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Importin 4 Proteins (IPO4)

Functions in nuclear protein import as nuclear transport receptor. Additionally we are shipping Importin 4 Antibodies (18) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
IPO4 79711 Q8TEX9
IPO4 75751 Q8VI75
Rat IPO4 IPO4 290228  
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Top Importin 4 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

IPO4 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

Mouse (Murine)

More Proteins for Importin 4 (IPO4) Interaction Partners

Human Importin 4 (IPO4) interaction partners

  1. report a function of IPO4 and nuclear import in the Fanconi anemia (show PALB2 Proteins) pathway of DNA repair

  2. demonstrated that vitamin D receptor (VDR) has two nuclear import systems: ligand-dependent & ligand-independent pathways, & that importin 4 fulfills the ligand-independent nuclear transport through the interaction with the amino terminus of VDR (show CYP27B1 Proteins)

  3. importins 4 and 7 accomplish nuclear import of HIF-1alpha (show HIF1A Proteins) more efficiently than the classical importin alpha (show KPNA4 Proteins)/beta NLS (show ALDH1A2 Proteins) receptor.

Mouse (Murine) Importin 4 (IPO4) interaction partners

  1. report a function of IPO4 and nuclear import in the Fanconi anemia (show PALB2 Proteins) pathway of DNA repair

  2. Metallothionein (show MT Proteins) deficient mice have a marked decrease in Importin 4 transcripts during acute lung injury

Importin 4 (IPO4) Protein Profile

Protein Summary

Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran- dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). Mediates the nuclear import of RPS3A. In vitro, mediates the nuclear import of human cytomegalovirus UL84 by recognizing a non-classical NLS.

Gene names and symbols associated with Importin 4 Proteins (IPO4)

  • importin 4 (IPO4)
  • importin 4 (Ipo4)
  • 8430408O15Rik protein
  • AA409693 protein
  • Imp4 protein
  • Imp4a protein
  • RanBP4 protein

Protein level used designations for Importin 4 Proteins (IPO4)

importin 4 , imp4b , importin-4 , importin-4b , ran-binding protein 4 , ranBP4 , imp4 , importin 4a , importin-4a

GENE ID SPECIES
744886 Pan troglodytes
79711 Homo sapiens
75751 Mus musculus
290228 Rattus norvegicus
480260 Canis lupus familiaris
100157703 Sus scrofa
510372 Bos taurus
Selected quality suppliers for Importin 4 Proteins (IPO4)
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