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LIM homeobox transcription factor; involved in topographic organization of motor neurons. Additionally we are shipping ISL LIM Homeobox 2 Proteins (6) and ISL LIM Homeobox 2 Kits (1) and many more products for this protein.
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Human Polyclonal ISL2 Primary Antibody for EIA, WB - ABIN952961
Li, Zhang, He, Wang, Yuan, Yuan, Liao, Deng, Xiao, Zhu, Wang, Wu, Liu: Cloning and expression of a novel human gene, Isl-2, encoded a LIM-homeodomain protein. in Molecular biology reports 2007
Show all 3 references for ABIN952961
Chicken Polyclonal ISL2 Primary Antibody for WB - ABIN2780062
Svärd, Heby-Henricson, Henricson, Persson-Lek, Rozell, Lauth, Bergström, Ericson, Toftgård, Teglund: Genetic elimination of Suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway. in Developmental cell 2006
lack both Isl1 (show ISL1 Antibodies) and Isl2, large numbers of motor neurons exited the neural tube, even prior to the appearance of boundary cap cells at the ventral exit points
X-ray crystal- and small-angle x-ray scattering-derived solution structures of an Lhx4 (show LHX4 Antibodies).Isl2 complex exhibit many similarities with that of Lhx3 (show LHX3 Antibodies).Isl1 (show ISL1 Antibodies); structural differences supported by mutagenic studies reveal differences in the mechanisms of binding.
Isl2 specifies RGC laterality by repressing an ipsilateral pathfinding program unique to VTC RGCs and involving Zic2 (show ZIC2 Antibodies) and EphB1 (show EPHB1 Antibodies). This genetic hierarchy controls binocular vision
The second wave of expression at E12.5 includes Lhx3 (show LHX3 Antibodies), 5, 9, Isl2, and Lmx1b (show LMX1B Antibodies) in the differentiating sensory epithelia with cellular specificities.
Successful purification and crystallization of an engineered complex comprising the LIM (show PDLIM5 Antibodies) domains of motor neuron protein Lhx4 (show LHX4 Antibodies) and the Lim (show PDLIM5 Antibodies) binding domain of Isl2 (islet 2 protein) are reported.
Data describe how the dosage of LIM homeodomain (show LHX2 Antibodies) proteins Isl1 (show ISL1 Antibodies) and Isl2 and LIM (show PDLIM5 Antibodies)-only protein Lmo4 (show LMO4 Antibodies) influences the assembly and function of complexes involved in the generation of spinal motor neurons (MNs) and V2a interneurons (INs (show INS Antibodies)).
Experiments in Isl2/EphA3 (show EPHA3 Antibodies) knock-in mice test the interactions between effects of molecular labels and correlated activity during the development of neural connectivity.
The broad expression of Isl-2 gene in tissues during embryogenesis and adult development suggests that it may be involved in both differentiation and maintenance of these tissues and might play an important role.
Prdm14 (show PRDM14 Antibodies) regulates caudal (show CAD Antibodies) rimary axon outgrowth through activation of islet2 expression.
primary motoneuron subtypes are likely to be specified by factors that act in parallel to or upstream of islet1 (show ISL1 Antibodies) and islet2
LIM homeobox transcription factor; involved in topographic organization of motor neurons
insulin gene enhancer protein ISL-2
, islet 2
, domesticus (clone 1.6 kB) islet-2
, ISL2 transcription factor, LIM/homeodomain, (islet-2)
, insulin related protein 2 (islet 2)
, insulin gene enhancer protein isl-2
, insulin gene enhancer protein isl-2a