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Host Cell Factor C1 (VP16-Accessory Protein) Proteins (HCFC1)

HCFC1 is a member of the host cell factor family and encodes a protein with five Kelch repeats, a fibronectin-like motif, and six HCF repeats, each of which contains a highly specific cleavage signal. Additionally we are shipping HCFC1 Antibodies (35) and HCFC1 Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HCFC1 15161 Q61191
Rat HCFC1 HCFC1 363519  
HCFC1 3054 P51610
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Top HCFC1 Proteins at antibodies-online.com

Showing 3 out of 26 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

HCFC1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,

More Proteins for Host Cell Factor C1 (VP16-Accessory Protein) (HCFC1) Interaction Partners

Mouse (Murine) Host Cell Factor C1 (VP16-Accessory Protein) (HCFC1) interaction partners

  1. survival of the heterozygous Hcfc1(epiKO/+) female embryos llustrates the developmental plasticity of the post-implantation mouse embryo - in this instance, permitting survival of females heterozygous for an X-linked embryonic lethal allele

  2. our work identifies plausible cellular consequences of missense HCFC1 variants and identifies likely and relevant disease mechanisms that converge on embryonic stages of brain development.

  3. These results indicate that HCF-1 represents a novel transcriptional regulator required for maintaining pancreatic b-cell function.

  4. Ronin/Hcf-1 controls a genetic program that contributes to the unimpeded growth of embryonic stem cells.

  5. HCF-1 is an important component of the viral latency-reactivation cycle and it is regulated by association with a component that is distinct from the identified HCF-1 interaction factors

  6. Bap1 (show BAP1 Proteins) helps to control cell proliferation by regulating HCF-1 protein levels and by associating with genes involved in the G(1)-S transition

Human Host Cell Factor C1 (VP16-Accessory Protein) (HCFC1) interaction partners

  1. O-GlcNAcylation of the transcription regulators Host Cell Factor-1 (HCF-1) and Ten-Eleven Translocation protein 2 (TET2) could be readily observed. Our study raises questions on the occurrence and abundance of O-GlcNAcylation as a histone modification

  2. These results demonstrate that distinct OGT (show OGT Proteins)-binding sites in HCF-1 promote proteolysis, and provide novel insights into the mechanism of this unusual protease activity.

  3. our work identifies plausible cellular consequences of missense HCFC1 variants and identifies likely and relevant disease mechanisms that converge on embryonic stages of brain development.

  4. We report here two brothers with dysmorphic features and complex malformations resulting from an X-linked inherited cobalamin deficiency due to HCFC1 gene mutation.

  5. THAP11, ZNF143 (show ZNF143 Proteins), and HCF-1 form a mutually dependent complex on chromatin, which is independent of E2F (show E2F1 Proteins) occupancy.

  6. study reports the tetratricopeptide-repeat domain of O-GlcNAc (show OGT Proteins) transferase binds the carboxyl-terminal portion of an HCF-1 proteolytic repeat such that the cleavage region lies in the glycosyltransferase (show GTDC2 Proteins) active site above uridine diphosphate-GlcNAc; protein glycosylation and HCF-1 cleavage occur in the same active site

  7. A missense mutation in a global transcriptional coregulator, HCFC1, was identified as the genetic basis of an X-linked form of combined methylmalonic acidemia and hyperhomocysteinemia.

  8. HCFC1 is a common component of active human CpG-island promoters and coincides with ZNF143 (show ZNF143 Proteins), THAP11, YY1 (show YY1 Proteins), and GABP transcription factor occupancy.

  9. MLL5 can associate with HCF-1 and then be recruited to E2F1 (show E2F1 Proteins)-responsive promoters to stimulate H3K4 trimethylation and transcriptional activation.

  10. A noncoding, regulatory mutation was identified in the binding site of transcription factor YY1 (show YY1 Proteins) in the HCFC1 gene in patients with nonsyndromic intellectual disability.

Zebrafish Host Cell Factor C1 (VP16-Accessory Protein) (HCFC1) interaction partners

  1. HCFC1 plays a role in craniofacial development, which is in part mediated through the regulation of MMACHC (show MMACHC Proteins) expression

HCFC1 Protein Profile

Protein Summary

This gene is a member of the host cell factor family and encodes a protein with five Kelch repeats, a fibronectin-like motif, and six HCF repeats, each of which contains a highly specific cleavage signal. This nuclear coactivator is proteolytically cleaved at one of the six possible sites, resulting in the creation of an N-terminal chain and the corresponding C-terminal chain. The final form of this protein consists of noncovalently bound N- and C-terminal chains. The protein is involved in control of the cell cycle and transcriptional regulation during herpes simplex virus infection. Alternatively spliced variants which encode different protein isoforms have been described\; however, not all variants have been fully characterized.

Gene names and symbols associated with HCFC1

  • host cell factor C1 (Hcfc1)
  • host cell factor C1 (VP16-accessory protein) (HCFC1)
  • host cell factor C1 (VP16-accessory protein) (Hcfc1)
  • host cell factor C1a (hcfc1a)
  • AW060991 protein
  • CFF protein
  • fc61g09 protein
  • HCF protein
  • HCF-1 protein
  • HCF1 protein
  • hcfc1 protein
  • HFC1 protein
  • im:7159458 protein
  • MRX3 protein
  • RGD1563804 protein
  • VCAF protein
  • wu:fc61g09 protein
  • wu:fj40c12 protein

Protein level used designations for HCFC1

C1 factor , VP16 accessory protein , VP16-accessory protein , host cell factor 1 , HCF , etID52682.11 , host cell factor C1

GENE ID SPECIES
15161 Mus musculus
363519 Rattus norvegicus
3054 Homo sapiens
492246 Canis lupus familiaris
512908 Bos taurus
100328750 Oryctolagus cuniculus
101830931 Mesocricetus auratus
564853 Danio rerio
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