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In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. Additionally we are shipping HNMT Proteins (18) and HNMT Kits (8) and many more products for this protein.
Showing 10 out of 74 products:
Human Polyclonal HNMT Primary Antibody for EIA, IHC (p) - ABIN356933
Aksoy, Raftogianis, Weinshilboum: Human histamine N-methyltransferase gene: structural characterization and chromosomal location. in Biochemical and biophysical research communications 1996
The present meta-analysis confirms published evidence suggesting that the HNMT rs11558538 minor allele is related to a reduced risk of developing Parkinson disease
The T allele of rs3787429 exhibited protective effect against CHF under the dominant and additive models , while, for SNPs in HRH2 (show DHX15 Antibodies), DAO (show ABP1 Antibodies), and HNMT, no significant associations were observed in the present study
HNMT is identified as a novel gene responsible for intellectual disability. The consequences of the identified missense mutations on the protein function are discussed.
HRH1 (show DHX8 Antibodies)-17 TT and HNMT-1639 TT genotypes were associated with the allergic asthma phenotype among African-American children and that the ABP (show ABP1 Antibodies) 4107 GG genotype was associated with nonallergic asthma among white children.
results suggest that the heterozygous Thr/Ile genotype at the HNMT-Thr105Ile locus and the minor Ile105 allele protect against Parkinson's disease and schizophrenia in Han Chinese.
The polymorphisms of HNMT and HRH3 (show HRH3 Antibodies) were irrelevant with breast cancer in the present study.
The A939G HNMT polymorphism is associated with autoimmune MG, while no association with C314T SNP was found.
The results of this study indicated that Histamine N-methyltransferase Thr105Ile polymorphism is associated Parkinson's disease.
Lack of the association of HNMT Thr105Ile functional polymorphism with Alzheimer's disease is found.
our results suggest that, despite the possible role of histamine in the inflammatory processes related with the pathogenesis of MS, HNMT polymorphism is not related with the risk for MS in Caucasian Spanish people
Genomic structure of the rat and mouse histamine N-methyltransferase gene
decreasing expression over the time course of the skin pathological changes in MRL/lpr (show FAS Antibodies) mice
In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.
, Histamine N-methyltransferase