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The protein encoded by HAVCR1 is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. Additionally we are shipping HAVCR1 Kits (64) and HAVCR1 Proteins (35) and many more products for this protein.
Showing 10 out of 147 products:
Human Monoclonal HAVCR1 Primary Antibody for FACS, IHC - ABIN4899579
Ivie, Fennessey, Sheng, Rubin, McClain: Gene-trap mutagenesis identifies mammalian genes contributing to intoxication by Clostridium perfringens ε-toxin. in PLoS ONE 2011
Show all 4 references for ABIN4899579
Human Polyclonal HAVCR1 Primary Antibody for WB - ABIN318766
Meyers, Sabatos, Chakravarti, Kuchroo: The TIM gene family regulates autoimmune and allergic diseases. in Trends in molecular medicine 2005
Show all 2 references for ABIN318766
Human Polyclonal HAVCR1 Primary Antibody for EIA, IHC (p) - ABIN500911
Feigelstock, Thompson, Mattoo, Zhang, Kaplan: The human homolog of HAVcr-1 codes for a hepatitis A virus cellular receptor. in Journal of virology 1998
Mouse (Murine) Polyclonal HAVCR1 Primary Antibody for ICC, IHC (fro) - ABIN1077715
Schindler, Bondeva, Schindler, Claus, Franke, Wolf: Preconditioned suppression of prolyl-hydroxylases attenuates renal injury but increases mortality in septic murine models. in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2016
Human Polyclonal HAVCR1 Primary Antibody for WB - ABIN657951
Fontaine-Bisson, Renström, Rolandsson, , Payne, Hallmans, Barroso, Franks: Evaluating the discriminative power of multi-trait genetic risk scores for type 2 diabetes in a northern Swedish population. in Diabetologia 2010
Human Polyclonal HAVCR1 Primary Antibody for WB - ABIN2782775
de Souza, Oak, Jordanhazy, DeKruyff, Fruman, Kane: T cell Ig and mucin domain-1-mediated T cell activation requires recruitment and activation of phosphoinositide 3-kinase. in Journal of immunology (Baltimore, Md. : 1950) 2008
Data suggest that T-cell immunoglobulin domain and mucin (show SLC13A2 Antibodies) domain containing protein 1 (TIM1 (show TIMELESS Antibodies)) to be under positive natural selection in primates.
Urinary L-FABP (show FABP1 Antibodies), NGAL (show LCN2 Antibodies), Kim-1 and albumin (show ALB Antibodies) levels increased during the acute phase of kidney injury and were significantly correlated with the degree of tubulointerstitial fibrosis during the chronic phase. These markers could detect higher risk of progression to CKD.
Blockade of Tim-1 changes Th1 (show HAND1 Antibodies)/Th2 balance and reduces circulating regulatory T cells to enhance atherosclerosis in LDL receptor (show LDLR Antibodies) knockout mice.
Our results suggest that KIM-1 is an endogenous protective mechanism against renal ischemia-reperfusion injury
data suggest that TIM-1 signaling plays a direct role in Breg maintenance and induction both under physiological conditions (in response to ACs (show Acsl1 Antibodies)) and in response to therapy through TIM-1 ligation
Deletion of the mucin (show SLC13A2 Antibodies) domain impaired KIM-1-mediated phagocytic function, resulting in increased proinflammatory cytokine production, decreased antiinflammatory growth factor secretion by proximal epithelial cells, and an increase in tissue macrophages.
Tim-1 is critical for maintaining self-tolerance by regulating IL-10 (show IL10 Antibodies) production in Bregs
Tim-1 expression was lower in a herpes simplex virus-induced Behcet's disease (BD) mouse model compared to that in asymptomatic BD normal (BDN) mice.
Tim-1-Fc protects cardiac grafts from chronic rejection by suppressing CD4 (show CD4 Antibodies) Th17 development and functionality.
KIM-1 shedding is accelerated by worsening renal cellular injury, and excess soluble KIM-1 competitively inhibits efferocytosis.
Endogenous Tim-1 promotes severe systemic autoimmunity and renal disease MRL-Fas(lpr (show FAS Antibodies)) mice.
Study emphasizes a strong association of the tubular biomarker KIM-1 with chronic kidney disease progression in chronic heart failure and suggests usefulness as cardiorenal marker.
Accumulation of adipose tissue in the RS is related with the visceral adipose amount, KIM-1 and FGF-21 (show FGF21 Antibodies) concentration increase in the blood serum.
KIM-1 expression also enhances ERK MAPK (show MAPK1 Antibodies) activation, and the modulatory effect of KIM-1 on cellular repair process is likely mediated via ERK MAPK (show MAPK1 Antibodies) signaling pathway.
KIM-1 may mediate high glucose-induced autophagy and apoptosis in renal tubular epithelial cells.
Study suggests that TIM1 -416G>C and -1454G>A single nucleotide polymorphisms are associated with dilated cardiomyopathy susceptibility and prognosis in this Han Chinese population.
elevated baseline plasma KIM-1 strongly associated with risk of early progressive renal decline in type 1 diabetes
Urinary KIM-1 levels increased significantly in patients with contrast-induced nephropathy.
Data show that kidney injury molecule (KIM)-1 and neutrophil gelatinase-associated lipocalin (NGAL (show LCN2 Antibodies)), were significantly elevated in welding workers post-exposure.
High NGAL (show LCN2 Antibodies) and KIM-1 levels may indicate early diabetic kidney injury; however, we did not observe any relationship between these markers and diabetic indices
Kidney injury molecule-1 and neutrophil gelatinase-associated lipocalin (show LCN2 Antibodies) excretion rates correlated with excretion rates of other tubular damage markers and predicted outcome in patients with idiopathic membranous nephropathy
The protein encoded by this gene is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. The encoded protein may be involved in the moderation of asthma and allergic diseases. The reference genome represents an allele that retains a MTTVP amino acid segment that confers protection against atopy in HHAV seropositive individuals. Three transcript variants encoding the same protein have been found for this gene.
hepatitis A virus cellular receptor 1
, T-cell immunoglobulin and mucin domain containing 1
, hepatitis A virus cellular receptor 1 homolog
, kidney injury molecule 1
, t cell immunoglobulin and mucin domain-containing protein 1
, t cell membrane protein 1
, T cell immunoglobin domain and mucin domain protein 1
, T-cell membrane protein 1
, rho guanine nucleotide exchange factor 5