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anti-Histidine Decarboxylase (HDC) Antibodies

HDC encodes a member of the group II decarboxylase family and forms a homodimer that converts L-histidine to histamine in a pyridoxal phosphate dependent manner. Additionally we are shipping Histidine Decarboxylase Proteins (17) and Histidine Decarboxylase Kits (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HDC 380629  
HDC 3067 P19113
HDC 24443  
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Top anti-Histidine Decarboxylase Antibodies at

Showing 10 out of 55 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB HDC Antibody (N-term) (ABIN658095) western blot analysis in NCI-H292 cell line lysates (35 µg/lane). This demonstrates the HDC antibody detected the HDC protein (arrow). 400 μL Log in to see 10 to 11 Days
Dog Rabbit Un-conjugated IHC (fro), IF, IHC (p), WB   50 μL Log in to see 6 to 8 Days
Human Rabbit Un-conjugated WB Western blot analysis of HDC expression in rat fetal liver tissue lysate. 100 μg Log in to see 2 to 3 Days
Human Rabbit Un-conjugated ELISA, IHC (p), WB Immunohistochemistry (IHC) analysis of paraffin-embedded Human Brain, antibody was diluted at 1:100. 100 μL Log in to see 14 Days
Mouse Rabbit Un-conjugated IHC (p), WB Anti-Histidine decarboxylase antibody, Western blotting Lane 1: Rat Brain Tissue Lysate Lane 2: Mouse Brain Tissue Lysate Anti-Histidine decarboxylase antibody, IHC(P) IHC(P): Rat Brain Tissue 100 μg Log in to see 4 to 6 Days
Human Rabbit Un-conjugated IHC, WB Immunohistochemistry of paraffin-embedded rat lung using HDC antibody at dilution of 1:200 (400x lens). 100 μL Log in to see 14 Days
Human Rabbit Un-conjugated IHC, ELISA, WB 0.1 mg Log in to see 2 to 6 Days
Rat Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
Human Rabbit Un-conjugated WB Western Blot: HDC Antibody [NBP2-16797] - Sample (30 ug of whole cell lysate) A: H1299 B: Molt-4 7. 5% SDS PAGE gel, diluted at 1:1000. 0.1 mL Log in to see 6 to 9 Days
Human Rabbit Un-conjugated IF (p), IHC (p), WB L1 mouse stomach lysates L2 mouse liver lysates probed with Anti HDC Polyclonal Antibody, Unconjugated (ABIN736986) at 1:200 in 4 °C. Followed by conjugation to secondary antibody at 1:3000 90min in 37 °C. Predicted band 73kD. Observed band size: 73kD 100 μL Log in to see 3 to 7 Days

HDC Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,

Human , ,

, , , , ,
Rat (Rattus) ,


Top referenced anti-Histidine Decarboxylase Antibodies

  1. Dog (Canine) Polyclonal HDC Primary Antibody for IHC (fro), IF - ABIN115730 : Dartsch, Persson: Recombinant expression of rat histidine decarboxylase: generation of antibodies useful for western blot analysis. in The international journal of biochemistry & cell biology 1998 (PubMed)
    Show all 4 references for ABIN115730

  2. Human Polyclonal HDC Primary Antibody for WB - ABIN658095 : Ercan-Sencicek, Stillman, Ghosh, Bilguvar, ORoak, Mason, Abbott, Gupta, King, Pauls, Tischfield, Heiman, Singer, Gilbert, Hoekstra, Morgan, Loring, Yasuno, Fernandez, Sanders, Louvi, Cho, Mane et al.: L-histidine decarboxylase and Tourette's syndrome. ... in The New England journal of medicine 2010 (PubMed)

More Antibodies against Histidine Decarboxylase Interaction Partners

Fruit Fly (Drosophila melanogaster) Histidine Decarboxylase (HDC) interaction partners

  1. genes encoding for proteins involved in histamine signaling [histidine decarboxylase (hdc), histamine-gated chloride channel (show CLCA1 Antibodies) subunit 1 (hisCl1), ora (show RHO Antibodies) transientless (ort)] cause abnormal temperature preferences

Zebrafish Histidine Decarboxylase (HDC) interaction partners

  1. Ethanol upregulates histidine decarboxylase expression in neural brain networks.

Mouse (Murine) Histidine Decarboxylase (HDC) interaction partners

  1. Lack of endogenous histamine in NOD HDC(-/-) mice decreased the incidence of diabetes in relation to their wild-type counterpart.

  2. the structure and function of the retina in mice that lacked expression of the rate limiting enzyme in the formation of histamine, histidine decarboxylase (Hdc-/- mouse), were investigated.

  3. SDS (show SDS Antibodies) induces itch through increased production of epidermal histamine, which results from an increase in the gene expression and post-translation processing of L-histidine decarboxylase.

