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anti-ISL LIM Homeobox 1 (ISL1) Antibodies

ISL1 encodes a member of the LIM/homeodomain family of transcription factors. Additionally we are shipping ISL LIM Homeobox 1 Proteins (8) and ISL LIM Homeobox 1 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ISL1 3670 P61371
ISL1 64444 P61374
ISL1 16392 P61372
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Top anti-ISL LIM Homeobox 1 Antibodies at antibodies-online.com

Showing 10 out of 115 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of Islet-1 / ISL1 Antibody (Center) in MDA-MB231 cell line lysates (35ug/lane). This demonstrates the ISL1 antibody detected the ISL1 protein (arrow). Western blot analysis of Islet-1 / ISL1 Antibody (Center) in mouse bladder tissue lysates (35ug/lane). This demonstrates the ISL1 antibody detected the ISL1 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated ICC, ELISA, WB Figure 1: Confocal immunofluorescence analysis of HEK293 cells trasfected with full-length ISL1-hIgGFc using ISL1 mouse mAb (green) . Blue: DRAQ5 fluorescent DNA dye. Figure 2: Western blot analysis using ISL1 mouse mAb against full-length ISL1 (aa1-349) -hIgGFc transfected HEK293 cell lysate (1) . 100 μL Log in to see 3 to 4 Days
$393.80
Details
Human Mouse Un-conjugated ICC, IHC, ELISA, WB Figure 1: Confocal immunofluorescence analysis of HEK293 cells trasfected with full-length ISL1-hIgGFc using ISL1 mouse mAb (green) . Blue: DRAQ5 fluorescent DNA dye. Figure 2: Immunohistochemical analysis of paraffin-embedded human lung cancer (left) and cervical carcinoma (right), showing nuclear localization using ISL1 mouse mAb with DAB staining. 100 μL Log in to see 3 to 4 Days
$442.20
Details
Chicken Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB WB Image SH-SY5Y whole cell and nuclear extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with Islet 1 antibody , diluted at 1:10000. IHC-P Image Islet 1 antibody detects Islet 1 protein at nucleus on rat fore brain by immunohistochemical analysis. Sample: Paraffin-embedded rat fore brain. Islet 1 antibody , dilution: 1:100. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Mouse Un-conjugated IF, ELISA, WB Immunofluorescence of monoclonal antibody to ISL1 on HeLa cell. [antibody concentration 10 ug/ml] ISL1 monoclonal antibody (M05), clone 2E7 Western Blot analysis of ISL1 expression in PC-12 . 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB ISL1 Antibody (Center)  western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the ISL1 antibody detected the ISL1 protein (arrow). ISL1 Antibody (Center)  western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the ISL1 antibody detected the ISL1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated EIA, IF, WB 0.1 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated IF, IHC (p), WB 0.1 mL Log in to see 6 to 8 Days
$434.50
Details

ISL1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-ISL LIM Homeobox 1 Antibodies

  1. Human Monoclonal ISL1 Primary Antibody for IF, ELISA - ABIN561536 : Guo, Wang, Zhang, Liu, Chen, Ma, Zhou: ISL1 promotes pancreatic islet cell proliferation. in PLoS ONE 2011 (PubMed)
    Show all 4 references for ABIN561536

  2. Human Monoclonal ISL1 Primary Antibody for EIA, IF - ABIN1107887 : Elshatory, Gan: The LIM-homeobox gene Islet-1 is required for the development of restricted forebrain cholinergic neurons. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2008 (PubMed)

  3. Human Polyclonal ISL1 Primary Antibody for EIA, WB - ABIN952960 : Genead, Danielsson, Wärdell, Kjaeldgaard, Westgren, Sundström, Franco-Cereceda, Sylvén, Grinnemo: Early first trimester human embryonic cardiac Islet-1 progenitor cells and cardiomyocytes: Immunohistochemical and electrophysiological characterization. in Stem cell research 2010 (PubMed)

More Antibodies against ISL LIM Homeobox 1 Interaction Partners

Xenopus laevis ISL LIM Homeobox 1 (ISL1) interaction partners

  1. Results describe the expression pattern of Xenopus islet-1 (Xisl-1) in the context of cardiovascular development.

  2. Knock-down of Xisl-1 by specific morpholino leads to severe developmental defects, including eye and heart failure.

Human ISL LIM Homeobox 1 (ISL1) interaction partners

  1. SSBP3 (show SSBP3 Antibodies) Interacts With Islet-1 and Ldb1 (show LDB1 Antibodies) to Impact Pancreatic beta-Cell Target Genes

  2. Concurrent ISL1/HOXA9 (show HOXA9 Antibodies) methylation in HG-NMIBC reliably predicted tumour recurrence and progression within one year (Positive Predictive Value 91.7%), and was associated with disease-specific mortality

  3. Isl1 overexpression in embryonic stem cells results in normal electrophysiologically functioning cells.

  4. The present study identified the first genome-wide significant locus for classic bladder exstrophy at chromosomal region 5q11.1, and provides strong evidence for the hypothesis that ISL1 is the responsible candidate gene in this region.

  5. Suggest that ISL-1 may be a useful prognostic biomarker and may represent a novel therapeutic target for gastric adenocarcinoma.

  6. Tcf7l2 (show TCF7L2 Antibodies) is regulating proinsulin (show INS Antibodies) expression directly via Isl1, Ins1 (show FOXM1 Antibodies) and indirectly via MafA (show KLRG1 Antibodies), NeuroD1 (show NEUROD1 Antibodies) and Pdx1 (show PDX1 Antibodies).

