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Huntingtin Associated Protein 1 (HAP1) ELISA Kits

Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. Additionally we are shipping HAP1 Antibodies (88) and HAP1 Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse HAP1 HAP1 11792 P28352
HAP1 9001 P54257
Anti-Rat HAP1 HAP1 29430 P54256
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Top HAP1 ELISA Kits at

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Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 15.6 pg/mL 62.5-4000 pg/mL Typical standard curve 96 Tests Log in to see 11 to 13 Days

More ELISA Kits for HAP1 Interaction Partners

Mouse (Murine) Huntingtin Associated Protein 1 (HAP1) interaction partners

  1. Is closely associated with upregulation of the Ref1 (show THOC4 ELISA Kits)/Nrf2 (show NFE2L2 ELISA Kits) signalling pathway.

  2. Results show the stimulatory effect of PARP-1 (show PARP1 ELISA Kits) on APE1 (show APEX1 ELISA Kits)-dependent base excision repair (BER). PARP-1 (show PARP1 ELISA Kits) and APE1 (show APEX1 ELISA Kits) appear to have a functional interaction in BER since PARP-1 (show PARP1 ELISA Kits) can stimulate the strand incision activity of APE1 (show APEX1 ELISA Kits).

  3. Early loss of Hap1 significantly reduces postnatal hippocampal neurogenesis, and leads to adult depressive-like behavior.

  4. Hap1 interacts with Bcr (show BCR ELISA Kits) on microtubules to regulate neuronal differentiation.

  5. increases in APEX1 (show APEX1 ELISA Kits) level confer protection against the murine paternal age effect, thus highlighting the role of APEX1 (show APEX1 ELISA Kits) in preserving reproductive health with increasing age and in protection against genotoxin-induced mutagenesis in somatic cells

  6. Endothelial cell tumor proliferation was found to be dependent on Apex-1 (show APEX1 ELISA Kits) expression.

  7. Expression of OGG1 (show OGG1 ELISA Kits) and APEX1 (show APEX1 ELISA Kits) was decreased at 3h after last exposure to Aroclor 1254 and only the expression level of APEX1 (show APEX1 ELISA Kits) was recovered at 24-h after, so inhibition of DNA repair can be a potential mode of action of Aroclor 1254 gonadal toxicity.

  8. Data indicate that the endonuclease activity of APE1 is required for class switch recombination (CSR).

  9. These results suggest that mitochondrial APE1/Ref-1 (show APEX1 ELISA Kits) is contributed to the protective role to protein kinase C (show PKC ELISA Kits)-induced mitochondrial dysfunction in endothelial cells.

  10. Spinal motor neurones down-regulate APE1 (show APEX1 ELISA Kits) upon oxidative stress. This property renders motor neurones susceptible to continuous challenge of oxidative stress in pathological conditions.

Human Huntingtin Associated Protein 1 (HAP1) interaction partners

  1. data fully support that HAP1 (show APEX1 ELISA Kits) is a GKAP (show DLGAP1 ELISA Kits), anchoring specifically to the cGMP-dependent protein kinase (show CDK7 ELISA Kits) isoform Ibeta, and provide further evidence that also PKG (show PRKG1 ELISA Kits) spatiotemporal signaling is largely controlled by anchoring proteins

  2. HAP1 (show APEX1 ELISA Kits) gene expression is related to the radiosensitivity of breast cancer cells and may play an important role in the regulation of cellular radiosensitivity

  3. Overexpression of HAP1 (show APEX1 ELISA Kits) reduced in vitro cell growth in breast cancer cell lines.

  4. The results of this study found no association was found between the HAP1 (show APEX1 ELISA Kits) T441M polymorphism and the age at onset of Huntington's disease .

  5. The results of this study suggested that HAP1 (show APEX1 ELISA Kits) co-localizes and associates with APP (show APP ELISA Kits) in physiological conditions of mouse and human brain.

  6. WT HTT (show HTT ELISA Kits) regulates ciliogenesis by interacting through huntingtin-associated protein 1 (HAP1) with pericentriolar material 1 protein (PCM1 (show PCM1 ELISA Kits)).

  7. HAP1 (show APEX1 ELISA Kits)/stigmoid body interacts with the normal ataxin-3 (show ATXN3 ELISA Kits) through Josephin (show ATXN3 ELISA Kits) domain

  8. sortilin (show SORT1 ELISA Kits) stabilizes the proBDNF.HAP1 complex

  9. ADORA2A (show ADORA2A ELISA Kits), but not HAP1 (show APEX1 ELISA Kits) or OGG1 (show OGG1 ELISA Kits), may have a role in age at onset in Huntington's disease

  10. REVIEW: function of HAP1 (show APEX1 ELISA Kits)

HAP1 Antigen Profile

Antigen Summary

Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene names and symbols associated with HAP1

  • apurinic/apyrimidinic endonuclease 1 (Apex1) antibody
  • huntingtin-associated protein 1 (HAP1) antibody
  • huntingtin-associated protein 1 (Hap1) antibody
  • APE antibody
  • Apex antibody
  • HAP-1 antibody
  • HAP1 antibody
  • HAP1-A antibody
  • HAP1-B antibody
  • HAP2 antibody
  • hHLP1 antibody
  • HIP5 antibody
  • HLP antibody
  • Ref-1 antibody

Protein level used designations for HAP1

AP endonuclease 1 , APEN , APEX nuclease , DNA-(apurinic or apyrimidinic site) lyase , apurinic-apyrimidinic endonuclease 1 , redox factor-1 , HAP-1 , huntingtin-associated protein 2 , neuroan 1 , huntingtin-associated protein 1 (neuroan 1)

11792 Mus musculus
9001 Homo sapiens
15114 Mus musculus
29430 Rattus norvegicus
607751 Canis lupus familiaris
618422 Bos taurus
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