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Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) (HNRNPU) ELISA Kits

HNRNPU belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). Additionally we are shipping Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) Antibodies (55) and Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
HNRNPU 51810 Q8VEK3
HNRNPU 117280  
HNRNPU 3192 Q00839
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Top Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) ELISA Kits at antibodies-online.com

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Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.057 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 9 to 11 Days
$736.84
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Pig
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$770.00
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Chicken
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$770.00
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Monkey
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$770.00
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Rabbit
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$770.00
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Guinea Pig
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$770.00
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Human
  96 Tests Log in to see 11 to 13 Days
$785.71
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Mouse
  96 Tests Log in to see 11 to 13 Days
$875.60
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Rat
  96 Tests Log in to see 16 to 21 Days
$999.43
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Dog
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$999.43
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More ELISA Kits for Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) Interaction Partners

Mouse (Murine) Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) (HNRNPU) interaction partners

  1. findings provide conclusive evidence for the essential role of hnRNP U in heart development and function and in the regulation of alternative splicing.

  2. SAF-A interacts with BRG1 and both components are required for RNA Polymerase II Mediated Transcription

  3. Macrophage expression of hnRNP U was induced by TLR stimulation. hnRNP U knockdown attenuated & overexpression increased TLR-induced expression of TNF-alpha (show TNF ELISA Kits), IL-6 (show IL6 ELISA Kits) & IL-1beta (show IL1B ELISA Kits). hnRNP U bound to the mRNA of these cytokines via the RGG motif.

  4. Data report that endogenous SAF-A is involved in regulation of Oct4 (show POU5F1 ELISA Kits) expression, binds the Oct4 (show POU5F1 ELISA Kits) proximal promoter in ES cells, and dissociates from the promoter upon early differentiation induced by LIF (show LIF ELISA Kits) withdrawal.

  5. hnRNP-U engages a highly neddylated active SCF (show KITLG ELISA Kits)beta-TrCP (show BTRC ELISA Kits)which dissociates in the presence of a high-affinity substrate, resulting in the ubiquitination of the latter.

  6. hnRNP U participates in nuclear regulatory events that are involved in mammalian central and peripheral circadian clocks.

  7. nuclear matrix protein SAF-A binds to the 3'-flanking region of the Bmal1 (show ARNTL ELISA Kits) gene with circadian timing

  8. HnRNP U binding to the 5'-UTR (show UTS2R ELISA Kits) of the Shh (show SHH ELISA Kits) facilitates gene expression during limb development.

  9. SAF-A was found to be localized in three different domains: outside the chromosomes, on the surface of the chromosome arms, and in the centromere region where it apparently binds specifically to the satellite DNA.

  10. the c-Myc (show MYC ELISA Kits)-Max complex exerts its transcriptional regulatory role and hnRNP U may be a coactivator of this transcriptional activator complex.

Human Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) (HNRNPU) interaction partners

  1. mutual regulatory mechanisms exist between PP4 (show ANXA5 ELISA Kits) and SAF-A. Interactions between PP4 (show ANXA5 ELISA Kits) and SAF-A played a role in prometaphase/metaphase transition.

  2. CENP-W (show CENPW ELISA Kits) interacts with hnRNPU and may contribute to kinetochore-microtubule attachment in mitotic cells.

  3. Nuclear TDP-43 (show TARDBP ELISA Kits) becomes neurotoxic by escaping from the inhibitory regulation by hnRNP-U or hnRNP (show HNRNPC ELISA Kits)-A2. hnRNP-U inhibits TDP-43 (show TARDBP ELISA Kits)-mediated alterations in splicing of POLDIP3 (show POLDIP3 ELISA Kits) mRNA.

  4. These results suggest that HNRNPU, FAM36A, and NCRNA00201 are not major genes for microcephaly and corpus callosum abnormalities but are good candidates for intellectual disability (ID) and seizures.

  5. both phosphorylation and dephosphorylation of SAF-A serine 59 by PLK1 and PP2A, respectively, are required for accurate and timely exit from mitosis.

  6. demonstrate that H19 inhibits RNA Pol II-mediated transcription by disrupting the hnRNP U-actin complex

  7. Induction of caspase (show CASP3 ELISA Kits)-9b expression is due to activation of hnRNP L (show HNRNPL ELISA Kits) via phosphorylation to compete/inhibit hnRNP U association with exon 3 of Casp9 (show CASP9 ELISA Kits) mRNA.

  8. the hnRNP-U protection of cells after oxidative stress is largely due to enhancement of NEIL1 (show NEIL1 ELISA Kits)-mediated repair.

  9. experimentally verified the targets heterogeneous nuclear ribonucleoprotein U, phosphatidylinositol-3-OH kinase, the WNK (with-no-lysine) kinase family and USP19 (ubiquitin-specific peptidase 19 (show USP19 ELISA Kits)) as vulnerable nodes in the host cellular defence system against viruses

  10. SAF-A interacts with BRG1 and both components are required for RNA Polymerase II Mediated Transcription

Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) (HNRNPU) Antigen Profile

Antigen Summary

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they form complexes with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene contains a RNA binding domain and scaffold-associated region (SAR)-specific bipartite DNA-binding domain. This protein is also thought to be involved in the packaging of hnRNA into large ribonucleoprotein complexes. During apoptosis, this protein is cleaved in a caspase-dependent way. Cleavage occurs at the SALD site, resulting in a loss of DNA-binding activity and a concomitant detachment of this protein from nuclear structural sites. But this cleavage does not affect the function of the encoded protein in RNA metabolism. At least two alternatively spliced transcript variants have been identified for this gene.

Gene names and symbols associated with HNRNPU

  • heterogeneous nuclear ribonucleoprotein U (Hnrnpu) antibody
  • heterogeneous nuclear ribonucleoprotein U (LOC100348766) antibody
  • heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) (HNRNPU) antibody
  • heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) (hnrnpu) antibody
  • heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) (Hnrnpu) antibody
  • AA408410 antibody
  • AI256620 antibody
  • AL024194 antibody
  • AL024437 antibody
  • AW557595 antibody
  • C86794 antibody
  • hnRNP U antibody
  • HNRPU antibody
  • saf-a antibody
  • SAFA antibody
  • SN1 antibody
  • Sp120 antibody
  • U21.1 antibody

Protein level used designations for HNRNPU

SAF-A , heterogenous nuclear ribonucleoprotein U , nuclear matrix protein sp120 , scaffold attachment factor A , system N1 Na+ and H+-coupled glutamine transporter , transporter protein , transporter protein; system N1 Na+ and H+-coupled glutamine transporter , heterogeneous nuclear ribonucleoprotein U , p120 nuclear protein , pp120

GENE ID SPECIES
51810 Mus musculus
117280 Rattus norvegicus
100348766 Oryctolagus cuniculus
3192 Homo sapiens
399374 Xenopus laevis
539950 Bos taurus
100515571 Sus scrofa
421492 Gallus gallus
100725944 Cavia porcellus
101107118 Ovis aries
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