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Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. Additionally we are shipping HNRNPL Kits (12) and HNRNPL Proteins (6) and many more products for this protein.
Showing 10 out of 90 products:
Mouse (Murine) Monoclonal HNRNPL Primary Antibody for ICC, FACS - ABIN108589
Piñol-Roma, Swanson, Gall, Dreyfuss: A novel heterogeneous nuclear RNP protein with a unique distribution on nascent transcripts. in The Journal of cell biology 1990
Show all 10 references for ABIN108589
Amphibian Monoclonal HNRNPL Primary Antibody for ELISA, ICC - ABIN267487
Söderberg, Raffalli-Mathieu, Lang et al.: Inflammation modulates the interaction of heterogeneous nuclear ribonucleoprotein (hnRNP) I/polypyrimidine tract binding protein and hnRNP L with the 3'untranslated region of the murine inducible ... in Molecular pharmacology 2002
Show all 8 references for ABIN267487
Human Polyclonal HNRNPL Primary Antibody for EIA, WB - ABIN453681
Hahm, Cho, Kim, Kim, Kim, Oh, Jang: Polypyrimidine tract-binding protein interacts with HnRNP L. in FEBS letters 1998
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Human Polyclonal HNRNPL Primary Antibody for IHC (p), WB - ABIN650773
Funke, Zuleger, Benavente, Schuster, Goller, Stévenin, Horak: The mouse poly(C)-binding protein exists in multiple isoforms and interacts with several RNA-binding proteins. in Nucleic acids research 1996
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Human Polyclonal HNRNPL Primary Antibody for IF, IHC - ABIN1533621
Rasmussen, van Damme, Puype, Gesser, Celis, Vandekerckhove: Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes. in Electrophoresis 1993
Cow (Bovine) Polyclonal HNRNPL Primary Antibody for IF, IP - ABIN2778777
Guang, Felthauser, Mertz: Binding of hnRNP L to the pre-mRNA processing enhancer of the herpes simplex virus thymidine kinase gene enhances both polyadenylation and nucleocytoplasmic export of intronless mRNAs. in Molecular and cellular biology 2005
hnRNPA2B1 (show HNRNPA2B1 Antibodies), hnRNPD (show HNRNPD Antibodies), hnRNPL , and YBX1 (show YBX1 Antibodies) might play important roles in gastric cancer tumorigenesis.
hnRNP L controls inclusion of a broad spectrum of alternative cassette exons in T cells.
The study presents the structural characterization of the RNA recognition motif domains of hnRNP-L and demonstrate their function in repressing exon 4 of SLC2A2 (show SLC2A2 Antibodies).
HnRNP C (show HNRNPC Antibodies), YB-1 (show YBX1 Antibodies) and hnRNP L coordinately enhance skipping of human MUSK (show MUSK Antibodies) exon 10 to generate a Wnt (show WNT2 Antibodies)-insensitive MuSK (show MUSK Antibodies) isoform.
Data suggest that incorporation of 3(S)-methyl-beta-alanine into a short alpha-helical region of nucleic acid binding domain of hnRNP (show HNRNPC Antibodies) LL significantly stabilizes helix without affecting its DNA binding properties.
Our results reveal that hnRNP L is a new regulator for CD44 (show CD44 Antibodies) V10 exon splicing.
hnRNP K (show HNRNPK Antibodies) and hnRNP L may serve as A1CF (show A1CF Antibodies)-like cofactors in AID-mediated class switch recombination and somatic hypermutation
Results show that HNRNPL represses splicing when bound to intronic regions upstream of alternative exons, and in contrast, activates splicing when bound to the downstream intron.
hnRNP L is a potential biomarker for the diagnosis of HBV-HCC (show FAM126A Antibodies) and show that hnRNP L contributes to HCC (show FAM126A Antibodies) progression.
HnRNP L and hnRNP (show HNRNPC Antibodies) LL antagonistically modulate PTB (show PTBP1 Antibodies)-mediated splicing suppression of CHRNA1 (show CHRNA1 Antibodies) pre-mRNA.
Hnrnpl binds to p53 (show TP53 Antibodies) and inhibits its activation in mouse embryonic stem cells.
Aire (show AIRE Antibodies)-containing complexes include 7SK RNA, the latter interaction disrupted by HNRNPL knockdown, suggesting that HNRNPL may partake in delivering inactive P-TEFb (show CCNT1 Antibodies) to Aire (show AIRE Antibodies)
Results identify a cancer-specific mechanism of hnRNP L phosphorylation and subsequent lowering of the caspase (show CASP3 Antibodies)-9a/9b ratio, which is required for the tumorigenic capacity of non-small cell lung cancer cells.
identified hnRNP L as a novel Sam68 (show KHDRBS1 Antibodies)-interacting protein partner.
Inflammation modulates the interaction of hnRNP I (show PTBP1 Antibodies) and hnRNP L with the 3'untranslated region of the murine inducible nitric-oxide synthase (show NOS2 Antibodies) mRNA
decreased surface alpha2beta1 results from decreased Itga2 (show ITGA2 Antibodies) pre-mRNA splicing regulated by hnRNP L and depends on CA repeat length at a specific site in intron 1
iNOS (show NOS2 Antibodies) mRNA degradation is promoted upon binding of hnRNPI (show PTBP1 Antibodies) and hnRNPL to a destabilizing region within its 3'-UTR (show UTS2R Antibodies)
Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions. Two transcript variants encoding different isoforms have been found for this gene.
RNA-binding protein XlhnRNPL
, heterogeneous nuclear ribonucleoprotein L
, Heterogeneous nuclear ribonucleoprotein L
, hnRNP L
, heterogenous nuclear ribonucleoprotein L