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Inositol Polyphosphate-5-Phosphatase K Proteins (INPP5K)

INPP5K encodes a protein with 5-phosphatase activity toward polyphosphate inositol. Additionally we are shipping INPP5K Antibodies (26) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat INPP5K INPP5K 287533  
INPP5K 19062 Q8C5L6
INPP5K 51763 Q9BT40
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Top INPP5K Proteins at antibodies-online.com

Showing 4 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

INPP5K Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,

More Proteins for Inositol Polyphosphate-5-Phosphatase K (INPP5K) Interaction Partners

Mouse (Murine) Inositol Polyphosphate-5-Phosphatase K (INPP5K) interaction partners

  1. the physiological role of Pak1 (show PAK1 Proteins)-SKIP binding is in the regulation of insulin (show INS Proteins) signaling in skeletal muscle

  2. SKIP controls the IGF-II-PI 3 (show PI3 Proteins)-kinase-Akt (show AKT1 Proteins)-mTOR (show FRAP1 Proteins) auto-regulation loop during myogenesis.

  3. Specific suppression of insulin (show INS Proteins) signaling is achieved via the spatiotemporal regulation of SKIP through the scaffolding function of Pak1 (show PAK1 Proteins).

  4. Regulation of insulin signaling and glucose transporter 4 (GLUT4) exocytosis by phosphatidylinositol 3,4,5-trisphosphate (PIP3) phosphatase, skeletal muscle, and kidney enriched inositol polyphosphate phosphatase (SKIP).

  5. Results indicate that Inpp5k 5-phosphatase is important for the control of the arginine vasopressin (show AVP Proteins)/aquaporin-2 (show AQP2 Proteins) signalling pathway and water transport in kidney collecting ducts.

  6. Silencer of death domains (SODD (show BAG4 Proteins)) inhibits skeletal muscle and kidney enriched inositol 5-phosphatase (SKIP) and regulates phosphoinositide 3-kinase (PI3K)/Akt (show AKT1 Proteins) signaling to the actin cytoskeleton.

  7. Data shoe that the N-terminal domain of SifA is sufficient to interact with the pleckstrin (show PLEK Proteins) homology domain of SKIP, forming a 1:1 complex with a micromolar dissociation constant.

  8. These results imply that SKIP regulates insulin (show INS Proteins) signaling in skeletal muscle.

  9. results suggest that SKIP (skeletal muscle and kidney-enriched inositol phosphatase) plays a negative regulatory role in Akt (show AKT1 Proteins)/ GSK-3beta/GS (glycogen synthase) pathway leading to glycogen (show GYS1 Proteins) synthesis in myocytes

Human Inositol Polyphosphate-5-Phosphatase K (INPP5K) interaction partners

  1. SKIP controls the IGF-II-PI 3 (show PI3 Proteins)-kinase-Akt (show AKT1 Proteins)-mTOR (show FRAP1 Proteins) auto-regulation loop during myogenesis.

  2. Specific suppression of insulin (show INS Proteins) signaling is achieved via the spatiotemporal regulation of SKIP through the scaffolding function of Pak1 (show PAK1 Proteins).

  3. The authors report that HBV core protein interacts with a cellular SKIP (skeletal muscle and kidney enriched inositol phosphatase) protein, an endoplasmic reticulum-located phosphoinositide 5-phosphatase (show INPP5B Proteins), both in vivo and in vitro.

INPP5K Protein Profile

Protein Summary

This gene encodes a protein with 5-phosphatase activity toward polyphosphate inositol. The protein localizes to the cytosol in regions lacking actin stress fibers. It is thought that this protein may negatively regulate the actin cytoskeleton. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene names and symbols associated with INPP5K

  • inositol polyphosphate-5-phosphatase K (Inpp5k)
  • inositol polyphosphate-5-phosphatase K (INPP5K)
  • inositol polyphosphate 5-phosphatase K (Inpp5k)
  • C62 protein
  • PPS protein
  • SKIP protein

Protein level used designations for INPP5K

C62 , inositol polyphosphate 5-phosphatase K , putative phosphoinositide 5-phosphatase type II , putative phosphoinositide 5-phosphatase type II; C62 , skeletal muscle and kidney enriched inositol phosphatase , PI-5-phosphatase related , putative PI-5-phosphatase , skeletal muscle and kidney enriched inositol polyphosphate phosphatase , skeletal muscle and kidney-enriched inositol phosphatase

GENE ID SPECIES
287533 Rattus norvegicus
454410 Pan troglodytes
514123 Bos taurus
19062 Mus musculus
51763 Homo sapiens
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