anti-Host Cell Factor C1 (VP16-Accessory Protein) (HCFC1) Antibodies

HCFC1 is a member of the host cell factor family and encodes a protein with five Kelch repeats, a fibronectin-like motif, and six HCF repeats, each of which contains a highly specific cleavage signal. Additionally we are shipping HCFC1 Proteins (28) and HCFC1 Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HCFC1 3054 P51610
HCFC1 15161 Q61191
HCFC1 363519  
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Top anti-HCFC1 Antibodies at antibodies-online.com

Showing 10 out of 41 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using HCFC1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IP, PLA, WB Western Blot: Host Cell Factor 1/HCFC1 Antibody [ABIN2611249] - Samples: Whole cell lysate (5, 15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-HCF1 antibody ABIN2611249 used for WB at 0.04 ug/ml (A) and 1 ug/ml (B) and used for IP at 3 ug/mg lysate. HCF1 was also immunoprecipitated by rabbit anti-HCF1 antibody ABIN2611240, which recognizes a downstream epitope. Detection: Chemiluminescence with exposure times of 30 seconds (A) and 10 seconds (B). 0.1 mL Log in to see 7 to 9 Days
$486.94
Details
Human Rabbit Un-conjugated IP, WB 0.1 mL Log in to see 7 to 9 Days
$486.94
Details
Bat Rabbit Un-conjugated WB 100 μg Log in to see 7 to 9 Days
$493.17
Details
Cow Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of HCFC1 staining in human colon cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of HCFC1 expression in HeLa (A), mouse brain (B) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of jurkat cells, using HCFC1 antibody. 100 μL Log in to see 16 Days
$323.13
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB Immunocytochemistry/Immunofluorescence: HCFC1 Antibody [NBP2-16786] - Immunofluorescence analysis of methanol-fixed HeLa, using antibody at 1:200 dilution. Western Blot: HCFC1 Antibody [NBP2-16786] - Sample (30 ug of whole cell lysate) A: HeLa 5% SDS PAGE gel, diluted at 1:500. 0.1 mL Log in to see 8 to 11 Days
$447.56
Details

HCFC1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , ,


Mouse (Murine) , ,


Rat (Rattus) ,


Top referenced anti-HCFC1 Antibodies

  1. Human Polyclonal HCFC1 Primary Antibody for IP, PLA - ABIN261124 : Parker, Palchaudhuri, Yin, Wei, Chakravarti: A transcriptional regulatory role of the THAP11-HCF-1 complex in colon cancer cell function. in Molecular and cellular biology 2012 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal HCFC1 Primary Antibody for IP, WB - ABIN261125 : Yu, Mashtalir, Daou, Hammond-Martel, Ross, Sui, Hart, Rauscher, Drobetsky, Milot, Shi, Affar: The ubiquitin carboxyl hydrolase BAP1 forms a ternary complex with YY1 and HCF-1 and is a critical regulator of gene expression. in Molecular and cellular biology 2010 (PubMed)

More Antibodies against HCFC1 Interaction Partners

Human Host Cell Factor C1 (VP16-Accessory Protein) (HCFC1) interaction partners

  1. Data show that Myc (show MYC Antibodies) boxes (MbIV) is required for the association of MYC (show MYC Antibodies) with the abundant transcriptional coregulator host cell factor-1 (HCF-1).

  2. The M4 motif (ACTAYRNNNCCCR) is a functional regulatory bipartite cis (show CISH Antibodies)-element, which engages a THAP11 (show THAP11 Antibodies)/HCF-1 complex via binding to the ACTAYR module, while the CCCRRNRNRC subsequence part constitutes a binding platform for Ikaros (show IKZF1 Antibodies) and NFKB1 (show NFKB1 Antibodies)

  3. Beyond its well-known role in adding beta-O-GlcNAc (show OGT Antibodies) to serine and threonine residues of nuclear and cytoplasmic proteins, OGT (show OGT Antibodies) also acts as a protease in the maturation of the cell cycle regulator (show CDKN2A Antibodies), HCF-1, and serves as an integral member of several protein complexes, many of them linked to gene expression. (Review)

  4. findings show that cellular factors OCT2 and HCF1 bind OriP in association with Epstein-Barr virus nuclear antigen 1 to maintain elevated histone H3K4me3 and transcriptional enhancer function

  5. O-GlcNAcylation of the transcription regulators Host Cell Factor-1 (HCF-1) and Ten-Eleven Translocation protein 2 (TET2 (show TET2 Antibodies)) could be readily observed. Our study raises questions on the occurrence and abundance of O-GlcNAcylation as a histone modification

  6. These results demonstrate that distinct OGT (show OGT Antibodies)-binding sites in HCF-1 promote proteolysis, and provide novel insights into the mechanism of this unusual protease activity.