  7. ISL-1 is tightly linked to non-Hodgkin lymphoma proliferation and development by promoting c-Myc (show MYC Antibodies) transcription, and its aberrant expression was regulated by p-STAT3 (show STAT3 Antibodies)/p-c-Jun (show JUN Antibodies)/ISL-1 complex activation.

  8. Overexpression of ISL1 in human mesnchymal stem cells promotes angiogenesis in vitro and in vivo through increasing secretion of MCP3 and other paracrine factors.

  9. ISL1 is commonly expressed in rhabdomyosarcoma, particularly the alveolar subtype

  10. Results suggest that rs1017 ISL1 contributed to the risk of Congenital heart disease (CHD) in Chinese Han people, and the gene may be involved in the formation and development of the heart.

Mouse (Murine) ISL LIM Homeobox 1 (ISL1) interaction partners

  1. These results show that ISL1 is necessary for maximal thyrotrope response to hypothyroidism, in addition to its role in development of Rathke's pouch.

  2. the Isl1/Ldb1 (show LDB1 Antibodies) complex orchestrates a network for heart-specific transcriptional regulation and coordination in three-dimensional space during cardiogenesis.

  3. All E1 sequences from lamprey to mouse responded equally well to Phox2a (show PHOX2A Antibodies) and the Isl1-Lhx3 (show LHX3 Antibodies) complex. Conversely, E2, the enhancer for limb-innervating motor neurons, was only found in tetrapod animals

  4. Isl1 alternative splicing varies across different retinal cell types. Two isoforms of Isl1 differ functionally as transcriptional activators.

  5. this study gives new insights into transcriptional regulating mechanisms of Wnt (show WNT2 Antibodies)-mediated Isl1 expression during cardiomyocyte differentiation.

  6. results demonstrate that ISL1 regulates approximately one-third of SAN-specific genes, indicate that a combination of ISL1 and other SAN transcription factors could be utilized to generate pacemaker cells

  7. lack both Isl1 and Isl2 (show ISL2 Antibodies), large numbers of motor neurons exited the neural tube, even prior to the appearance of boundary cap cells at the ventral exit points

  8. Tcf7l2 (show TCF7L2 Antibodies) is regulating proinsulin (show INS Antibodies) expression directly via Isl1, Ins1 and indirectly via MafA (show MAFA Antibodies), NeuroD1 (show NEUROD1 Antibodies) and Pdx1 (show PDX1 Antibodies).

  9. Data indicate that LIM-homeodomain (show LHX2 Antibodies) transcription factor Islet 1 is necessary for hypothalamic proopiomelanocortin (show POMC Antibodies) gene (Pomc (show POMC Antibodies)) expression during embryogenesis.

  10. Pou4f2 (show POU4F2 Antibodies) and Isl1, are sufficient to specify the retinal ganglion cell fate in ATOH7 (show ATOH7 Antibodies) deficient mice

Zebrafish ISL LIM Homeobox 1 (ISL1) interaction partners

  1. Arx contributes to patterning in the prethalamic region, while Isl1 is required for differentiation of prethalamic dopaminergic neurons.

  2. Ajuba plays a central role in regulating the second heart field during heart development by linking retinoic acid signaling to the function of Isl1, a key transcription factor in cardiac progenitor cells.

  3. Isl1 is required for the selective outgrowth of the peripheral axons of Rohon-beard neurons.

  4. prdm1a (show PRDM1 Antibodies) Regulates sox10 (show SOX10 Antibodies) and islet1 in the development of neural crest and Rohon-Beard sensory neurons.

  5. By direct comparison of the upstream flanking regions of the zebrafish and human isl1 genes, we identified another highly conserved noncoding element.

  6. primary motoneuron subtypes are likely to be specified by factors that act in parallel to or upstream of islet1 and islet2

  7. Nkx6 proteins regulate MiP (show MIP Antibodies) motorneuron development at least in part by maintaining the islet1 expression that is required both to promote the MiP (show MIP Antibodies) subtype and to suppress interneuron development.

ISL LIM Homeobox 1 (ISL1) Antigen Profile

Protein Summary

This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young.

Gene names and symbols associated with ISL1

  • ISL LIM homeobox 1 (isl1) antibody
  • ISL LIM homeobox 1 (ISL1) antibody
  • ISL LIM homeobox 1 (Isl1) antibody
  • ISL1 transcription factor, LIM/homeodomain (Isl1) antibody
  • islet1 (isl1) antibody
  • Isl-1 antibody
  • isl-1=homeobox antibody
  • Islet-1 antibody
  • ISLET1 antibody
  • Xisl-1 antibody
  • Xislet-1 antibody

Protein level used designations for ISL1

islet-1 , ISL1 transcription factor, LIM/homeodomain, (islet-1) , domesticus (clone 1.7 kB) islet-1 , insulin gene enhancer protein ISL-1 , ISL1 transcription factor, LIM/homeodomain , ISL1 transcription factor LIM/homeodomain (islet-1) , ISL1 transcription factor, LIM/homeodomain 1 , isl-1 homeobox , Insulin gene enhancer protein ISL-1 , Islet 1 , Lim-homeodomain protein Islet1 , insulin related protein , insulin gene enhancer protein isl-1

GENE ID SPECIES
100126604 Xenopus laevis
396383 Gallus gallus
3670 Homo sapiens
614040 Bos taurus
64444 Rattus norvegicus
101836649 Mesocricetus auratus
16392 Mus musculus
30147 Danio rerio
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