Heterogeneous Nuclear Ribonucleoprotein A1 Proteins (HNRNPA1)

HNRNPA1 belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). Additionally we are shipping Heterogeneous Nuclear Ribonucleoprotein A1 Antibodies (125) and Heterogeneous Nuclear Ribonucleoprotein A1 Kits (17) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HNRNPA1 3178 P09651
HNRNPA1 15382 P49312
HNRNPA1 29578 P04256
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Top Heterogeneous Nuclear Ribonucleoprotein A1 Proteins at antibodies-online.com

Showing 10 out of 16 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 19 Days
$407.00
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
$333.33
Details
Yeast Macaca mulatta His tag   1 mg Log in to see 60 to 71 Days
$2,858.17
Details
Yeast Pan troglodytes His tag   1 mg Log in to see 60 to 71 Days
$2,858.17
Details
Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$2,858.17
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$2,858.17
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 2 to 3 Days
$534.64
Details

HNRNPA1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, , ,
Mouse (Murine)

Rat (Rattus)

Top referenced Heterogeneous Nuclear Ribonucleoprotein A1 Proteins

  1. Human HNRNPA1 Protein expressed in HEK-293 Cells - ABIN2722904 : Zheng, Worthington, Timms, Woo: HNRNPA1 interacts with a 5'-flanking distal element of interleukin-6 and upregulates its basal transcription. in Genes and immunity 2013 (PubMed)

More Proteins for Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) Interaction Partners

Human Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) interaction partners

  1. The hnRNP A1 binding map can be used to identify potential targets for splice-switching oligonucleotides-based therapy.

  2. Biophysical titrations reveal that the 5'-AUAGC-3' bulge undergoes a conformational change to assemble a functional hnRNP A1-human enterovirus 71 RNA complex.

  3. PRMT5 (show PRMT5 Proteins) regulates internal ribosome entry site-dependent translation via methylation of hnRNP A1.

  4. KRAS-E2F1-ILK-hnRNPA1 regulatory loop enables pancreatic cancer cells to promote oncogenic KRAS signaling and to interact with the tumor microenvironment to promote aggressive phenotypes.

  5. findings suggest that a new player, i.e., O-GlcNAcylation, regulates hnRNP A1 translocation and interaction with Trn1, possibly affecting its function

  6. The results of this study suggest that hnRNPA1 is the causative gene in the family with flail (show MYO5A Proteins) arm ALS (show IGFALS Proteins). This further expanded the disease phenotype of hnRNPA1 mutations.

  7. Introduction of point mutations into the hnRNP A1-binding site or knockdown of hnRNP A1 expression promoted human papillomavirus 18 233;416 splicing and reduced E6 expression.

  8. Studies provides evidence that hnRNP A1 is a new autoantigen of Behcet's Disease and associated with deep vein thrombosis.

  9. these data suggest that the level of hnRNPA1 is strictly controlled to be within a certain range by the mRNA autoregulation in the physiological condition so that the cytotoxicity-causative alteration of hnRNPA1 expression does not take place.

  10. The CCAT1/miR (show MLXIP Proteins)-490/hnRNPA1 axis promotes gastric cancer migration, and it may have a possible diagnostic and therapeutic potential in gastric cancer.

Mouse (Murine) Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) interaction partners

  1. PRMT5 (show PRMT5 Proteins) regulates internal ribosome entry site-dependent translation via methylation of hnRNP A1.

  2. Resveratrol causes a shift from the mesenchymal-specific forms of these factors to the respective epithelial forms and increases the expression of the RNA-binding proteins KHSRP (show KHSRP Proteins) and hnRNPA1.

  3. this study identified hnRNPA1, an RNA-binding protein and auxiliary splicing factor (show SLU7 Proteins), as a substrate of TRAF6 (show TRAF6 Proteins); TRAF6 (show TRAF6 Proteins) ubiquitination of hnRNPA1 regulated alternative splicing of Arhgap1 (show ARHGAP1 Proteins), which resulted in activation of the GTP-binding (show RND2 Proteins) Rho family protein Cdc42 (show CDC42 Proteins) and accounted for hematopoietic defects in TRAF6 (show TRAF6 Proteins)-expressing hematopoietic stem/ progenitor cells

  4. hnRNP A1 improves intestinal injury in anti-CD3 (show CD3E Proteins) antibody-induced enteritis mice through the upregulation of TFF2 (show TFF2 Proteins), which regulates apoptosis and enhances epithelial restoration

  5. Relevant to biological processes anticipated for hnRNP A1 and HuR (show ELAVL1 Proteins).

  6. This study provides evidence that PCBP2 (show PCBP2 Proteins) and hnRNP A1 bind to the 5' and 3' ends of the murine norovirus 1 viral RNA and contribute to RNA circularization, playing a role in the virus life cycle.

