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In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Additionally we are shipping Homeobox A11 Antibodies (67) and many more products for this protein.
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re-expression of hoxa11 and hoxa13 (show HOXA13 Proteins) in the froglet blastema is initiated although the subsequent proximal-distal patterning, including separation of the hoxa11 and hoxa13 (show HOXA13 Proteins) expression domains, is disrupted.
demonstrated that HOXA11-antisense(AS) functioned as a molecular sponge for miR (show MLXIP Proteins)-124, and overexpression of miR (show MLXIP Proteins)-124 attenuated the proliferation and invasion-promoting effect of HOXA11-AS
Bioinformatics prediction forecast that miR-140-5p directly targeted HOXA11-antisense RNA at 3'-UTR, which was confirmed by luciferase reporter assay
HOXA11-AS functions as a competing endogenous RNA.
our study demonstrated that HOXA11 function as a tumor suppressor in renal cell carcinoma (show MOK Proteins)
Regulated HOXA10 (show HOXA10 Proteins) and HOXA11 expression is necessary for endometrial receptivity; decreased HOXA10 (show HOXA10 Proteins) or HOXA11 expression leads to decreased implantation rates. Alternation of HOXA10 (show HOXA10 Proteins) and HOXA11 expression has been identified as a mechanism of the decreased implantation associated with endometriosis, polycystic ovarian syndrome, leiomyoma, polyps, adenomyosis, and hydrosalpinx.
Laparoscopic endometrioma resection increases peri (show PLIN1 Proteins)-implantation endometrial HOXA-11 mRNA expression.
Epigenetic silencing of HOXA11 promotes gastric cancer proliferation, migration and invasion through activation of Wnt (show WNT2 Proteins) signaling.
The overexpression of miR (show MLXIP Proteins)-30d or 181a suppressed HOXA11 mRNA.
Low HOXA11 expression is associated with hepatocellular carcinoma.
Mutations in the coding region of HOXA11 are not common in Chinese women with Mullerian duct anomalies.
The TM-induced characteristic changes in the expression pattern of Hoxa11 and Bmp4 (show BMP4 Proteins) on GDs (show PAEP Proteins) 10 and/or 11 were not noted
the derived functional cooperativity between HOXA11 and FOXO1 (show FOXO1 Proteins) is due to derived allosteric regulation of HOXA11 by FOXO1 (show FOXO1 Proteins).
On the basis of the polydactyly that we observed after expression of Hoxa11 in distal limbs, we propose that the evolution of Hoxa11 regulation contributed to the transition from polydactyl limbs in stem-group tetrapods to pentadactyl limbs in extant tetrapods.
Shox2 (show SHOX2 Proteins) expression restricted to the proximal limb along with Hoxd9 (show HOXD9 Proteins) and Hoxa11 expression, juxtaposing the distal expression of Hoxa13 (show HOXA13 Proteins) and Hoxd13 (show HOXD13 Proteins).
Hoxa-11 maintains cell proliferation in the mouse gubernaculum to facilitate testicular descent.
Hoxa11 and Hoxd11 (show HOXD11 Proteins) regulate chondrocyte differentiation upstream of Runx2 (show RUNX2 Proteins) and Shox2 (show SHOX2 Proteins) in mice.
Results reveal that Hoxa11 knockdown in the uterosacral ligaments and uterus increases extracellular matrix degradation.
Data show that the extra-embryonic function of Hoxa10 (show HOXA10 Proteins), -11, and -13 genes stems from their specific expression in the allantois, an extra-embryonic hallmark of amniote vertebrates.
Hox11 (show TLX1 Proteins) genes (Hoxa11, Hoxc11 (show HOXC11 Proteins) and Hoxd11 (show HOXD11 Proteins)) co-regulate and coordinate the development of zeugopod skeletal elements and adjacent elbow and knee joints, and dictate joint identity, morphogenesis and anatomical and functional organization.
mice individually mutant for Hoxa11 or Hoxd11 (show HOXD11 Proteins) show no discernible kidney abnormalities. Hoxa11/Hoxd11 (show HOXD11 Proteins) double mutants, however, demonstrate hypoplasia of the kidneys
Hoxa11 is required for proper cellular proliferation and apoptotic responses in the developing neonatal uterus.
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is involved in the regulation of uterine development and is required for female fertility. Mutations in this gene can cause radio-ulnar synostosis with amegakaryocytic thrombocytopenia.
, similar to Homeobox protein Hox-A11 (Hox-1.9)
, homeobox containing transcription factor
, homeobox protein Hox A11
, homeo box 1I
, homeobox protein HOXA11
, homeobox protein Hox-1I
, homeobox protein Hox-A11
, homeo box A11
, homeobox protein Hox-1.9
, homeo box A10
, homeobox protein A10
, homeodomain-containing protein