Inhibitor of DNA Binding 4, Dominant Negative Helix-Loop-Helix Protein Proteins (ID4)

ID4 encodes a member of the inhibitor of DNA binding (ID) protein family. Additionally we are shipping ID4 Antibodies (79) and ID4 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ID4 15904 P41139
Rat ID4 ID4 291023  
ID4 3400 P47928
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Top ID4 Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
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HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 60 to 71 Days
$2,271.50
Details

ID4 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
, ,

More Proteins for Inhibitor of DNA Binding 4, Dominant Negative Helix-Loop-Helix Protein (ID4) Interaction Partners

Mouse (Murine) Inhibitor of DNA Binding 4, Dominant Negative Helix-Loop-Helix Protein (ID4) interaction partners

  1. results indicate that Id4 marks spermatogonial stem cells in the mouse testis.

  2. ID4 marks a stem cell-enriched subset of the mammary basal cell population. ID4 maintains the mammary stem cell pool by suppressing key factors required for luminal differentiation.

  3. Id4 regulates NKX3.1, Sox9 and PTEN.

  4. Id4 is a novel regulator of estrogen signaling, where Id4 restrains ERalpha (show ESR1 Proteins) expression in the basal and luminal cellular compartments of the mammary gland and regulates estrogen biosynthesis in the ovary

  5. High expression levels of Id1 (show ID1 Proteins)-4 proteins may play important roles in regulating retinal progenitor cell proliferation and differentiation.

  6. CpG-rich islands within the Id2 and Id4 genes were bound by PRMT5 (show PRMT5 Proteins) and were hypomethylated in PRMT5 (show PRMT5 Proteins)-deficient cells, suggesting that PRMT5 (show PRMT5 Proteins) plays a role in gene silencing during glial cell

  7. ID4 promotes mammary gland development by suppressing p38MAPK (show MAPK14 Proteins) activity.

  8. Study confirms the importance of the silencing of ID4 in murine and human CLL pathogenesis.

  9. Id4 was identified as a key transcription factors enriched in the early phase of differentiation and affecting the differentiation of both osteoblasts and adipocyte cell types.

  10. ID4 has a role in adipocyte differentiation and the implications of this regulation for adipose tissue formation

Zebrafish Inhibitor of DNA Binding 4, Dominant Negative Helix-Loop-Helix Protein (ID4) interaction partners

  1. id4 appears to control the number of endocardial cells that contribute to the AV valves by regulating Wnt (show WNT2 Proteins) signaling in the developing AVC endocardium

Human Inhibitor of DNA Binding 4, Dominant Negative Helix-Loop-Helix Protein (ID4) interaction partners

  1. A cell-autonomous positive-signaling circuit is associated with the PDGFB (show PDGFB Proteins)-NO-ID4-regulatory axis in glioblastoma cells.

  2. ID4 expression induces AR expression in PC3 (show PCSK1 Proteins) cells, which generally lack AR. ID4 expression increased apoptosis and decreased cell proliferation and invasion.

  3. CEACAM1 (show CEACAM1 Proteins) is able to maintain the active transcription of ID4 by an epigenetic mechanism involving HDAC4 (show HDAC4 Proteins) and CaMK2D (show CAMK2D Proteins), and the same kinase enables lumen formation by CEACAM1 (show CEACAM1 Proteins)

  4. In the PPI network, genes may be involved in Down syndrome (DS) by interacting with others, including nuclear receptor subfamily 4 group A member 2 (NR4A2 (show NR4A2 Proteins))early growth response (EGR)2 (show EGR2 Proteins) and NR4A2EGR3. Therefore, RUNX1 (show RUNX1 Proteins), NR4A2 (show NR4A2 Proteins), EGR2 (show EGR2 Proteins), EGR3 (show EGR3 Proteins) and ID4 may be key genes associated with the pathogenesis of DS.

  5. changes in gene amplification in the mitochondrial genome and in the ID4 gene promoter methylation region in patients with chronic aplastic anemia (CAA) suffering from Kidney (Shen) yin deficiency or Kidney yang deficiency, were analyzed.

  6. Hypermethylation of ID4 promotes the proliferation of Burkitt's lymphoma cells; ID4 may function as a tumor suppressor and can be targeted with demethylating compounds such as CdR (show RUNX1T1 Proteins) for the treatment of Burkitt's lymphoma

  7. the unmethylation of ID4 is an epigenetic predictor of BRCAness phenotype in breast tumors.

  8. ID4 hypomethylation is present in tamoxifen-resistant breast cancer, and it may serve as a potential biomarker in distinguishing tamoxifen-resistant breast cancer.

  9. ID4 marks a stem cell-enriched subset of the mammary basal cell population. ID4 is specifically expressed by a subset of human basal-like breast cancer that possess a very poor prognosis and a transcriptional signature similar to a mammary stem cell.

  10. The results showed that the detection of ID4 methylation positivity rates and levels could be a useful biomarker for MDS (show PAFAH1B1 Proteins) diagnosis.

ID4 Protein Profile

Protein Summary

This gene encodes a member of the inhibitor of DNA binding (ID) protein family. These proteins are basic helix-loop-helix transcription factors which can act as tumor suppressors but lack DNA binding activity. Consequently, the activity of the encoded protein depends on the protein binding partner.

Gene names and symbols associated with ID4

  • inhibitor of DNA binding 4 (Id4)
  • inhibitor of DNA binding 4 (id4)
  • inhibitor of DNA binding 4, dominant negative helix-loop-helix protein (id4-a)
  • inhibitor of DNA binding 4, dominant negative helix-loop-helix protein (ID4)
  • bhlhb27 protein
  • cb547 protein
  • fb77d04 protein
  • id4 protein
  • id4a protein
  • IDB4 protein
  • sb:cb547 protein
  • wu:fb77d04 protein
  • zgc:123214 protein

Protein level used designations for ID4

DNA-binding protein inhibitor ID-4 , inhibitor of DNA binding 4 a , class B basic helix-loop-helix protein 27

GENE ID SPECIES
15904 Mus musculus
291023 Rattus norvegicus
664761 Danio rerio
380396 Xenopus laevis
374150 Gallus gallus
3400 Homo sapiens
610666 Canis lupus familiaris
100144508 Sus scrofa
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