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Homeobox B5 Proteins (HOXB5)

HOXB5 is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. Additionally we are shipping HOXB5 Antibodies (68) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat HOXB5 HOXB5 497987  
HOXB5 3215 P09067
HOXB5 15413 P09079
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Top HOXB5 Proteins at antibodies-online.com

Showing 7 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Yeast Sheep His tag   1 mg Log in to see 56 to 66 Days
$2,007.50
Details
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$2,119.33
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$2,579.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 9 to 11 Days
$229.85
Details

HOXB5 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

Top referenced HOXB5 Proteins

  1. Human HOXB5 Protein expressed in Wheat germ - ABIN1306955 : Zhu, Kam, Garcia-Barceló, Tam, Lui: HOXB5 binds to multi-species conserved sequence (MCS+9.7) of RET gene and regulates RET expression. in The international journal of biochemistry & cell biology 2014 (PubMed)

More Proteins for Homeobox B5 (HOXB5) Interaction Partners

Zebrafish Homeobox B5 (HOXB5) interaction partners

  1. Conserved non-coding elements (CNEs) near the zebrafish hoxb5 genes, were characterized.

Human Homeobox B5 (HOXB5) interaction partners

  1. HOXB5 acts as a positive modulator by promoting cell proliferative response and invasiveness in ER-positive breast cancer.

  2. HOXB5 may be an important regulator of the Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signalling pathway, thereby contributing to gastric cancer progression and metastasis.

  3. Roles of Hoxb5 in the development of vagal and trunk neural crest cells.

  4. Overexpression of HoxB5 enhances blood vessel perfusion in vivo by up-regulation of MCP-1 (show CCL2 Proteins) and IL-6 (show IL6 Proteins) as well as in enhanced leucocyte infiltration and blood vessel remodelling.

  5. HOXB5 and HOXB8 (show HOXB8 Proteins) are frequently expressed in ovarian serous carcinoma, with anatomic site-related differences for cytoplasmic staining. HOXB5 may be affected by chemotherapy in effusions.

  6. The findings for HOXB5 and PHOX2B (show PHOX2B Proteins) provide supportive evidence that genes regulating ENCC proliferation, migration and differentiation could be risk factors for Hirschsprung's disease

  7. A miRNA 7-binding single nucleotide polymorphism (1010A/G) located within 3'-UTR of HOXB5 is associated with gene expression and may be a promising prognostic factor for bladder cancer.

  8. HOXB5, HOXB6 (show HOXB6 Proteins), and HOXB7 (show HOXB7 Proteins) are activated in Barrett esophagus, and the midcluster HOXB gene signature in BE most resembled the colon rather than other GI epithelia.

  9. Single nucleotide polymorphism in HOXB5 gene is associated with childhood obesity.

  10. results support that expression of HOX (show MSH2 Proteins) genes is associated with oral squamous cell carcinoma; over 90% of OSCC samples presented HOXB5 expression versus 60% of non-tumor tissues, it can be suggested that HOXB5 may be related to the malignant phenotypes.

Mouse (Murine) Homeobox B5 (HOXB5) interaction partners

  1. only the Hoxb5(+) hematopoietic stem cells exhibit long-term reconstitution capacity after transplantation in primary transplant recipients and, notably, in secondary recipients

  2. Data indicate that homeobox b5 (Hoxb5) regulated the neural crest (NC)development by directly inducing Forkhead box D3 (show FOXD3 Proteins) gene (Foxd3 (show FOXD3 Proteins)).

  3. The dysregulation of Hoxb5 signaling and early depletion of Neural crest cells contribute to enteric nervous system defect and other neurocristopathies in Hirschsprung disease patients deserves further investigation.

  4. TGF beta (show TGFB1 Proteins) inhibition enhanced airway branching, and Hoxb5 protein cellular localization was more diffuse.

  5. Hoxa5 (show HOXA5 Proteins) and Hoxb5 paralog genes share some functions during lung morphogenesis; Hoxa5 (show HOXA5 Proteins) plays a predominant role.

  6. HoxB5 is necessary and sufficient to activate the cell-intrinsic events that regulate the differentiation of angioblasts and mature endothelial cells from their mesoderm-derived precursors

  7. Ret (show RET Proteins) is a downstream target of Hoxb5 whose perturbation causes Ret (show RET Proteins) haploinsufficiency, impaired NCC (show SLC12A3 Proteins) migration, and hypo/aganglionosis, suggesting that Hoxb5 may contribute to the etiology of Hirschsprung's disease.

HOXB5 Protein Profile

Protein Summary

This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in lung and gut development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML) and the occurrence of bronchopulmonary sequestration (BPS) and congenital cystic adenomatoid malformation (CCAM) tissue.

Gene names and symbols associated with Homeobox B5 Proteins (HOXB5)

  • homeo box B5a (hoxb5a)
  • Hox 5 (hox5)
  • homeobox B5 (HOXB5)
  • homeobox B5 (hoxb5)
  • homeobox B5 (LOC100346655)
  • homeo box B5 (Hoxb5)
  • homeobox B5 (Hoxb5)
  • AI385717 protein
  • Ghox-2.1 protein
  • HHO.C10 protein
  • Hox-2.1 protein
  • hox-B5 protein
  • HOX2 protein
  • Hox2.1 protein
  • HOX2A protein
  • Hoxb-5 protein
  • HOXB5 protein
  • hoxb5-A protein
  • HU-1 protein
  • RGD1562292 protein
  • wu:fc38c09 protein
  • XlHbox4 protein
  • z-18 protein
  • ZF-21 protein
  • ZF21 protein

Protein level used designations for Homeobox B5 Proteins (HOXB5)

homeobox b5a , homeobox gene B-5 , homeobox protein Hox-B5a , homeobox protein Zf-21 , Hox 5 , homeobox B5 , homeo box 2A , homeo box B5 , homeobox protein HHO.C10 , homeobox protein Hox-2A , homeobox protein Hox-B5 , homeobox protein Hu-1 , homeobox protein H24.1 , homeobox protein Hox-2.1 , homeobox protein Mu-1 , xhox-1B , xlHbox-4

GENE ID SPECIES
30317 Danio rerio
445674 Ciona intestinalis
696732 Macaca mulatta
749212 Pan troglodytes
100018291 Monodelphis domestica
100113366 Xenopus (Silurana) tropicalis
100346655 Oryctolagus cuniculus
497987 Rattus norvegicus
3215 Homo sapiens
100686000 Canis lupus familiaris
15413 Mus musculus
425096 Gallus gallus
101115382 Ovis aries
378578 Xenopus laevis
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