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High Affinity Choline Transporter (ChT) ELISA Kits

Choline is a direct precursor of acetylcholine (ACh), a neurotransmitter of the central and peripheral nervous system that regulates a variety of autonomic, cognitive, and motor functions. Additionally we are shipping High Affinity Choline Transporter Antibodies (30) and and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse ChT ChT 63993 Q8BGY9
Anti-Human ChT ChT 60482 Q9GZV3
ChT 85426 Q9JMD7
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Top High Affinity Choline Transporter ELISA Kits at antibodies-online.com

Showing 1 out of 4 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Rat 28 pg/mL 78.13-5000 pg/mL 96 Tests Log in to see 9 to 11 Days
$800.00
Details

More ELISA Kits for High Affinity Choline Transporter Interaction Partners

Mouse (Murine) High Affinity Choline Transporter (ChT) interaction partners

  1. These data provide evidence for an epithelium-independent non-vesicular, non-quantal ACh (show FGFR3 ELISA Kits) release in the mouse trachea involving low-affinity choline transporters.

  2. bacterial artificial chromosome CHT mice thus represent a novel tool to examine both the positive and negative impact of constitutively elevated cholinergic signaling capacity

  3. These findings reveal compensatory mechanisms that, in the context of moderate cognitive challenges, can overcome the performance deficits expected from the significantly reduced ACh (show FGFR3 ELISA Kits) capacity of CHT+/- cholinergic terminals.

  4. CHT association with cholesterol-rich rafts is critical for its function

  5. This study showed that a constitutive loss of CHT expression in hemizygous mice leads to a significant reduction in basal extracellular dopamine levels in the nucleus accumbens.

  6. This study demonistrated that CHT support for neuromuscular signaling involves contributions to ACh (show FGFR3 ELISA Kits) synthesis as well as cholinergic synaptic vesicle availability.

  7. CHT1 knockout mice have tachycardia and hypertension at rest.

  8. CHT1 binds to Par-4 (show F2RL3 ELISA Kits) and inhibits choline uptake when its incorporation is reduced on the cell surface

  9. CHT is an essential and regulated presynaptic component of cholinergic signaling

  10. CHT1 was expressed early in CNS development, predominantly in the regions containing cholinergic neurons. NGF (show NGFB ELISA Kits) AND BMP4 (show BMP4 ELISA Kits) increased CHT mRNA accumulation in primary septal cultures.

Human High Affinity Choline Transporter (ChT) interaction partners

  1. These data show that acute exposure of depolarized cells to insulin (show INS ELISA Kits) is coupled to transiently increased levels of CHT proteins at the cell surface, and that this is attenuated by chronic insulin (show INS ELISA Kits) exposure.

  2. This study demonstrated a specific impairment in cognitive control associated with the Ile89Val polymorphism of SLC5A7.

  3. This mini-review discusses structural requirements for both organic cationic transporters OCT1 (show POU2F1 ELISA Kits) and OCT2 versus the blood-brain barrier choline transporter (BBBCHT) are discussed and compared.

  4. [review] The critical role of CHT in maintaining cholinergic transmission indicates that it could be a target for therapeutic intervention to promote acetylcholine synthesis, the accomplishment of which has not been adequately addressed.

  5. CHT1 forms a homo-oligomer on the cell surface in cultured cells.

  6. Our findings compel consideration of mutations in SLC5A7 or its functional partners in relation to unexplained motor neuronopathies.

  7. Polymorphic variation in the CHT1 gene can predict early, subclinical measures of carotid atherosclerosis.

  8. Nedd4-2 mediated ubiquitination regulates the cell surface expression of CHT1 in HEK293 cells.

  9. overexpressed ChAT enhanced transcription of the CHT1 gene but not the VACHT (show SLC18A3 ELISA Kits) gene

  10. The colocalisation of CHT1 immunoreactivity with VAChT (show SLC18A3 ELISA Kits) immunoreactivity in cholinergic enteric nerves in the human bowel thus suggests that CHT1 represents another marker of cholinergic nerves.

High Affinity Choline Transporter (ChT) Antigen Profile

Antigen Summary

Choline is a direct precursor of acetylcholine (ACh), a neurotransmitter of the central and peripheral nervous system that regulates a variety of autonomic, cognitive, and motor functions. SLC5A7 is a Na(+)- and Cl(-)- dependent high-affinity transporter that mediates the uptake of choline for acetylcholine synthesis in cholinergic neurons (Apparsundaram et al., 2000

Gene names and symbols associated with ChT

  • solute carrier family 5 (choline transporter), member 7 (SLC5A7) antibody
  • solute carrier family 5 (choline transporter), member 7 (Slc5a7) antibody
  • solute carrier family 5 (sodium/choline cotransporter), member 7 (SLC5A7) antibody
  • solute carrier family 5 (sodium/choline cotransporter), member 7 (Slc5a7) antibody
  • solute carrier family 6 (neurotransmitter transporter), member 8 (Slc6a8) antibody
  • V-set and immunoglobulin domain containing 1 (VSIG1) antibody
  • CHOT1 antibody
  • CHT antibody
  • Cht1 antibody
  • CRT antibody
  • CT1 antibody
  • hCHT antibody
  • HMN7A antibody

Protein level used designations for ChT

high affinity choline transporter 1 , CHT , hemicholinium-3-sensitive choline transporter , solute carrier family 5 member 7 , high affinity choline transporter; hemicholinium-3-sensitive choline transporter , solute carrier family 5 (choline transporter), member 7 , solute carrier family 5, member 7 , choline transporter , creatine transporter 1 , sodium- and chloride-dependent creatine transporter 1 , solute carrier family 6 (neurotransmitter transporter, creatine), member 8 , solute carrier family 6 member 8 , ChT1 thymocyte antigen , V-set and immunoglobulin domain-containing protein 1

GENE ID SPECIES
414870 Gallus gallus
512311 Bos taurus
63993 Mus musculus
60482 Homo sapiens
85426 Rattus norvegicus
50690 Rattus norvegicus
414795 Gallus gallus
481311 Canis lupus familiaris
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