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IQ Motif Containing GTPase Activating Protein 2 Proteins (IQGAP2)

IQGAP2 encodes a member of the IQGAP family. Additionally we are shipping IQGAP2 Antibodies (54) and IQGAP2 Kits (5) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat IQGAP2 IQGAP2 100360623  
IQGAP2 10788 Q13576
IQGAP2 544963 Q3UQ44
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Top IQGAP2 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

IQGAP2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for IQ Motif Containing GTPase Activating Protein 2 (IQGAP2) Interaction Partners

Xenopus laevis IQ Motif Containing GTPase Activating Protein 2 (IQGAP2) interaction partners

  1. Suppression of XIQGAP2 expression caused ectodermal lesions in the neurula stage embryos.

Human IQ Motif Containing GTPase Activating Protein 2 (IQGAP2) interaction partners

  1. Thus, these data identified IQGAP2 as a novel tumor suppressor for ovarian cancer to inhibit cell invasion through regulating Wnt/b-catenin signaling, and provided a new biomarker and potential therapeutic strategy for this disease.

  2. we identified IQGAP2 as a human and zebrafish podocyte gene product that is downregulated in microarray data sets from kidney biopsies of human patients with focal segmental glomerulosclerosis and minimal change nephrotic syndrome.

  3. Data show that IQ motif-containing GTPase-activating protein 2 (IQGAP2) expression is altered in colitis.

  4. IQGAP1, IQGAP2, and IQGAP3 have diverse roles in vertebrate physiology, operating in the kidney, nervous system, cardiovascular system, pancreas, and lung. (Review)

  5. Low IQGAP2 expression was associated with hepatocellular carcinoma.

  6. The first IQ-motifs from IQGAP2 and IQGAP3 form transient interactions with calmodulin (show CALM1 Proteins) in the absence of calcium.

  7. observations strongly indicate that IQGAP2 is a surveillance type of tumour suppressor for prostate cancer

  8. increased IQGAP1 and/or decreased IQGAP2 contribute to the pathogenesis of human HCC (show FAM126A Proteins).

  9. The top-ranked SNP, rs457717 for association with age-related hearing impairment(P-value 3.55 x 10(-7)), was localised in an intron of the IQ motif-containing GTPase (show RACGAP1 Proteins)-activating-like protein (IQGAP2).

  10. The gene for the putative rac1/cdc42 effector (show FNBP1L Proteins) protein IQGAP2 was found in the PAR (show JTB Proteins) gene cluster at 5q13, flanked by PAR1 (show MARK2 Proteins) & encompassing PAR3 (show F2RL2 Proteins). It functions as a GTP (show AK3 Proteins)-dependent effector protein in thrombin (show F2 Proteins)-induced platelet cytoskeletal reorganization.

Mouse (Murine) IQ Motif Containing GTPase Activating Protein 2 (IQGAP2) interaction partners

  1. Data show that complete loss of IQ motif-containing GTPase-activating protein 2 (IQGAP2) gene leads to protection from dextran sulfate sodium (DSS (show PMP22 Proteins))-induced colitis.

  2. Transcript profiling identifies iqgap2(-/-) mouse as a model for advanced human hepatocellular carcinoma.

  3. Phosphoinositide module is defined by a C-terminal 105-107 amino acid region of which IQGAP1 and -2, but not IQGAP3, binds preferentially to phosphatidylinositol 3,4,5-trisphosphate (PtdInsP(3)).

  4. murine IQGAP2 selectively regulates the facilitated phase of hepatic fatty acid uptake both in vitro and in vivo

  5. Development of hepatocellular carcinoma in Iqgap2-deficient mice is Iqgap1 dependent.

IQGAP2 Protein Profile

Protein Summary

This gene encodes a member of the IQGAP family. The protein contains three IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility.

Gene names and symbols associated with IQGAP2

  • IQ motif containing GTPase activating protein 2 (iqgap2)
  • IQ motif containing GTPase activating protein 2 (IQGAP2)
  • IQ motif containing GTPase activating protein 2 (LOC100360623)
  • IQ motif containing GTPase activating protein 2 (Iqgap2)
  • 4933417J23Rik protein
  • A630053O10 protein
  • AI788777 protein
  • IQGAP2 protein
  • XIQGAP2 protein

Protein level used designations for IQGAP2

IQ motif containing GTPase activating protein 2 , ras GTPase-activating-like protein IQGAP2-like , ras GTPase-activating-like protein IQGAP2

GENE ID SPECIES
398588 Xenopus laevis
461801 Pan troglodytes
479177 Canis lupus familiaris
100124996 Xenopus (Silurana) tropicalis
100168908 Acyrthosiphon pisum
100360623 Rattus norvegicus
100400958 Callithrix jacchus
100446817 Pongo abelii
100519536 Sus scrofa
10788 Homo sapiens
544963 Mus musculus
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