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Homeodomain Interacting Protein Kinase 1 Proteins (HIPK1)

The protein encoded by HIPK1 belongs to the Ser/Thr family of protein kinases and HIPK subfamily. Additionally we are shipping HIPK1 Antibodies (59) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HIPK1 204851 Q86Z02
HIPK1 15257 O88904
Rat HIPK1 HIPK1 365895  
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Top HIPK1 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Baculovirus infected Insect Cells Human GST tag   5 μg Log in to see 10 to 12 Days
$322.08
Details

HIPK1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Homeodomain Interacting Protein Kinase 1 (HIPK1) Interaction Partners

Human Homeodomain Interacting Protein Kinase 1 (HIPK1) interaction partners

  1. Analysis of these mutants revealed that HIPK1, HIPK2 (show HIPK2 Proteins) and HIPK3 (show HIPK3 Proteins) but not HIPK4 (show HIPK4 Proteins) are capable of autophosphorylating on other tyrosines

  2. PAGE4 (show PAGE4 Proteins), a regulator of c-Jun (show JUN Proteins) transactivation, is phosphorylated by homeodomain-interacting protein kinase 1.

  3. HIPK1 drives p53 (show TP53 Proteins) activation to limit colorectal cancer cell growth.

  4. HIPK1 and HIPK2 (show HIPK2 Proteins), are transcriptional corepressors that regulate TGF-beta (show TGFB1 Proteins)-dependent angiogenesis during embryonic development.

  5. HIPK1 expression was identified only in invasive breast cancer cells with three different patterns: cytoplasmic, nuclear, and both cytoplasmic and nuclear.

  6. These findings indicate that the control of HIPK1 stability by Mdm2 (show MDM2 Proteins)-NORE1 (show RASSF5 Proteins) has a major effect on cell behaviour, and epigenetic inactivation of NORE1 (show RASSF5 Proteins) enables adenocarcinoma formation in vivo through HIPK1 stabilization.

  7. TNFalpha (show TNF Proteins)-induced desumoylation and cytoplasmic translocation of HIPK1 are critical in TNFalpha (show TNF Proteins)-induced ASK1 (show MAP3K5 Proteins)-JNK (show MAPK8 Proteins)/p38 (show CRK Proteins) activation

  8. c-Myb (show MYB Proteins) appears to be phosphorylated by HIPK1 in its negative regulatory domain as supported by both in vivo and in vitro data.

Mouse (Murine) Homeodomain Interacting Protein Kinase 1 (HIPK1) interaction partners

  1. Therefore, our data confirm that the beta-Catenin (show CTNNB1 Proteins) signaling plays a dual role in controlling cell proliferation/differentiation in the brain and indicate that Hipk1 is the crucial interactor able to revert the outcome of beta-Catenin (show CTNNB1 Proteins) signaling in cells.

  2. Despite the expanded marginal zone B cell population in the HIPK1(-/-) mice, the T-independent type 2 humoral response was impaired.

  3. HIPK1 and Daxx (show DAXX Proteins) collaborate in regulating transcription.

  4. characterization of cells and gene-targeted mice deficient for the p53 (show TP53 Proteins)-binding kinase homeodomain-interacting protein kinase 1

  5. The present study indicated the overlapping roles for Hipk1 and Hipk2 (show HIPK2 Proteins) in mediating cell proliferation and apoptosis in response to morphogenetic and genotoxic signals during mouse development.

  6. SENP1 (show SENP1 Proteins) mediates TNF (show TNF Proteins)-induced desumoylation and translocation of HIPK1, leading to an enhanced ASK1 (show MAP3K5 Proteins)-dependent apoptosis.

Cow (Bovine) Homeodomain Interacting Protein Kinase 1 (HIPK1) interaction partners

  1. TNFalpha (show TNF Proteins)-induced desumoylation and cytoplasmic translocation of HIPK1 are critical in TNFalpha (show TNF Proteins)-induced ASK1 (show MAP3K5 Proteins)-JNK (show MAPK8 Proteins)/p38 (show MAPK14 Proteins) activation

HIPK1 Protein Profile

Protein Summary

The protein encoded by this gene belongs to the Ser/Thr family of protein kinases and HIPK subfamily. It phosphorylates homeodomain transcription factors and may also function as a co-repressor for homeodomain transcription factors. Alternative splicing results in four transcript variants encoding four distinct isoforms.

Gene names and symbols associated with HIPK1

  • homeodomain interacting protein kinase 1 (HIPK1)
  • homeodomain interacting protein kinase 1 (hipk1)
  • homeodomain interacting protein kinase 1 (Hipk1)
  • 1110062K04Rik protein
  • hipk1 protein
  • Myak protein
  • Nbak2 protein

Protein level used designations for HIPK1

homeodomain interacting protein kinase 1 , homeodomain-interacting protein kinase 1-like , homeodomain-interacting protein kinase 1 , homeodomain interacting protein kinase 1-like protein , nuclear body associated kinase 2b , nuclear body-associated kinase 2 , protein kinase Myak

GENE ID SPECIES
100156877 Sus scrofa
100411549 Callithrix jacchus
100545966 Meleagris gallopavo
419880 Gallus gallus
495423 Xenopus laevis
707856 Macaca mulatta
734033 Xenopus (Silurana) tropicalis
743043 Pan troglodytes
100189543 Xenopus laevis
100479410 Ailuropoda melanoleuca
100564191 Anolis carolinensis
204851 Homo sapiens
15257 Mus musculus
365895 Rattus norvegicus
475803 Canis lupus familiaris
512233 Bos taurus
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