulfotransferase 3
, HS 6-OST-3