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anti-HtrA Serine Peptidase 1 (HTRA1) Antibodies

HTRA1 encodes a member of the trypsin family of serine proteases. Additionally we are shipping HtrA Serine Peptidase 1 Kits (20) and HtrA Serine Peptidase 1 Proteins (19) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HTRA1 5654 Q92743
HTRA1 56213 Q9R118
HTRA1 65164 Q9QZK5
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Top anti-HtrA Serine Peptidase 1 Antibodies at antibodies-online.com

Showing 10 out of 63 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB Formalin-fixed and paraffin-embedded human cancer tissue reacted with ... HtrA1-K396 (ABIN388128) western blot analysis in Hela cell line lysate... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IF, IHC (p), WB The anti-HtrA1 N-term Pab (ABIN388127) is used in Western blot to dete... HtrA1 Antibody (N-term) (ABIN388127)immunohistochemistry analysis in f... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 14 Days
$527.15
Details
Human Rabbit Biotin IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 8 to 10 Days
$507.83
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IF, IHC, WB   200 μL Log in to see 8 to 10 Days
$713.17
Details

HTRA1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,
,
Mouse (Murine) , , ,

Rat (Rattus) ,

Top referenced anti-HtrA Serine Peptidase 1 Antibodies

  1. Human Polyclonal HTRA1 Primary Antibody for IHC (p), WB - ABIN388128 : Chamberland, Wang, Jones, Collins-Racie, LaVallie, Huang, Liu, Morris, Flannery, Yang: Identification of a novel HtrA1-susceptible cleavage site in human aggrecan: evidence for the involvement of HtrA1 in aggrecan proteolysis in vivo. in The Journal of biological chemistry 2009 (PubMed)
    Show all 5 references for ABIN388128

  2. Human Polyclonal HTRA1 Primary Antibody for IF, IHC (p) - ABIN388127 : Hu, Carozza, Klein, Nantermet, Luk, Crowl: Human HtrA, an evolutionarily conserved serine protease identified as a differentially expressed gene product in osteoarthritic cartilage. in The Journal of biological chemistry 1999 (PubMed)
    Show all 5 references for ABIN388127

  3. Human Polyclonal HTRA1 Primary Antibody for EIA, WB - ABIN356843 : Howes, Lerch, Greenhalf, Stocken, Ellis, Simon, Truninger, Ammann, Cavallini, Charnley, Uomo, Delhaye, Spicak, Drumm, Jansen, Mountford, Whitcomb, Neoptolemos: Clinical and genetic characteristics of hereditary pancreatitis in Europe. in Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2004 (PubMed)
    Show all 3 references for ABIN356843

  4. Human Polyclonal HTRA1 Primary Antibody for EIA, IHC (p) - ABIN356844 : Chien, Staub, Hu, Erickson-Johnson, Couch, Smith, Crowl, Kaufmann, Shridhar: A candidate tumor suppressor HtrA1 is downregulated in ovarian cancer. in Oncogene 2004 (PubMed)
    Show all 3 references for ABIN356844

More Antibodies against HtrA Serine Peptidase 1 Interaction Partners

Zebrafish HtrA Serine Peptidase 1 (HTRA1) interaction partners

  1. HtrA1 is indispensable for dorsoventral patterning in early zebrafish embryogenesis and serves as a key upstream regulator of FGF signaling through the control of FGF levels.

Rhesus Monkey HtrA Serine Peptidase 1 (HTRA1) interaction partners

  1. Our data point to a yet unexpected effect of decreased HTRA1 expression on drusen pathogenesis. Thus not only a higher HTRA1 expression, but an imbalance of HTRA1 might be disease-relevant.

  2. Tests for association revealed a variant in the promoter region of HTRA1 and two variants in the 5'-UTR (show UTS2R Antibodies) of ARMS2 (show ARMS2 Antibodies) to be associated with drusen.

  3. As in humans, one variant within LOC387715/ARMS2 (show ARMS2 Antibodies) and one in HTRA1 were significantly associated with age-related macular degeneration.

Human HtrA Serine Peptidase 1 (HTRA1) interaction partners

  1. significant increase of serum HtrA1 in early-onset pre-eclampsia

  2. a frameshift mutation in the HTRA1 gene detected in a CARASIL pedigree resulted in reduced HTRA1 protein and increased TGF-beta1 (show TGFB1 Antibodies) expression, which may cause severe CARASIL and peripheral small arterial disease

  3. Human HTRA1 expression is enhanced by Age-related macular degeneration specific indel mutation in the promoter region of HTRA1 gene, and this enhanced HTRA1 may be concerned with induce retinal neovasucularization.

  4. Results does not conclusively support HTRA1 role as a tumor suppressor but suggest its possible prognostic role in many human tumors.

  5. Studies indicate that the high-risk allele of the 10q26 locus encompasses three genes, PLEKHA1 (show PLEKHA1 Antibodies), ARMS2 (show ARMS2 Antibodies), and HTRA1 with high linkage disequilibrium.

  6. Low HtrA1 expression is associated with gastric cancer.

  7. HtrA1 expression was closely related to EMT (show ITK Antibodies), which might be a potential mechanism underlying metastasis of HCC (show FAM126A Antibodies)

  8. Low HtrA1 expression is significantly related to breast cancer poor prognosis parameters, and HtrA1 loss in sentinel nodes is related to metastasis of non sentinel nodes.

