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anti-Heparanase 2 (HPSE2) Antibodies

HPSE2 encodes a heparanase enzyme. Additionally we are shipping and Heparanase 2 Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HPSE2 60495 Q8WWQ2
HPSE2 545291  
HPSE2 368128  
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Top anti-Heparanase 2 Antibodies at antibodies-online.com

Showing 10 out of 81 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-HPSE2 AntibodyTitration: 1.0 µg/mL  Positive Control: Jurkat Whole Cell 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB HPSE2 Antibody (C-term) (ABIN656918) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue reacted with Heparanase-2 / HPA2 Antibody (C-term) followed by peroxidase conjugation of the secondary antibody and DAB staining. Western blot analysis of Heparanase-2 / HPA2 Antibody (C-term) in CEM cell line lysates (35ug/lane). This demonstrates the HPSE2 antibody detected the HPSE2 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated ICC, FACS, IHC (fro), IF, IHC, WB 0.1 mL Log in to see 5 to 7 Days
$408.19
Details
Human Rabbit Un-conjugated IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded human lung adenocarcinoma , using HPSE2, antibody at 1:100 dilution. IHC-P Image Immunohistochemical analysis of paraffin-embedded human uterus, using HPA2, antibody(10 μg/ml). 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated IHC (p), WB Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IHC (p), WB Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of HPA2 staining in human prostate formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the Western blot analysis of HPA2 expression in Hela (A), SKOV3 (B), mouse brain (C), rat brain (D) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit APC IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: HPSE2 Antibody [NBP1-93691] - Staining of human cell line U-2 OS shows positivity in nucleus but not nucleoli & cytoplasm. Western Blot: HPSE2 Antibody [NBP1-93691] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp.Lane 4: Human plasma (IgG/HSA depleted) 0.1 mL Log in to see 8 to 11 Days
$439.69
Details

HPSE2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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More Antibodies against Heparanase 2 Interaction Partners

Pig (Porcine) Heparanase 2 (HPSE2) interaction partners

  1. study of tissue expression profiles, polymorphisms of HPSE (show HPSE Antibodies) and HPSE2 genes and changes of their mRNA levels in porcine alveolar macrophages (PAMs) induced by PRRSV; upon stimulation in healthy piglets with PRRSV, HPSE (show HPSE Antibodies) mRNA was obviously upregulated, while HPSE2 mRNA did not induce a prominent change in PAMs

Human Heparanase 2 (HPSE2) interaction partners

  1. HPSE2 mutations were found in one Urofacial syndrome family but not detected in patients with non-neurogenic neurogenic bladder and severe lower urinary tract dysfunction

  2. Heparanase 2 is more intensely expressed in the glandular tissue of cancer than in nonneoplastic endometrium; the HPSE2 expression in the stromal tissue is higher in the nonneoplastic controls compared with cancer mainly in the secretory endometrium.

  3. High expression of heparanase-2 is associated significantly with gastric tumor growth and differentiation

  4. Data indicate that the overexpression of HPSE1 (show HPSE Antibodies) and HPSE2 in the intervertebral degenerated discs suggests a role for these factors in mediating extracellular matrix remodeling in degenerative discs during disease development.

  5. HPSE2 c.631T>C (p.Y211H) is a novel benign SNP and c.1628A>T (p.N543I) is the disease-causing mutation in urofacial syndrome.

  6. Studies indicate that cathepsin L (show CTSL1 Antibodies) as the heparanase (show HPSE Antibodies) activating protease.

  7. These results indicate a regulatory effect of heparanase (show HPSE Antibodies) on TFPI (show TFPI Antibodies) and TFPI-2 (show TFPI2 Antibodies) in trophoblasts, suggesting a potential involvement of heparanase (show HPSE Antibodies) in early miscarriages.

  8. We now report evidence that Heparanse 2 (HPSE2) is the culprit gene for the syndrome. Mutations with a loss of function in the Heparanase 2 (HPSE2) gene

  9. Homozygous exonic deletions, nonsense mutations, and frameshift mutations in five further unrelated families confirmed HPSE2 as the causative gene for UFS

  10. Results demonstrated that the effectors from heparanase peptide-immunized mice could effectively lyse various tumor cells that were heparanase positive and HLA-A*0201 matched.

Mouse (Murine) Heparanase 2 (HPSE2) interaction partners

  1. Deletion of Hpse2 cause the urofacial syndrome-like phenotype in mice.

Heparanase 2 (HPSE2) Antigen Profile

Protein Summary

This gene encodes a heparanase enzyme. The encoded protein is a endoglycosidase that degrades heparin sulfate proteoglycans located on the extracellular matrix and cell surface. This protein may be involved in biological processes involving remodeling of the extracellular matrix including angiogenesis and tumor progression. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with anti-Heparanase 2 (HPSE2) Antibodies

  • heparanase 2 (HPSE2) antibody
  • heparanase 2 (hpse2) antibody
  • heparanase 2 (Hpse2) antibody
  • Gm968 antibody
  • Hpa2 antibody
  • HPR2 antibody
  • si:dkeyp-22h2.2 antibody
  • UFS antibody
  • UFS1 antibody

Protein level used designations for anti-Heparanase 2 (HPSE2) Antibodies

heparanase 2 , heparanase 3 , heparanase-like protein , inactive heparanase-2 , heparanase-2

GENE ID SPECIES
486831 Canis lupus familiaris
537343 Bos taurus
100070602 Equus caballus
100157983 Sus scrofa
423834 Gallus gallus
466176 Pan troglodytes
562573 Danio rerio
100020982 Monodelphis domestica
100407598 Callithrix jacchus
60495 Homo sapiens
545291 Mus musculus
368128 Rattus norvegicus
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