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Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 7 Proteins (HSD3B7)

HSD3B7 encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. Additionally we are shipping Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 7 Antibodies (42) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HSD3B7 80270 Q9H2F3
HSD3B7 101502 Q9EQC1
Rat HSD3B7 HSD3B7 246211 O35048
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Top Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 7 Proteins at antibodies-online.com

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
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Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
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HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
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HSD3B7 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 7 (HSD3B7) Interaction Partners

Human Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 7 (HSD3B7) interaction partners

  1. Expression of steroid sulfated (show SULF1 Proteins) transporters and 3beta-HSD (show CHST3 Proteins) activity in endometrium of polycystic ovary syndrome

  2. Homozygosity mapping identifies a bile acid biosynthetic defect (3beta-HSD (show CHST3 Proteins) deficiency due to a frameshift mutation in HSD3B7) in an adult with cirrhosis of unknown etiology.

  3. Mutations in the HSD3B7 gene account for autosomal recessive neonatal cholestasis caused by 3[beta]-hydroxy-[DELTA]5-C27-steroid dehydrogenase (show HSD17B12 Proteins)/isomerase deficiency.

Mouse (Murine) Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 7 (HSD3B7) interaction partners

  1. Findings indicate that CYP7B1 (show CYP7B1 Proteins) and HSD3B7, as well as CH25H (show CH25H Proteins), have essential roles in controlling oxysterol production in lymphoid tissues.

  2. Catalyzes two reactions required for inversion of the cholesterol 3beta-hydroxyl group to the 3alpha-hydroxyl of bile acids; its stereochemical alteration eliminates cholesterol absorption in the gut (show GUSB Proteins) and enterohepatic circulation feedback regulation.

Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 7 (HSD3B7) Protein Profile

Protein Summary

This gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this gene are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with HSD3B7

  • hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 (HSD3B7)
  • hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 (Hsd3b7)
  • AI195443 protein
  • BB098564 protein
  • CBAS1 protein
  • Cca2 protein
  • PFIC4 protein
  • SDR11E3 protein

Protein level used designations for HSD3B7

3 beta-hydroxy-delta 5-C27-steroid oxidoreductase , 3 beta-hydroxysteroid dehydrogenase type 7 , 3 beta-hydroxysteroid dehydrogenase type VII , 3-beta-HSD VII , 3-beta-hydroxy-Delta(5)-C27 steroid oxidoreductase , C(27)-3BETA-HSD , c(27) 3-beta-HSD , cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase , short chain dehydrogenase/reductase family 11E, member 3 , confluent 3Y1 cell-associated 2

GENE ID SPECIES
80270 Homo sapiens
101502 Mus musculus
246211 Rattus norvegicus
100525281 Sus scrofa
540229 Bos taurus
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