  4. HDC, whose expression is remarkably downregulated during the first few days after birth in dermal cells of mice, plays essential roles in the hair-inducing ability of newborn mouse dermal cells

  5. An increased expression of H3 receptors in HDC KO mice without any changes in the spontaneous firing of "histaminergic" neurons without histamine and their responses to the H3 receptor agonist (R)-alpha-methylhistamine.

  6. Histidine decarboxylase was found at comparably high levels in mouse striatum.

  7. There was no difference in the levels of vascular endothelial growth factor between HDC-/- or wild-type mice, either in the lung or in bronchoalveolar-lavage cells.

  8. HDC-/- mice showed reduced severity of K/BxN serum-induced arthritis.

  9. in 12 day old embryonic stem cells histidine decarboxylase was confined to peripheral cells and small clusters of cells, inner cells were usually negative for it

  10. Metabolic phenotype of mice lacking histamine due to targeted disruption of histidine decarboxylase. Characterized by visceral adiposity, increased of brown adipose tissue, impaired glucose tolerance, hyperinsulinemia, and hyperleptinemia.

Human Histidine Decarboxylase (HDC) interaction partners

  1. Human enterochromaffin-like cells appear to partially co-express VMAT-2 (show Slc18a2 Antibodies) and HDC. Co-expression of VMAT-2 (show Slc18a2 Antibodies) and HDC might be required for increased histamine production in patients with gastric neuroendocrine tumors.

  2. The findings indicate that polymorphisms of HDC gene were significantly associated with breast cancer in Chinese Han population and may be novel diagnostic or therapeutic targets for breast cancer.

  3. HDC rs17740607 polymorphism is at least a partial loss-of-function variant and acts as a protective factor against chronic heart failure

  4. Investigated variation across the HDC (histidine decarboxylase) gene for association with Tourette Syndrome.

  5. HDC production in the stomach is associated with bile acid exposure and its related transcriptional regulation network of FXR (show NR1H4 Antibodies), SHP (show LAMC1 Antibodies), and CDX1 (show CDX1 Antibodies).

  6. Data indicate that histidine decarboxylase (HDC) is expressed by neutrophils.

  7. Structural study reveals that Ser (show SIGLEC1 Antibodies)-354 determines substrate specificity on human histidine decarboxylase.

  8. crystal of histidine decarboxylase belonged to space group C2, with unit-cell parameters a = 215.16, b = 112.72, c = 171.39 A, beta = 110.3 degrees

  9. It was shown that for serum and urine, HDC levels achieved sensitivities and specificities compatible to or even greater than those of established biomarkers for the diagnosis of intestinal mucosal injury in patients with acute intestinal obstruction.

  10. The novel concept that an autocrine loop, consisting of enhanced histamine synthesis by histidine decarboxylase, sustains cholangiocarcinoma growth is proposed.

Histidine Decarboxylase (HDC) Antigen Profile

Protein Summary

This gene encodes a member of the group II decarboxylase family and forms a homodimer that converts L-histidine to histamine in a pyridoxal phosphate dependent manner. Histamine regulates several physiologic processes, including neurotransmission, gastric acid secretion,inflamation, and smooth muscle tone.

Gene names and symbols associated with HDC

  • Histidine decarboxylase (Hdc) antibody
  • histidine decarboxylase (HDC) antibody
  • histidine decarboxylase (hdc) antibody
  • histidine decarboxylase (Desac_2880) antibody
  • histidine decarboxylase (LOC100313635) antibody
  • histidine decarboxylase (LOC100533309) antibody
  • headcase homolog (Drosophila) (Heca) antibody
  • histidine decarboxylase (Hdc) antibody
  • 4732480P20 antibody
  • anon-WO0140519.259 antibody
  • AW108189 antibody
  • CG3454 antibody
  • Dmel\\CG3454 antibody
  • Gm869 antibody
  • HDC antibody
  • Hdc-a antibody
  • Hdc-c antibody
  • Hdc-e antibody
  • Hdc-s antibody
  • HDCL antibody
  • JK910 antibody
  • LOC100313635 antibody

Protein level used designations for HDC

CG3454-PA , CG3454-PB , CG3454-PC , Hdc-PA , Hdc-PB , Hdc-PC , histidine decarboxylase , histidine-decarboxylase , histidine decarboxylase-like , headcase protein homolog , L-histidine decarboxylase

36076 Drosophila melanogaster
453425 Pan troglodytes
548615 Strongylocentrotus purpuratus
715287 Macaca mulatta
793609 Danio rerio
10438116 Desulfobacca acetoxidans DSM 11109
100313635 Saccoglossus kowalevskii
100407107 Callithrix jacchus
100435706 Pongo abelii
100533309 Aplysia californica
100583943 Nomascus leucogenys
380629 Mus musculus
3067 Homo sapiens
487551 Canis lupus familiaris
15186 Mus musculus
24443 Rattus norvegicus
100719978 Cavia porcellus
415454 Gallus gallus
100156724 Sus scrofa
515950 Bos taurus
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