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anti-Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10) Antibodies

HSD17B10 encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. Additionally we are shipping HSD17B10 Proteins (18) and HSD17B10 Kits (13) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HSD17B10 3028 Q99714
HSD17B10 15108  
HSD17B10 63864 O70351
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Top anti-HSD17B10 Antibodies at antibodies-online.com

Showing 10 out of 111 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry on Formalin-fixed and paraffin-embedded human prostate tissue. (Top)Coloration with the Anti-ABAD antibody at a 1:20 concentration. (Bottom)Antibody adsorbed to the antigen (peptide), negative control.Disappearance of cytoplasmic staining indicating the antibody is specific. Western blot analysis of anti-ABAD Pab in mouse kidney tissue lysate.ABAD(arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-ABAD Pab (ABIN390286) in mouse kidney tissue lysate.ABAD(arrow) was detected using the purified polyclonal antibody. Immunohistochemistry on Formalin-fixed and paraffin-embedded human prostate tissue. (Top)Coloration with the Anti-ABAD antibody at a 1:20 concentration. (Bottom)Antibody adsorbed to the antigen (peptide), negative control.Disappearance of cytoplasmic staining indicating the antibody is specific. Data and protocol courtesy of Marie-Hélène Levesque, Centre de Recherche du CHUL, Canada. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated ELISA, WB ABIN185330 staining (0.3µg/ml) of Human Brain lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Cow Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated IHC (p) 7 mL Log in to see 2 to 3 Days
$226.00
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
$253.00
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from LOVO cells, using ERAB Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain tissue, using ERAB Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB IHC-P Image ERAB antibody detects ERAB protein at mitochondria on mouse intestine by immunohistochemical analysis. Sample: Paraffin-embedded mouse intestine. ERAB antibody , dilution: 1:500. WB Image Sample (30 ug of whole cell lysate)    A: PC-12   12% SDS PAGE    antibody diluted at 1:5000   100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Mouse Un-conjugated IF, WB Western Blot analysis of HSD17B10 expression in transfected 293T cell line by HSD17B10 MaxPab polyclonal antibody.Lane 1: HADH2 transfected lysate(28.71 KDa).Lane 2: Non-transfected lysate. Immunofluorescence of purified MaxPab antibody to HADH2 on HeLa cell. [antibody concentration 10 ug/ml] 50 μL Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IHC (p), WB Anti- ERAB Picoband antibody,IHC(P) IHC(P): Human Mammary Cancer Tissue 100 μg Log in to see 4 to 6 Days
$240.00
Details

HSD17B10 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Mouse (Murine)
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Rat (Rattus)
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Top referenced anti-HSD17B10 Antibodies

  1. Human Polyclonal HSD17B10 Primary Antibody for EIA, IHC (p) - ABIN358845 : Takuma, Yao, Huang, Xu, Chen, Luddy, Trillat, Stern, Arancio, Yan: ABAD enhances Abeta-induced cell stress via mitochondrial dysfunction. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005 (PubMed)
    Show all 5 references for ABIN358845

  2. Human Polyclonal HSD17B10 Primary Antibody for ELISA, WB - ABIN185330 : He, Schulz, Yang: A human brain L-3-hydroxyacyl-coenzyme A dehydrogenase is identical to an amyloid beta-peptide-binding protein involved in Alzheimer's disease. in The Journal of biological chemistry 1998 (PubMed)
    Show all 4 references for ABIN185330

  3. Human Polyclonal HSD17B10 Primary Antibody for IHC (p), WB - ABIN390286 : He, Merz, Mehta, Schulz, Yang: Human brain short chain L-3-hydroxyacyl coenzyme A dehydrogenase is a single-domain multifunctional enzyme. Characterization of a novel 17beta-hydroxysteroid dehydrogenase. in The Journal of biological chemistry 1999 (PubMed)
    Show all 2 references for ABIN390286

  4. Human Polyclonal HSD17B10 Primary Antibody for WB - ABIN871705 : Holzmann, Frank, Löffler, Bennett, Gerner, Rossmanith: RNase P without RNA: identification and functional reconstitution of the human mitochondrial tRNA processing enzyme. in Cell 2008 (PubMed)

  5. Human Polyclonal HSD17B10 Primary Antibody for IF, WB - ABIN516335 : Kristofiková, Bocková, Hegnerová, Bartos, Klaschka, Rícný, Rípová, Homola: Enhanced levels of mitochondrial enzyme 17beta-hydroxysteroid dehydrogenase type 10 in patients with Alzheimer disease and multiple sclerosis. in Molecular bioSystems 2009 (PubMed)

More Antibodies against HSD17B10 Interaction Partners

Human Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10) interaction partners

  1. Data suggest that HSD10 plays a role in alterations of energy metabolism by regulating mtDNA content in colorectal carcinomas.

  2. upon exposure to E2, ERalpha (show ESR1 Antibodies) rapidly localizes to mitochondria, in which it interacts with HSD17B10 to modulate the expression of mitochondrial RNA transcripts.

