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anti-Histidine Rich Calcium Binding Protein (HRC) Antibodies

HRC encodes a luminal sarcoplasmic reticulum protein identified by its ability to bind low-density lipoprotein with high affinity. Additionally we are shipping HRC Kits (3) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
Anti-Mouse HRC HRC 15464  
Anti-Rat HRC HRC 292905  
HRC 3270 P23327
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Top anti-HRC Antibodies at antibodies-online.com

Showing 10 out of 25 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue reacted with HRC / HCR Antibody (Center) followed which was peroxidase conjugated to the secondary antibody and followed by DAB staining. Western blot analysis of HRC / HCR Antibody (Center) in ZR-75-1 cell line lysates (35ug/lane). This demonstrates the HRC antibody detected the HRC protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB HRC Antibody (Center) (ABIN656657) immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Alkaline Phosphatase (AP) IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit APC IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Biotin IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit PE IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit FITC IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated IHC, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated WB   50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details

HRC Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,


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Top referenced anti-HRC Antibodies

  1. Human Polyclonal HRC Primary Antibody for EIA, IHC (p) - ABIN952794 : Arvanitis, Sanoudou, Kolokathis, Vafiadaki, Papalouka, Kontrogianni-Konstantopoulos, Theodorakis, Paraskevaidis, Adamopoulos, Dorn, Kremastinos, Kranias: The Ser96Ala variant in histidine-rich calcium-binding protein is associated with life-threatening ventricular arrhythmias in idiopathic dilated cardiomyopathy. in European heart journal 2008 (PubMed)

More Antibodies against HRC Interaction Partners

Mouse (Murine) Histidine Rich Calcium Binding Protein (HRC) interaction partners

  1. While CASQ2 (show CASQ2 Antibodies) stabilizes RyR2 (show RYR2 Antibodies) rendering it refractory in the diastolic phase, HRC enhances RyR2 (show RYR2 Antibodies) activity facilitating RyR2 (show RYR2 Antibodies) recovery from refractoriness.

  2. Ablation of HRC is associated with poorly regulated SR Ca(2 (show CA2 Antibodies)+)-cycling, and severe pathology under pressure-overload stress, suggesting an essential role of HRC in maintaining the integrity of cardiac function.

  3. Results identify the HRC enhancer as the first MEF2 (show MEF2C Antibodies)-dependent, CArG-motif-independent transcriptional target in smooth muscle and represent the first analysis of the transcriptional regulation of a sarcoplasmic reticulum gene in vivo.

  4. alterations in expression levels of HRC are associated with impaired cardiac SR Ca homeostasis and contractile function.

  5. HRC may be an integral regulatory protein involved in cardiac muscle SR Ca uptake and Ca homeostasis

  6. The exaggerated response of HRC knockout mice to the induction of cardiac hypertrophy is consistent with a regulatory role for HRC in calcium handling in vivo.

  7. Histidine-rich Ca-binding protein may play a key role in the regulation of SR Ca cycling through its direct interactions with SERCA2 (show ATP2A2 Antibodies) and triadin (show TRDN Antibodies), mediating a fine cross talk between SR Ca uptake and release in the heart.

Human Histidine Rich Calcium Binding Protein (HRC) interaction partners

  1. this study demonstrates a role of HRC in promoting hepatocellular carcinoma (HCC (show FAM126A Antibodies)) growth, besides its role in inducing HCC (show FAM126A Antibodies) metastasis, and highlights HRC as a promising intervention target for HCC (show FAM126A Antibodies).

  2. Up-regulation of histidine-rich calcium binding protein promotes tumor metastasis in hepatocellular carcinoma and is mediated by SATB1 (show SATB1 Antibodies).

  3. The S96A HRC mutation disrupts the Ca2 (show CA2 Antibodies)+ -microdomain around the RyR2 (show RYR2 Antibodies), as it alters the Ca2 (show CA2 Antibodies)+ -dependent association of RyR2 (show RYR2 Antibodies) and HRC.

  4. findings suggest that aberrant sarcoplasmic reticulum Ca2 (show CA2 Antibodies)+ release and increased susceptibility to delayed afterdepolarizations underlie triggered arrhythmic activity in Ala96 HRC carriers

  5. Results identify the HRC enhancer as the first MEF2 (show MEF2A Antibodies)-dependent, CArG-motif-independent transcriptional target in smooth muscle and represent the first analysis of the transcriptional regulation of a sarcoplasmic reticulum gene in vivo.

  6. alterations in expression levels of HRC are associated with impaired cardiac SR Ca homeostasis and contractile function.

  7. Histidine-rich Ca-binding protein may play a key role in the regulation of SR Ca cycling through its direct interactions with SERCA2 (show ATP2A2 Antibodies) and triadin (show TRDN Antibodies), mediating a fine cross talk between SR Ca uptake and release in the heart.

  8. The Ser96Ala genetic variant of HRC is associated with life-threatening ventricular arrhythmias in idiopathic DCM and may serve as an independent predictor of susceptibility to arrhythmogenesis in the setting of DCM.

HRC Antigen Profile

Protein Summary

This gene encodes a luminal sarcoplasmic reticulum protein identified by its ability to bind low-density lipoprotein with high affinity. The protein interacts with the cytoplasmic domain of triadin, the main transmembrane protein of the junctional sarcoplasmic reticulum (SR) of skeletal muscle. The protein functions in the regulation of releasable calcium into the SR.

Gene names and symbols associated with HRC

  • histidine rich calcium binding protein (HRC) antibody
  • histidine rich calcium binding protein (Hrc) antibody
  • DKFZp468J236 antibody

Protein level used designations for HRC

histidine rich calcium binding protein , histidine-rich calcium-binding protein , sarcoplasmic reticulum histidine-rich calcium-binding protein , histidine rich calcium-binding protein

GENE ID SPECIES
456413 Pan troglodytes
484386 Canis lupus familiaris
617610 Bos taurus
718647 Macaca mulatta
100049576 Equus caballus
100171720 Pongo abelii
100594612 Nomascus leucogenys
15464 Mus musculus
292905 Rattus norvegicus
3270 Homo sapiens
100009049 Oryctolagus cuniculus
Selected quality suppliers for anti-HRC (HRC) Antibodies
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