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HOXB6 is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. Additionally we are shipping HOXB6 Antibodies (56) and many more products for this protein.
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HOXB5 (show HOXB5 Proteins), HOXB6, and HOXB7 (show HOXB7 Proteins) are activated in Barrett esophagus, and the midcluster HOXB gene signature in BE most resembled the colon rather than other GI epithelia.
Data show that inducible Hox (show MSH2 Proteins) genes are selectively sensitive to the inhibition of actin polymerization and that actin polymerization is required for the assembly of a transcription complex on the regulatory region of the Hox (show MSH2 Proteins) genes.
the homeodomain contains most or all of the important structures required for HOXB6 activity in blood cells.
Hoxb6, in skeletal elements at the cervico-thoracic junction, controls multiple independent aspects of skeletal pattern, implicating discrete developmental pathways as substrates for this transcription factor.
These results suggest the requirement of precisely regulated Hoxb6 expression for proper segmentation at tailbud stages.
Overexpression of HOXB6 in marrow progenitors enhances self-renewal and cell growth in vitro. In vivo, it can result in acute myeloid leukemia (show BCL11A Proteins) with a median latency of 223 days.
Altered Hox protein (show HOXA13 Proteins) temporal and cellular balance of expression either contributes to pulmonary hypoplasia or functions as a compensatory mechanism attempting to correct abnormal lung development and maturation in this condition.
This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development, including that of lung and skin, and has been localized to both the nucleus and cytoplasm. Altered expression of this gene or a change in the subcellular localization of its protein is associated with some cases of acute myeloid leukemia and colorectal cancer.
, homeobox gene B-6
, homeobox protein Hox-B6a
, homeobox protein Zf-22
, homeobox B6
, homeo box B6
, homeobox protein Hox-B6
, homeo box 2B
, homeobox protein Hox-2.2
, homeobox protein Hox-2B
, homeobox protein Hu-2
, homeobox protein MH-22A
, homeobox protein Hox-B6-like