  3. Our findings demonstrate that overexpression of HSD10 accelerates pheochromocytoma cell growth, enhances cell respiration, and increases cellular resistance to cell death induction.

  4. Three HSD10 variants associated with neurodegenerative disorders are inactive with cardiolipin

  5. The authors demonstrate elevated amounts of unprocessed pre-tRNAs and mRNA transcripts encoding mitochondrial subunits indicating deficient RNase P activity in HSD10 disease.

  6. The study showed that pathogenic mutations impair SDR5C1-dependent dehydrogenation, tRNA processing and methylation.

  7. loss of HSD10 causes impaired mitochondrial precursor transcript processing which may explain mitochondrial dysfunction observed in HSD10 disease

  8. Defects in this gene are a cause of 17beta-hydroxysteroid dehydrogenase (show HSD17B7 Antibodies) type 10 (HSD10) deficiency. The encoded protein does not exhibit generalized alcohol dehydrogenase (show AKR1A1 Antibodies) activity as was previously thought.

  9. Significantly higher levels of SRD5A1 (show SRD5A1 Antibodies), AKR1C2 (show AKR1C2 Antibodies), AKR1C3 (show AKR1C3 Antibodies), and HSD17B10 mRNA were however found in bone metastases than in non-malignant and/or malignant prostate tissue

  10. Inhibition of mitochondrial RNase P by beta-amyloid is an unspecific effect and is not mediated by beta-amyloid interaction with SDR5C1.

Mouse (Murine) Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10) interaction partners

  1. that 17beta-HSD-10 is a major product of both fetal and adult-type Leydig cells.

  2. ABAD enhances Abeta (show APP Antibodies)-induced cell stress via mitochondrial dysfunction.Amyloid-beta peptide (Abeta (show APP Antibodies)) binding alcohol dehydrogenase (show AKR1A1 Antibodies) (ABAD), an enzyme present in neuronal mitochondria, is a cofactor facilitating Abeta (show APP Antibodies)-induced cell stress.

HSD17B10 Antigen Profile

Protein Summary

This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein has been implicated in the development of Alzheimer's disease, and mutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.

Gene names and symbols associated with HSD17B10

  • hydroxysteroid (17-beta) dehydrogenase 10 (HSD17B10) antibody
  • hydroxysteroid (17-beta) dehydrogenase 10 (hsd17b10) antibody
  • hydroxysteroid (17-beta) dehydrogenase 10 (LOC100342235) antibody
  • hydroxysteroid (17-beta) dehydrogenase 10 (Hsd17b10) antibody
  • 17b-HSD10 antibody
  • 17bHSD10 antibody
  • ABAD antibody
  • Ads9 antibody
  • CAMR antibody
  • DUPXp11.22 antibody
  • ERAB antibody
  • Hadh2 antibody
  • HCD2 antibody
  • hsd10 antibody
  • HSD17B10 antibody
  • im:6899159 antibody
  • MHBD antibody
  • MRPP2 antibody
  • MRX17 antibody
  • MRX31 antibody
  • MRXS10 antibody
  • SCHAD antibody
  • SDR5C1 antibody
  • wu:fj61f03 antibody
  • zgc:101605 antibody

Protein level used designations for HSD17B10

hydroxysteroid (17-beta) dehydrogenase 10 , 3-hydroxyacyl-CoA dehydrogenase type-2 , hydroxyacyl-Coenzyme A dehydrogenase, type II , 3-hydroxy-2-methylbutyryl-CoA dehydrogenase , AB-binding alcohol dehydrogenase , amyloid-beta peptide binding alcohol dehydrogenase , endoplasmic reticulum-associated amyloid beta-peptide-binding protein , mitochondrial RNase P subunit 2 , mitochondrial ribonuclease P protein 2 , short chain L-3-hydroxyacyl-CoA dehydrogenase type 2 , short chain dehydrogenase/reductase family 5C, member 1 , short chain type dehydrogenase/reductase XH98G2 , 17-beta-HSD 10 , 17-beta-hydroxysteroid dehydrogenase 10 , 3-hydroxyacyl-CoA dehydrogenase type II , hydroxyacyl-Coenzyme A dehydrogenase type II , mitochondrial RNase P protein 2 , type II HADH , amyloid beta-peptide binding protein , short chain L-3-hydroxyacyl-CoA dehydrogenase , hydroxyacyl-Coenzyme A dehydrogenase, type II hydroxyacyl-Coenzyme A

GENE ID SPECIES
425758 Gallus gallus
450078 Danio rerio
549265 Xenopus (Silurana) tropicalis
465649 Pan troglodytes
480930 Canis lupus familiaris
100342235 Oryctolagus cuniculus
3028 Homo sapiens
446903 Xenopus laevis
15108 Mus musculus
63864 Rattus norvegicus
281809 Bos taurus
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