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IMP3 encodes the human homolog of the yeast Imp3 protein. Additionally we are shipping IMP3 Antibodies (75) and IMP3 Kits (1) and many more products for this protein.
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IMP3 (show IGF2BP3 Proteins) is a reliable marker for the diagnosis of colorectal cancer in endoscopic biopsies.
Overexpression of IMP3 (show IGF2BP3 Proteins) and EGFR (show EGFR Proteins) were significantly associated with shorter periods of metastasis-free and disease-free survival of malignant phyllodes tumor of the breast.
IMP-3 and its protein partners ILF3/NF90 and PTBP1 bind to the 3'UTRs of the cyclin mRNAs and protect them from the translational repression induced by miRNA-dependent recruitment of AGO2/GW182 complex in human cancer cells.
S100P (show S100P Proteins) achieved 96.4% sensitivity, 93.3% specificity, 98.2% PPV (show PPP6C Proteins), 87.5% NPV and 95.8% total accuracy, while IMP3 (show IGF2BP3 Proteins) achieved 91.2% sensitivity, 86.7% specificity, 96.2% PPV (show PPP6C Proteins), 72.2% NPV and 90.3% total accuracy for pancreatic ductal adenocarcinoma (PDA).Both markers were sensitive and specific for diagnosis of PDA.
This study aimed to demonstrate the usefulness of mRNA expression levels of IMP3 (show IGF2BP3 Proteins) in brush cytology specimens combined with cytology for the diagnosis of malignant biliary stricture
Tissue overexpression of IMP3 (show IGF2BP3 Proteins) might be used as a predictor of advanced disease or lymph node metastasis, and is associated with poorer prognosis in gastric cancers.
EGF (show EGF Proteins) stimulates IMP-3 (show IGF2BP3 Proteins) expression.
IMP3 (show IGF2BP3 Proteins) may play a certain role in hydatidiform moles progression, and it may serve as a prognostic biomarker for this disease.
Our results showed that IMP3 (show IGF2BP3 Proteins) immunostaining has a higher sensitivity and specificity than mesothelin (show MSLN Proteins) for the diagnosis of pancreatic ductal adenocarcinoma. IMP3 (show IGF2BP3 Proteins) and mesothelin (show MSLN Proteins) may be useful markers in distinguishing neoplastic from reactive lesions of the pancreas in instances where this is impossible by morphology alone in surgical pathology practice.
Our study clearly demonstrated differentiation-dependent expression of IMP3 (show IGF2BP3 Proteins) in chondrosarcoma, and suggests IMP3 (show IGF2BP3 Proteins) as a novel marker for differentiating problematic cases of enchondroma from well-differentiated chondrosarcomas
IGF2BP3 regulated transcripts via targeting elements within 3' untranslated regions (3'UTR)
Imp3 (show SPPL2A Proteins) as a key regulator of stem-like tumorigenic characteristics in osteosarcoma cells
This gene encodes the human homolog of the yeast Imp3 protein. The protein localizes to the nucleoli and interacts with the U3 snoRNP complex. The protein contains an S4 domain.
U3 small nucleolar ribonucleoprotein protein IMP3
, IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast)
, U3 snoRNP protein 3 homolog
, U3 snoRNP protein IMP3
, IGF-II mRNA-binding protein 3
, IGF2 mRNA-binding protein 3
, VICKZ family member 3
, insulin-like growth factor 2 mRNA-binding protein 3
, insulin-like growth factor 2, binding protein 3