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The protein encoded by HAT1 is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Additionally we are shipping HAT1 Antibodies (94) and HAT1 Proteins (19) and many more products for this protein.
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we discover a novel function for the chromatin assembly-associated histone acetyltransferase complex NuB4 catalytic subunit HAT1 in oxidative stress response, antifungal drug tolerance as well as in fungal virulence
findings show that C. albicans requires a fully functional HAT1 complex for efficient repair of DNA damages, normal cell proliferation and maintenance of the yeast morphology.
Results show a novel interaction of the Lsm4 (show LSM4 ELISA Kits) RGG domain with HAT1 and RBBP7 (show RBBP7 ELISA Kits), leading to the possibility of a posttranslational modifications network involved in mRNP regulation.
These data indicated that miR-486 aggravate the cholesterol accumulation in THP-1 cells by targeting HAT1.
The expression of HAT1 was higher in the primary Esophageal carcinoma tumors and adjacent tissue as compared to that of the normal esophageal tissue and HAT1 expression was directly correlated with the poor tumor differentiation
Data indicate that HAT1 is required for homologous recombination in DNA repair.
HAT1 differentially impacts nucleosome assembly of H3.1-H4 and H3.3-H4.
the role of Hat1 in DNA damage repair is evolutionarily conserved, the ability of H3 acetylation to compensate for Hat1 deletion appears to be more variable
HAT (show MGEA5 ELISA Kits) gene expression is required for cisplatin resistance and Clock and Tip60 (show KAT5 ELISA Kits) regulate not only transcription, but also DNA repair, through periodic histone acetylation
Results suggests that Hat1-dependent acetylation of H4 is directly involved in the recruitment of several bromodomain-containing proteins to chromatin.
The acetyltransferase HAT1 moderates the NF-kappaB inflammatory response by regulating the transcription factor PLZF.
Hat1 is not only responsible for the acetylation of newly synthesized histone H4 but is also required to maintain the acetylation of histone H3 (show HIST3H3 ELISA Kits) on lysines 9, 18, and 27 during replication-coupled chromatin assembly.
Expression levels of Hat1 promoter mRNA are not significantly different in vitrified oocyte promoter compared with fresh oocytes.
The protein encoded by this gene is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5. Alternatively spliced transcript variants have been identified for this gene.
, histone acetyltransferase type B catalytic subunit
, histone aminotransferase 1
, HAT B
, histone acetyl transferase
, histidine aminotransferase 1
, histone acetyltransferase 1