You are viewing an incomplete version of our website. Please click to reload the website as full version.

Inositol Hexakisphosphate Kinase 2 Proteins (IP6K2)

IP6K2 encodes a protein that belongs to the inositol phosphokinase (IPK) family. Additionally we are shipping IP6K2 Antibodies (39) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
IP6K2 51447 Q9UHH9
IP6K2 59268 Q9R0U1
IP6K2 76500 Q80V72
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top IP6K2 Proteins at antibodies-online.com

Showing 7 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,184.50
Details
Yeast Rabbit His tag   1 mg Log in to see 56 to 66 Days
$3,184.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 9 to 11 Days
$229.85
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

IP6K2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Rat (Rattus)

Mouse (Murine)

Top referenced IP6K2 Proteins

  1. Human IP6K2 Protein expressed in Wheat germ - ABIN1308004 : Ardi, Alexander, Johnson, McAlpine: Macrocycles that inhibit the binding between heat shock protein 90 and TPR-containing proteins. in ACS chemical biology 2011 (PubMed)

More Proteins for Inositol Hexakisphosphate Kinase 2 (IP6K2) Interaction Partners

Zebrafish Inositol Hexakisphosphate Kinase 2 (IP6K2) interaction partners

  1. IP6K2 is a positive regulator of Hh signaling.

Human Inositol Hexakisphosphate Kinase 2 (IP6K2) interaction partners

  1. An alpha-helical pair and a rare, two-turn 310 helix, that together form a substrate-binding pocket of IP6K2.

  2. FGF2 (show FGF2 Proteins)-signaling involves the inositol polyphosphate cascade, including inositol hexakisphosphate kinase (IP6K), and demonstrate that IP6K1,2 regulates Runx2 (show RUNX2 Proteins) and osteoblast gene expression.

  3. Genetic polymorphisms in IP6K2 gene is associated with autoimmune disease.

  4. Casein kinase-2 mediates cell survival through phosphorylation and degradation of inositol hexakisphosphate kinase-2.

  5. Gene disruption of IP6K2 in colorectal cancer cells selectively impairs p53 (show TP53 Proteins)-mediated apoptosis, instead favoring cell-cycle arrest. IP6K2 acts by binding directly to p53 (show TP53 Proteins) and decreasing expression of proarrest gene targets

  6. IHPK2 over expression enhances sensitivity of ovarian carcinoma cells to radiation, IFN-beta (show IFNB1 Proteins), caspase 8 (show CASP8 Proteins) and DR4 (show HLADRB4 Proteins)

  7. IHPK2-TRAF2 (show TRAF2 Proteins) binding leads to attenuation of TAK1 (show MAP3K7 Proteins)- and NF-kappaB (show NFKB1 Proteins)-mediated signaling and is partially responsible for the apoptotic activity of IHPK2.

Rabbit Inositol Hexakisphosphate Kinase 2 (IP6K2) interaction partners

  1. A role for PI3 kinase (show PIK3CA Proteins) pathway in the airway smooth muscle cellular response to insulin (show INS Proteins).

Mouse (Murine) Inositol Hexakisphosphate Kinase 2 (IP6K2) interaction partners

  1. IP6K2 is a major mediator of cancer cell migration and tumor metastasis, acting by enhancing cell-matrix adhesion and decreasing cell-cell adhesion.

  2. FGF2 (show FGF2 Proteins)-signaling involves the inositol polyphosphate cascade, including inositol hexakisphosphate kinase (IP6K), and demonstrate that IP6K1,2 regulates Runx2 (show RUNX2 Proteins) and osteoblast gene expression.

  3. Gene deletion of inositol hexakisphosphate kinase 2 predisposes to aerodigestive tract carcinoma.

IP6K2 Protein Profile

Protein Summary

This gene encodes a protein that belongs to the inositol phosphokinase (IPK) family. This protein is likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4 and affect the growth suppressive and apoptotic activities of interferon-beta in some ovarian cancers. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene names and symbols associated with IP6K2

  • inositol hexakisphosphate kinase 2 (IP6K2)
  • Inositol hexakisphosphate kinase 2 (ip6k2)
  • inositol hexaphosphate kinase 2 (ip6k2)
  • inositol hexaphosphate kinase 2 (ip6k2-b)
  • zgc:92046 (zgc:92046)
  • inositol hexaphosphate kinase 2 (ip6k2-a)
  • inositol hexaphosphate kinase 2 (MCYG_02913)
  • inositol hexaphosphate kinase 2 (LOC100227893)
  • inositol hexakisphosphate kinase 2 (Ip6k2)
  • inositol hexaphosphate kinase 2 (Ip6k2)
  • 1500005N04Rik protein
  • AW050208 protein
  • cb1087 protein
  • Ihpk2 protein
  • ihpk2a protein
  • ihpk2b protein
  • ip6k2 protein
  • MGC69075 protein
  • MGC84167 protein
  • Pius protein
  • wu:fb47g07 protein
  • wu:fi24d03 protein

Protein level used designations for IP6K2

inositol hexaphosphate kinase 2 , Inositol hexakisphosphate kinase 2 , inositol hexakisphosphate kinase 2 , inositol hexakisphosphate kinase 2-like , inositol hexaphosphate kinase 2b , inositol hexaphosphate kinase 2 a , ATP:1D-myo-inositol-hexakisphosphate phosphotransferase , insp6 kinase 2 , pi uptake stimulator , InsP6 kinase 2 , P(i)-uptake stimulator , PiUS , insP6 kinase 2 , p(i)-uptake stimulator , piUS

GENE ID SPECIES
416010 Gallus gallus
508236 Bos taurus
612831 Canis lupus familiaris
100195403 Salmo salar
100450315 Pongo abelii
100548969 Meleagris gallopavo
100594303 Nomascus leucogenys
322041 Danio rerio
379567 Xenopus laevis
436662 Danio rerio
444642 Xenopus laevis
548709 Xenopus (Silurana) tropicalis
9224853 Arthroderma otae CBS 113480
100227893 Taeniopygia guttata
51447 Homo sapiens
59268 Rattus norvegicus
100009233 Oryctolagus cuniculus
76500 Mus musculus
Selected quality suppliers for IP6K2 Proteins (IP6K2)
Did you look for something else?