  7. our work identifies plausible cellular consequences of missense HCFC1 variants and identifies likely and relevant disease mechanisms that converge on embryonic stages of brain development.

  8. We report here two brothers with dysmorphic features and complex malformations resulting from an X-linked inherited cobalamin deficiency due to HCFC1 gene mutation.

  9. THAP11 (show THAP11 Antibodies), ZNF143 (show ZNF143 Antibodies), and HCF-1 form a mutually dependent complex on chromatin, which is independent of E2F (show E2F1 Antibodies) occupancy.

  10. study reports the tetratricopeptide-repeat domain of O-GlcNAc (show OGT Antibodies) transferase binds the carboxyl-terminal portion of an HCF-1 proteolytic repeat such that the cleavage region lies in the glycosyltransferase (show GTDC2 Antibodies) active site above uridine diphosphate-GlcNAc; protein glycosylation and HCF-1 cleavage occur in the same active site

Mouse (Murine) Host Cell Factor C1 (VP16-Accessory Protein) (HCFC1) interaction partners

  1. male epiblast-specific loss of Hcfc1 leads to a developmental arrest at E6.5 with a rapid progressive cell-cycle exit and an associated failure of anterior visceral endoderm migration and primitive streak formation.

  2. Beyond its well-known role in adding beta-O-GlcNAc to serine and threonine residues of nuclear and cytoplasmic proteins, OGT (show OGT Antibodies) also acts as a protease in the maturation of the cell cycle regulator (show CDKN2A Antibodies), HCF-1, and serves as an integral member of several protein complexes, many of them linked to gene expression. (Review)

  3. survival of the heterozygous Hcfc1(epiKO/+) female embryos llustrates the developmental plasticity of the post-implantation mouse embryo - in this instance, permitting survival of females heterozygous for an X-linked embryonic lethal allele

  4. our work identifies plausible cellular consequences of missense HCFC1 variants and identifies likely and relevant disease mechanisms that converge on embryonic stages of brain development.

  5. These results indicate that HCF-1 represents a novel transcriptional regulator required for maintaining pancreatic b-cell function.

  6. Ronin (show THAP11 Antibodies)/Hcf-1 controls a genetic program that contributes to the unimpeded growth of embryonic stem cells.

  7. HCF-1 is an important component of the viral latency-reactivation cycle and it is regulated by association with a component that is distinct from the identified HCF-1 interaction factors

  8. Bap1 (show BAP1 Antibodies) helps to control cell proliferation by regulating HCF-1 protein levels and by associating with genes involved in the G(1)-S transition

Zebrafish Host Cell Factor C1 (VP16-Accessory Protein) (HCFC1) interaction partners

  1. HCFC1 plays a role in craniofacial development, which is in part mediated through the regulation of MMACHC (show MMACHC Antibodies) expression

HCFC1 Antigen Profile

Protein Summary

This gene is a member of the host cell factor family and encodes a protein with five Kelch repeats, a fibronectin-like motif, and six HCF repeats, each of which contains a highly specific cleavage signal. This nuclear coactivator is proteolytically cleaved at one of the six possible sites, resulting in the creation of an N-terminal chain and the corresponding C-terminal chain. The final form of this protein consists of noncovalently bound N- and C-terminal chains. The protein is involved in control of the cell cycle and transcriptional regulation during herpes simplex virus infection. Alternatively spliced variants which encode different protein isoforms have been described\; however, not all variants have been fully characterized.

Gene names and symbols associated with HCFC1

  • host cell factor C1 (VP16-accessory protein) (HCFC1) antibody
  • host cell factor C1 (Hcfc1) antibody
  • host cell factor C1a (hcfc1a) antibody
  • host cell factor C1 (AaeL_AAEL008905) antibody
  • host cell factor C1 (CpipJ_CPIJ014908) antibody
  • host cell factor C1 (HCFC1) antibody
  • host cell factor C1 (VP16-accessory protein) (Hcfc1) antibody
  • AW060991 antibody
  • CFF antibody
  • fc61g09 antibody
  • HCF antibody
  • HCF-1 antibody
  • HCF1 antibody
  • HCFC1 antibody
  • HFC1 antibody
  • im:7159458 antibody
  • MRX3 antibody
  • RGD1563804 antibody
  • VCAF antibody
  • wu:fc61g09 antibody
  • wu:fj40c12 antibody

Protein level used designations for HCFC1

C1 factor , HCF , VP16 accessory protein , host cell factor 1 , VP16-accessory protein , etID52682.11 , host cell factor C1

GENE ID SPECIES
3054 Homo sapiens
15161 Mus musculus
363519 Rattus norvegicus
564853 Danio rerio
5571204 Aedes aegypti
6048549 Culex quinquefasciatus
100137257 Papio anubis
100328750 Oryctolagus cuniculus
492246 Canis lupus familiaris
512908 Bos taurus
101830931 Mesocricetus auratus
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