  7. Heteronuclear ribonucleoprotein A1 interacts with an element that overlaps the 5' splice site of Mag (show MAG Proteins) exon 12.

  8. MMP-3 (show MMP3 Proteins)-triggered Rac1 splicing regulation is modulated by hnRNP A1

  9. the phosphorylation status of hnRNP A1 serine 199 regulates the AKT (show AKT1 Proteins)-dependent sensitivity of cells to rapamycin and functionally links IRES-transacting factor annealing activity to cellular responses to mTOR (show FRAP1 Proteins) complex 1 inhibition.

  10. eIF2alpha (show EIF2A Proteins) phosphorylation during hypertonic stress promotes apoptosis by sequestration of specific mRNAs in SGs (show SKI Proteins) in a process mediated by the cytoplasmic accumulation of hnRNP A1

Pig (Porcine) Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) interaction partners

  1. the swine HNRPA1 gene was moderately expressed in fat, spleen and kidney, weakly expressed in muscle and lung, and hardly expressed in small intestine, large intestine and liver.

Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) Protein Profile

Protein Summary

This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It is one of the most abundant core proteins of hnRNP complexes and it is localized to the nucleoplasm. This protein, along with other hnRNP proteins, is exported from the nucleus, probably bound to mRNA, and is immediately re-imported. Its M9 domain acts as both a nuclear localization and nuclear export signal. The encoded protein is involved in the packaging of pre-mRNA into hnRNP particles, transport of poly A+ mRNA from the nucleus to the cytoplasm, and may modulate splice site selection. It is also thought have a primary role in the formation of specific myometrial protein species in parturition. Multiple alternatively spliced transcript variants have been found for this gene but only two transcripts are fully described. These variants have multiple alternative transcription initiation sites and multiple polyA sites.

Gene names and symbols associated with HNRNPA1

  • heterogeneous nuclear ribonucleoprotein A1 (hnrnpa1)
  • heterogeneous nuclear ribonucleoprotein A1-like 2 (HNRNPA1L2)
  • heterogeneous nuclear ribonucleoprotein A1 (LOC100101226)
  • Heterogeneous nuclear ribonucleoprotein A1 (roa1)
  • heterogeneous nuclear ribonucleoprotein A1 (HNRNPA1)
  • heterogeneous nuclear ribonucleoprotein A1 (Hnrnpa1)
  • heterogeneous nuclear ribonucleoprotein A1 (LOC100359118)
  • ribonucleoprotein A1a (hnrnpa1)
  • D15Ertd119e protein
  • Hdp protein
  • hnrnp-A1 protein
  • HNRNPA1 protein
  • hnRNP A1 protein
  • Hnrpa1 protein
  • HNRPA1L3 protein
  • ROA1 protein
  • TPT1P protein

Protein level used designations for HNRNPA1

heterogeneous nuclear ribonucleoprotein A1 , hnRNP core protein A1 , helix-destabilizing protein , single-strand-binding protein , hormonally upregulated Neu-associated kinase , Heterogeneous nuclear ribonucleoprotein A1 , heterogeneous ribonuclear particle protein , hnRNP A1 , Putative heterogeneous nuclear ribonucleoprotein A1-like 3 , heterogeneous nuclear ribonucleoprotein A1B protein , heterogeneous nuclear ribonucleoprotein B2 protein , heterogeneous nuclear ribonucleoprotein core protein A1 , hnRNP A1-like 3 , hnRNP core protein A1-like 3 , nuclear ribonucleoprotein particle A1 protein , single-strand DNA-binding protein UP1 , single-strand RNA-binding protein , HDP-1 , helix destabilizing protein , topoisomerase-inhibitor suppressed , UP1 , unwinding protein 1 , HDP , hnRNP A1-gamma isoform , heterogeneous nuclear ribonucleoproteins A1 homolog

GENE ID SPECIES
378453 Danio rerio
739306 Pan troglodytes
100101226 Bombyx mori
100195734 Salmo salar
380381 Xenopus laevis
496507 Xenopus (Silurana) tropicalis
3178 Homo sapiens
15382 Mus musculus
768103 Sus scrofa
505093 Bos taurus
29578 Rattus norvegicus
100359118 Oryctolagus cuniculus
100726972 Cavia porcellus
747284 Pan troglodytes
702977 Macaca mulatta
397751 Xenopus laevis
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