  9. It was concluded that high expression of HtrA1 could significantly reverse multidrug resistance of hepatoma cells by targeting XIAP (show XIAP Antibodies).

  10. The growth of choroidal neovascularization in AMD (show AMD1 Antibodies) would be affected by 2 genes: MMP20 (show MMP20 Antibodies), a newly confirmed gene expressed in the retina, and ARMS2 (show ARMS2 Antibodies)/HTRA1, a well-known susceptibility gene for AMD (show AMD1 Antibodies).

Mouse (Murine) HtrA Serine Peptidase 1 (HTRA1) interaction partners

  1. Increased expressions of Tgf-beta1 (show TGFB1 Antibodies), p-Smad2 (show SMAD2 Antibodies)/3 and HtrA1 were detected in the articular chondrocytes of knee joints in models of osteoarthritis.

  2. In mouse brain tissue and embryonic fibroblasts there is a facilitating role of HtrA1 in TGF-beta (show TGFB1 Antibodies) pathway activation.

  3. HtrA1 plays important roles in the differentiation of trophoblasts from Tpbpa-positive precursors in the ectoplacental cone

  4. The HtrA1 overexpression and mainstream cigarette smoke can independently lead to CNV. The HtrA1 gene is a strong risk factor for wet AMD (show AMD1 Antibodies)

  5. the inhibitory effect of IFN-gamma (show IFNG Antibodies) on HTRA1 expression was evidenced in collagen-induced arthritis (CIA (show NCOA5 Antibodies)) mouse models and in human RA synovial cells.

  6. Serine protease HTRA1 antagonizes transforming growth factor-beta signaling by cleaving its receptors and loss of HTRA1 in vivo enhances bone formation.

  7. Data show that HtrA1 is produced during osteoclastogenesis, and negatively regulates osteoblast differentiation, osteoblast differentiation and BMP2 (show BMP2 Antibodies)-induced Smad1 (show SMAD1 Antibodies)/5/8, ERK1/2 (show MAPK1/3 Antibodies) and p38 (show CRK Antibodies) phosphorylation in pre-osteoblasts.

  8. This study offers new insights into the regulation of HTRA-1 expression via LPS (show TLR4 Antibodies)/TLR-4 (show TLR4 Antibodies) and the role of HTRA-1 in rheumatoid arthrisis pathogenesis.

  9. suggest a critical role for LRP1 (show LRP1 Antibodies) in maintaining the integrity of vessels by regulating protease activity as well as matrix deposition by modulating HtrA1 and connective tissue growth factor (show CTGF Antibodies) protein levels.

  10. a critical role of HTRA1 in the regulation of angiogenesis via TGF-beta (show TGFB1 Antibodies) signaling and identified GDF6 (show GDF6 Antibodies) as a novel disease gene for AMD (show AMD1 Antibodies).

Xenopus laevis HtrA Serine Peptidase 1 (HTRA1) interaction partners

  1. The results are consistent with a mechanism by which xHtrA1, through cleaving proteoglycans, releases cell-surface-bound Fibroblast Growth Factors (FGF) ligands and stimulates long-range FGF signaling.

HtrA Serine Peptidase 1 (HTRA1) Antigen Profile

Protein Summary

This gene encodes a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth. Variations in the promoter region of this gene are the cause of susceptibility to age-related macular degeneration type 7.

Gene names and symbols associated with HTRA1

  • HtrA serine peptidase 1a (htra1a) antibody
  • HtrA serine peptidase 1 (HTRA1) antibody
  • HtrA serine peptidase 1b (htra1b) antibody
  • HtrA serine peptidase 1 (htra1) antibody
  • Serine protease HTRA1 (htra1) antibody
  • HtrA serine peptidase 1 (Htra1) antibody
  • serine protease (HTRA) antibody
  • AI429470 antibody
  • ARMD7 antibody
  • CARASIL antibody
  • HTRA antibody
  • HTRA1 antibody
  • L56 antibody
  • MGC145723 antibody
  • ORF480 antibody
  • Prss11 antibody
  • RSPP11 antibody
  • Xhtra1 antibody
  • zgc:92029 antibody
  • zgc:172061 antibody

Protein level used designations for HTRA1

HtrA serine peptidase 1 , high-temperature requirement A serine peptidase 1A , serine protease 11 , serine protease HTRA1A , high-temperature requirement A serine peptidase 1B , serine protease HTRA1B , high temperature required A1 , Serine protease HTRA1 , IGFBP5-protease , high-temperature requirement A serine peptidase 1 , protease, serine, 11 (IGF binding) , serine protease HTRA1 , insulin-like growth factor binding protein 5 protease , protease, serine, 11 (Igf binding) , IGF binding , protease, serine, 11 , protease serine 11 , High-temperature requirement A serine peptidase 1 , Serine protease 11

GENE ID SPECIES
431766 Danio rerio
450792 Pan troglodytes
565082 Danio rerio
705855 Macaca mulatta
780187 Xenopus (Silurana) tropicalis
100064570 Equus caballus
100196695 Salmo salar
100541363 Meleagris gallopavo
100564246 Anolis carolinensis
100583976 Nomascus leucogenys
5654 Homo sapiens
56213 Mus musculus
477852 Canis lupus familiaris
282326 Bos taurus
65164 Rattus norvegicus
496061 Xenopus laevis
100857572 Gallus gallus
100008705 Oryctolagus cuniculus
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