HNRNPL antibody (Heterogeneous Nuclear Ribonucleoprotein L)

Details for Product anti-HNRNPL Antibody No. ABIN108588, Supplier: Log in to see
Antigen
  • hnrnpl
  • hnrpl
  • wu:fb53f10
  • wu:fp61c04
  • zgc:66175
  • HNRNPL
  • HNRPL
  • hnRNP-L
  • C79783
  • D830027H13Rik
  • Hnrpl
  • zgc:55429
  • hnrnp-L
  • RNA-binding protein XlhnRNPL
  • heterogeneous nuclear ribonucleoprotein L2
  • heterogeneous nuclear ribonucleoprotein L
  • Heterogeneous nuclear ribonucleoprotein L
  • hnrpl
  • hnrnpl2
  • HNRNPL
  • Hnrnpl
  • hnrnpl
Reactivity
Mouse (Murine), Rat (Rattus), Human, Newt
92
45
30
22
14
14
14
10
7
7
5
5
4
3
3
2
1
Host
Mouse
56
36
Clonality (Clone)
Monoclonal ()
Conjugate
This HNRNPL antibody is un-conjugated
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), ELISA, Western Blotting (WB)
87
39
38
32
26
18
16
12
5
2
1
1
1
Options
Supplier
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Immunogen Human hnRNP proteins (from HeLa cells) purified by affinity chromatography on ssDNA agarose
Clone 4D11
Isotype IgG1
Purification Protein A
Alternative Name hnRNP L (HNRNPL Antibody Abstract)
Background Synonyms:
D830027H13Rik antibody,FLJ35509 antibody,Heterogeneous nuclear ribonucleoprotein L antibody,hnRNPLantibody,hnRPL antibody,P/OKcl.14 antibody
Gene ID 3191, 15388, 80846
OMIM 603083
UniProt Q8R081
Application Notes Optimal antibody dilution should be determined by titration, however as a guideline try, IHC-P: Use a concentration of 1 μg/mL. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. WB: 1/2000. Detects a band of approximately 64 kDa (predicted molecular weight: 64 kDa). Flow Cyt: Use 1 μg for 106 cells.
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer Purified antibody (from supernatant) containing PBS 0.1 % sodium azide,
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Supplier Images
Western Blotting (WB) image for anti-HNRNPL antibody (Heterogeneous Nuclear Ribonucleoprotein L) (ABIN108588) Western blot for anti-hnRNP-L on HeLa cell extracts
 image for anti-HNRNPL antibody (Heterogeneous Nuclear Ribonucleoprotein L) (ABIN108588) anti-Heterogeneous Nuclear Ribonucleoprotein L (HNRNPL) antibody (Image 2)
 image for anti-HNRNPL antibody (Heterogeneous Nuclear Ribonucleoprotein L) (ABIN108588) anti-Heterogeneous Nuclear Ribonucleoprotein L (HNRNPL) antibody (Image 3)
Product cited in: Peddigari, Li, Rabe, Martin: "hnRNPL and nucleolin bind LINE-1 RNA and function as host factors to modulate retrotransposition." in: Nucleic acids research, Vol. 41, Issue 1, pp. 575-85, 2012 (PubMed).

Motta-Mena, Smith, Mallory, Jackson, Wang, Lynch: "A disease-associated polymorphism alters splicing of the human CD45 phosphatase gene by disrupting combinatorial repression by heterogeneous nuclear ribonucleoproteins (hnRNPs)." in: The Journal of biological chemistry, Vol. 286, Issue 22, pp. 20043-53, 2011 (PubMed).

Heyd, Lynch: "Phosphorylation-dependent regulation of PSF by GSK3 controls CD45 alternative splicing." in: Molecular cell, Vol. 40, Issue 1, pp. 126-37, 2010 (PubMed).

Wang, Cambi: "Heterogeneous nuclear ribonucleoproteins H and F regulate the proteolipid protein/DM20 ratio by recruiting U1 small nuclear ribonucleoprotein through a complex array of G runs." in: The Journal of biological chemistry, Vol. 284, Issue 17, pp. 11194-204, 2009 (PubMed).

Niu, Terasaki, Komatsu, Noguchi, Shichijo, Itoh: "Identification of peptides applicable as vaccines for HLA-A26-positive cancer patients." in: Cancer science, Vol. 100, Issue 11, pp. 2167-74, 2009 (PubMed).

Jia, Liu, Tao, Kruhlak, Guo, Meyers, Baker, Zheng: "Control of the papillomavirus early-to-late switch by differentially expressed SRp20." in: Journal of virology, Vol. 83, Issue 1, pp. 167-80, 2008 (PubMed).

Venables, Koh, Froehlich, Lapointe, Couture, Inkel, Bramard, Paquet, Watier, Durand, Lucier, Gervais-Bird, Tremblay, Prinos, Klinck, Elela, Chabot: "Multiple and specific mRNA processing targets for the major human hnRNP proteins." in: Molecular and cellular biology, Vol. 28, Issue 19, pp. 6033-43, 2008 (PubMed).

Rothrock, House, Lynch: "HnRNP L represses exon splicing via a regulated exonic splicing silencer." in: The EMBO journal, Vol. 24, Issue 15, pp. 2792-802, 2005 (PubMed).

Piñol-Roma, Swanson, Gall, Dreyfuss: "A novel heterogeneous nuclear RNP protein with a unique distribution on nascent transcripts." in: The Journal of cell biology, Vol. 109, Issue 6 Pt 1, pp. 2575-87, 1990 (PubMed).

Background publications Melton, Jackson, Wang, Lynch: "Combinatorial control of signal-induced exon repression by hnRNP L and PSF." in: Molecular and cellular biology, Vol. 27, Issue 19, pp. 6972-84, 2007 (PubMed).