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The protein encoded by HAVCR1 is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. Additionally we are shipping HAVCR1 Kits (87) and HAVCR1 Proteins (34) and many more products for this protein.
Showing 10 out of 182 products:
Human Polyclonal HAVCR1 Primary Antibody for WB - ABIN318766
Meyers, Sabatos, Chakravarti, Kuchroo: The TIM gene family regulates autoimmune and allergic diseases. in Trends in molecular medicine 2005
Show all 2 references for ABIN318766
Human Polyclonal HAVCR1 Primary Antibody for EIA, IHC (p) - ABIN500911
Feigelstock, Thompson, Mattoo, Zhang, Kaplan: The human homolog of HAVcr-1 codes for a hepatitis A virus cellular receptor. in Journal of virology 1998
Human Polyclonal HAVCR1 Primary Antibody for WB - ABIN657951
Fontaine-Bisson, Renström, Rolandsson, , Payne, Hallmans, Barroso, Franks: Evaluating the discriminative power of multi-trait genetic risk scores for type 2 diabetes in a northern Swedish population. in Diabetologia 2010
Human Polyclonal HAVCR1 Primary Antibody for WB - ABIN2782775
de Souza, Oak, Jordanhazy, DeKruyff, Fruman, Kane: T cell Ig and mucin domain-1-mediated T cell activation requires recruitment and activation of phosphoinositide 3-kinase. in Journal of immunology (Baltimore, Md. : 1950) 2008
Data suggest that T-cell immunoglobulin domain and mucin (show SLC13A2 Antibodies) domain containing protein 1 (TIM1 (show TIMELESS Antibodies)) to be under positive natural selection in primates.
Blockade of Tim-1 changes Th1 (show HAND1 Antibodies)/Th2 balance and reduces circulating regulatory T cells to enhance atherosclerosis in LDL receptor (show LDLR Antibodies) knockout mice.
Our results suggest that KIM-1 is an endogenous protective mechanism against renal ischemia-reperfusion injury
data suggest that TIM-1 signaling plays a direct role in Breg maintenance and induction both under physiological conditions (in response to ACs (show Acsl1 Antibodies)) and in response to therapy through TIM-1 ligation
Deletion of the mucin (show SLC13A2 Antibodies) domain impaired KIM-1-mediated phagocytic function, resulting in increased proinflammatory cytokine production, decreased antiinflammatory growth factor secretion by proximal epithelial cells, and an increase in tissue macrophages.
Tim-1 is critical for maintaining self-tolerance by regulating IL-10 (show IL10 Antibodies) production in Bregs
Tim-1 expression was lower in a herpes simplex virus-induced Behcet's disease (BD) mouse model compared to that in asymptomatic BD normal (BDN) mice.
Tim-1-Fc protects cardiac grafts from chronic rejection by suppressing CD4 (show CD4 Antibodies) Th17 development and functionality.
KIM-1 shedding is accelerated by worsening renal cellular injury, and excess soluble KIM-1 competitively inhibits efferocytosis.
Endogenous Tim-1 promotes severe systemic autoimmunity and renal disease MRL-Fas(lpr (show FAS Antibodies)) mice.
a major P-selectin (show SELP Antibodies) ligand with a role in T cell trafficking during inflammatory responses and the induction of autoimmune disease
High NGAL (show LCN2 Antibodies) and KIM-1 levels may indicate early diabetic kidney injury; however, we did not observe any relationship between these markers and diabetic indices
Kidney injury molecule-1 and neutrophil gelatinase-associated lipocalin (show LCN2 Antibodies) excretion rates correlated with excretion rates of other tubular damage markers and predicted outcome in patients with idiopathic membranous nephropathy
The aim of this review article is to summarize the literature data concerning KIM-1 as a potential novel marker in the early diagnosis and prediction of clinical outcome of certain cardiovascular diseases.
Activation of TIM1 (show ARHGEF5 Antibodies) by exposing the cells to TIM4 (show TIMD4 Antibodies) significantly increased the frequency of apoptotic colon cancer cells. The expression of FasL (show FASL Antibodies) was increased in the cancer cells after treating by TIM4 (show TIMD4 Antibodies).
Urine KIM1 level was higher in kidney stone patients before lithotripsy than in healthy controls.
Urinary levels of NGAL (show LCN2 Antibodies) are more sensitive than uKIM-1 and uL-FABP (show FABP2 Antibodies) levels in predicting renal scarring in vesicoureteral reflux.
TIM-1 (show ARHGEF5 Antibodies) ligands increase the amount of cell surface protein (show CD28 Antibodies), preventing its traffic to the immune synapse
Urinary KIM-1 measured 24 h after the start of drug infusion has the potential to detect early AKI in pediatric patients treated with MTX (show MTX1 Antibodies) or platinum-class drugs
Urinary KIM-1 is a significant predictor of death in extremely low-birth-weight neonates.
Urinary KIM1 is significantly higher in patients with clear cell renal carcinoma (show TSC2 Antibodies) than in controls. Urinary KIM1 decreases after nephrectomy in clear cell renal carcinoma (show TSC2 Antibodies) patients.
The protein encoded by this gene is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. The encoded protein may be involved in the moderation of asthma and allergic diseases. The reference genome represents an allele that retains a MTTVP amino acid segment that confers protection against atopy in HHAV seropositive individuals. Three transcript variants encoding the same protein have been found for this gene.
hepatitis A virus cellular receptor 1
, T-cell immunoglobulin and mucin domain containing 1
, hepatitis A virus cellular receptor 1 homolog
, kidney injury molecule 1
, t cell immunoglobulin and mucin domain-containing protein 1
, t cell membrane protein 1
, T cell immunoglobin domain and mucin domain protein 1
, T-cell membrane protein 1
, rho guanine nucleotide exchange factor 5