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Inositol Polyphosphate Multikinase Proteins (IPMK)

IPMK encodes a member of the inositol phosphokinase family. Additionally we are shipping IPMK Antibodies (58) and IPMK Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
IPMK 253430 Q8NFU5
IPMK 69718 Q7TT16
IPMK 171458 Q99NI4
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Top IPMK Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,091.00
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

IPMK Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for Inositol Polyphosphate Multikinase (IPMK) Interaction Partners

Human Inositol Polyphosphate Multikinase (IPMK) interaction partners

  1. a severe loss of IPMK in the striatum of Huntington disease (show HTT Proteins) patients and in several cellular and animal models of the disease, is reported.

  2. A hereditary form of small intestinal carcinoid associated with a germline mutation in IPMK.

  3. Future research should focus on the hitherto unknown non-conventional import of IPMK and the potential impact of its dysregulation on IPMK signaling pathways regulating cellular growth and proliferation.

  4. Knockdown of expression and/or inhibition of function of phospholipase Cgamma1, inositol polyphosphate multikinase, which generates inositol 1,3,4,5-tetrakisphosphate (InsP) and InsP, and inositol hexakisphosphate kinase 1 (show IP6K1 Proteins)/2

  5. Our findings implicate IPMK in a transcript-selective mRNA export pathway controlled by phosphoinositide turnover that preserves genome integrity in humans.

  6. Results suggest that inositol polyphosphate multikinase (IPMK) acts as a transcriptional coactivator for p53 (show TP53 Proteins) and that it is an integral part of the p53 (show TP53 Proteins) transcriptional complex facilitating cell death.

  7. overview of possible roles of IPMK in regulation of metabolism: IPMK appears to mediate activation of mammalian target of rapamycin (mTOR (show FRAP1 Proteins)) in response to essential amino acids. IPMK appears to mediate hypothalamic control of food intake. [REVIEW]

  8. Data show that inositol polyphosphate multikinase (IPMK) interacts with the nuclear receptor steroidogenic factor 1 (SF-1 (show NR5A1 Proteins)) and phosphorylates its bound ligand Phosphatidylinositol 4,5-bisphosphate (PIP (show PIP Proteins)).

  9. Phosphorylation of S284 by protein kinase CK2 (show CSNK2A1 Proteins) significantly decreases nuclear targeting of IPMK in HEK (show EPHA3 Proteins)-293 cells.

  10. cloning of a full-length 1248-bp cDNA encoding a human inositol phosphate multikinase (IPMK); localized predominantly in the nucleus when transiently expressed in mammalian cells

Mouse (Murine) Inositol Polyphosphate Multikinase (IPMK) interaction partners

  1. a severe loss of IPMK in the striatum of Huntington disease (show HTT Proteins) patients and in several cellular and animal models of the disease, is reported.

  2. metformin-mediated activation of AMP (show TMPRSS5 Proteins)-Activated Protein Kinases was impaired in the absence of IPMK.

  3. Inositol polyphosphate multikinase is a coactivator for serum response factor-dependent induction of immediate early (show JUN Proteins) genes.

  4. Knockdown of expression and/or inhibition of function of phospholipase Cgamma1, inositol polyphosphate multikinase, which generates inositol 1,3,4,5-tetrakisphosphate (InsP) and InsP, and inositol hexakisphosphate kinase 1 (show IP6K1 Proteins)/2

  5. Inositol polyphosphate multikinase is a transcriptional coactivator required for immediate early (show JUN Proteins) gene induction.

  6. IPMK regulates glucose signaling to AMPK (show PRKAA1 Proteins) in a pathway whereby glucose activates phosphorylation of IPMK at tyrosine 174 enabling the enzyme to bind to AMPK (show PRKAA1 Proteins) and regulate its activation.

  7. Data show that in MEFs lacking IPMK, synthesis of IP5 and IP7 is abolished, but IP6 (show GPRIN2 Proteins) formation is reduced about 90%.

  8. Inositol polyphosphate multikinase (Ipk2) plays a major role in the synthesis of inositol polyphosphate messengers derived from inositol 1,4,5-trisphosphate in embryogenesis and normal development.

IPMK Protein Profile

Protein Summary

This gene encodes a member of the inositol phosphokinase family. The encoded protein has 3-kinase, 5-kinase and 6-kinase activities on phosphorylated inositol substrates. The encoded protein plays an important role in the biosynthesis of inositol 1,3,4,5,6-pentakisphosphate, and has a preferred 5-kinase activity. This gene may play a role in nuclear mRNA export. Pseudogenes of this gene are located on the long arm of chromosome 13 and the short arm of chromosome 19.

Gene names and symbols associated with IPMK

  • inositol polyphosphate multikinase (ipmk)
  • inositol polyphosphate multikinase (IPMK)
  • inositol polyphosphate multikinase b (ipmkb)
  • inositol polyphosphate multikinase (EDI_171250)
  • inositol polyphosphate multikinase (CC1G_06147)
  • inositol polyphosphate multikinase (CpipJ_CPIJ006477)
  • inositol polyphosphate multikinase (CpipJ_CPIJ016779)
  • inositol polyphosphate multikinase (PAAG_02384)
  • inositol polyphosphate multikinase (MCYG_03683)
  • inositol polyphosphate multikinase a (ipmka)
  • inositol polyphosphate multikinase (EDI_070480)
  • inositol polyphosphate multikinase (VDBG_01275)
  • inositol polyphosphate multikinase (MGYG_03269)
  • inositol polyphosphate multikinase (Tsp_05937)
  • inositol polyphosphate multikinase (Ipmk)
  • 2410017C19Rik protein
  • AA408208 protein
  • Impk protein
  • Ipk2 protein
  • ipmk protein
  • MGC83832 protein
  • si:dkey-223l5.1 protein
  • zgc:158331 protein

Protein level used designations for IPMK

inositol polyphosphate multikinase , ipk2 , inositol 1,3,4,6-tetrakisphosphate 5-kinase , inositol polyphosphate kinase 2

GENE ID SPECIES
447535 Xenopus laevis
450471 Pan troglodytes
769967 Gallus gallus
790916 Danio rerio
5881982 Entamoeba dispar SAW760
6016580 Coprinopsis cinerea okayama7130
6038564 Culex quinquefasciatus
6051256 Culex quinquefasciatus
9099041 Paracoccidioides sp. 'lutzii' Pb01
9229501 Arthroderma otae CBS 113480
100151036 Danio rerio
5884397 Entamoeba dispar SAW760
9534178 Verticillium alfalfae VaMs.102
10031058 Arthroderma gypseum CBS 118893
10911085 Trichinella spiralis
253430 Homo sapiens
69718 Mus musculus
171458 Rattus norvegicus
615135 Bos taurus
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