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IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 Proteins (IMPDH2)

IMPDH2 encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. Additionally we are shipping IMPDH2 Antibodies (75) and IMPDH2 Kits (5) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
IMPDH2 3615 P12268
IMPDH2 301005  
IMPDH2 23918 P24547
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Top IMPDH2 Proteins at antibodies-online.com

Showing 9 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 7 to 8 Days
$407.00
Details
HOST_Escherichia coli (E. coli) Human GST tag 1 mg Log in to see 7 to 9 Days
$1,842.50
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,457.67
Details
HOST_Escherichia coli (E. coli) Human His tag   50 μg Log in to see 5 Days
$385.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 3 to 4 Days
$498.21
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

IMPDH2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Rat (Rattus)

Mouse (Murine)

Top referenced IMPDH2 Proteins

  1. Human IMPDH2 Protein expressed in Escherichia coli (E. coli) - ABIN667973 : Bremer, Mandla, Vethe, Rasmussen, Rootwelt, Line, Midtvedt, Bergan: Expression of IMPDH1 and IMPDH2 after transplantation and initiation of immunosuppression. in Transplantation 2008 (PubMed)
    Show all 2 references for ABIN667973

More Proteins for IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2) Interaction Partners

Human IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2) interaction partners

  1. The findings suggest that overexpressed IMPDH2 can be used as a biomarker for kidney and bladder cancer diagnosis and is a potential therapeutic target for the diseases

  2. IMPDH2 is directly involved in the development of chemoresistance and radioresistance in osteosarcoma cells.

  3. Compared with non-cancerous prostate tissues, IMPDH2 mRNA and protein expression levels were both significantly upregulated in prostate cancer tissues.

  4. the localization of IMPDH2 inside the nucleus of human cells as well as the ultrastructure of R&R inclusions

  5. Rods and rings (RR) are protein assemblies composed of CTPS1 and IMPDH2. Glutamine deprivation initiates reversible assembly of mammalian rods and rings.

  6. Anti-IMPDH2 may cause difficulties in interpretation of immunofluorescence patterns in routine autoantibody testing.

  7. IMPDHII plays an important role in the negative regulation of TLR2 signaling by modulating PI3K (show PIK3CA Proteins) activity.

  8. in the absence of ligand the mobilities of "flap (show ALOX5AP Proteins)" and "loop" regions of IMPDH-II (1B3O) structures are mostly controlled by the four (W 1, W 2, W 3, and W 4) conserved water molecular centers and their dynamics

  9. resequenced IMPDH1 (show IMPDH1 Proteins) and IMPDH2 using DNA from 288 individuals from three ethnic groups and performed functional genomic studies of the sequence variants observed; identfied 25 SNPs, 24 novel, in IMPDH2

  10. IMPDH2 is directly involved in the development of chemoresistance in osteosarcoma cells

Mouse (Murine) IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2) interaction partners

  1. IMPDH2 mediated guanine nucleotide synthesis is essential for normal development of the enteric nervous system and other neural crest derivatives.

IMPDH2 Protein Profile

Protein Summary

This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.

Gene names and symbols associated with IMPDH2

  • IMP (inosine 5'-monophosphate) dehydrogenase 2 (IMPDH2)
  • IMP (inosine 5'-monophosphate) dehydrogenase 2 (impdh2)
  • inosine monophosphate dehydrogenase 2 (impdh2)
  • IMP (inosine 5'-monophosphate) dehydrogenase 2 (Impdh2)
  • IMP (inosine monophosphate) dehydrogenase 2 (impdh2)
  • inosine 5'-phosphate dehydrogenase 2 (impdh2)
  • inosine 5'-phosphate dehydrogenase 2 (Impdh2)
  • cb635 protein
  • imp2 protein
  • IMPD protein
  • IMPD 2 protein
  • IMPD2 protein
  • IMPDH-II protein
  • impdh2 protein
  • IMPDH 2 protein
  • wu:fb64g02 protein
  • wu:fc43f09 protein

Protein level used designations for IMPDH2

IMP (inosine monophosphate) dehydrogenase 2 , inosine monophosphate dehydrogenase 2 , IMP (inosine 5'-monophosphate) dehydrogenase 2 , hCG2002013-like , inosine-5'-monophosphate dehydrogenase 2-like , IMP oxireductase 2 , IMPD 2 , IMPDH 2 , inosine 5' phosphate dehydrogenase 2 , inosine monophosphate dehydrogenase type II , inosine-5'-monophosphate dehydrogenase 2 , IMP dehydrogenase 2 , IMPDH-II , inosine 5'-phosphate dehydrogenase 2 , inosine 5-monophosphate dehydrogenase 2 , IMP dehydrogenase type II

GENE ID SPECIES
100063255 Equus caballus
398453 Xenopus laevis
460362 Pan troglodytes
493428 Xenopus (Silurana) tropicalis
708307 Macaca mulatta
100020776 Monodelphis domestica
100196657 Salmo salar
100220774 Taeniopygia guttata
100355621 Oryctolagus cuniculus
100387794 Callithrix jacchus
100443958 Pongo abelii
100478982 Ailuropoda melanoleuca
100561879 Anolis carolinensis
3615 Homo sapiens
416058 Gallus gallus
476630 Canis lupus familiaris
511969 Bos taurus
301005 Rattus norvegicus
317745 Danio rerio
399236 Xenopus laevis
23918 Mus musculus
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