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Inositol-Trisphosphate 3-Kinase A Proteins (ITPKA)

Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. Additionally we are shipping ITPKA Antibodies (50) and ITPKA Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ITPKA 228550 Q8R071
ITPKA 3706 P23677
ITPKA 81677 P17105
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Top ITPKA Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,290.83
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

ITPKA Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,

Rat (Rattus)

More Proteins for Inositol-Trisphosphate 3-Kinase A (ITPKA) Interaction Partners

Mouse (Murine) Inositol-Trisphosphate 3-Kinase A (ITPKA) interaction partners

  1. At synapses of Inositol-1,4,5-trisphosphate 3-kinase-A deficient neurons the levels of Ins (show INS Proteins)(1,4,5)P3-5-phosphatase (inpp5a (show INPP5A Proteins)) and sarcoplasmic/endoplasmic reticulum calcium ATPase pump-2b (serca2b (show ATP2A2 Proteins)) were increased.

  2. Inositol 1,4,5-trisphosphate 3-kinase-A is a new cell motility-promoting protein that increases the metastatic potential of tumor cells by two functional activities.

  3. These data show that the absence of expression of the three isoenzymes of Itpk does not prevent the formation of IP5 and IP6 (show GPRIN2 Proteins), at least in mouse embryonic fibroblasts.[Itpka, Itpkb (show ITPKB Proteins), Itpkc (show ITPKC Proteins)]

  4. Inositol 1,4,5-trisphosphate 3-kinase A is critical for spatial and temporal regulation of spine actin remodeling, synaptic plasticity, and learning and memory via an activity-dependent Rac (show AKT1 Proteins) scaffolding mechanism.

Human Inositol-Trisphosphate 3-Kinase A (ITPKA) interaction partners

  1. Our data indicated that ITPKA expression was significantly up-regulated in hepatocellular carcinoma and could serve as a potential novel prognostic biomarker

  2. describe the crystal structure of the complex between human Ca2 (show CA2 Proteins)+/CaM (show CALM1 Proteins) and the CaM (show CALM1 Proteins)-binding region of human IP3-3K isoform A (residues 158-183)

  3. we conclude that the observed expression of ITPKA early in tumor development increases the metastatic potential of lung adenocarcinoma cells.

  4. Inositol 1,4,5-trisphosphate 3-kinase-A is a new cell motility-promoting protein that increases the metastatic potential of tumor cells by two functional activities.

  5. results highlight the potential role of the three isoforms of InsP3 3-kinase as direct InsP3 metabolizing enzymes and direct regulators of Ca2 (show CA2 Proteins)+ responses to extracellular signals

  6. We report the structure of an IPK, the human Ins (show INS Proteins)(1,4,5)P3 3-kinase-A, both free and in complexes with substrates and products.

  7. Data suggest that ITPKA may be related to carcinogenesis by the modulation of inositol polyphosphates and Ca2+ homeostasis and that ITPKA may be a potential novel molecular target and biomarker.

  8. the morphological changes induced by IP3K-A are mediated by non-enzymatic activities of the protein.

ITPKA Protein Profile

Protein Summary

Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro.

Gene names and symbols associated with ITPKA

  • inositol-trisphosphate 3-kinase A-like (LOC564528)
  • Inositol-trisphosphate 3-kinase A (ip3ka)
  • 1D-myo-inositol-trisphosphate 3-kinase A (LOC100343586)
  • inositol 1,4,5-trisphosphate 3-kinase A (Itpka)
  • inositol-trisphosphate 3-kinase A (ITPKA)
  • inositol-trisphosphate 3-kinase A (Itpka)
  • IP3-3KA protein
  • IP3KA protein

Protein level used designations for ITPKA

1D-myo-inositol-trisphosphate 3-kinase A , Inositol-trisphosphate 3-kinase A , IP3 3-kinase A , IP3-kinase A , IP3K A , inositol-trisphosphate 3-kinase A , insP 3-kinase A , inositol 1,4,5-trisphosphate 3-kinase A , inositol 1,4,5-triphosphate 3-kinase , inositol 145-triphosphate 3-kinase

GENE ID SPECIES
564528 Danio rerio
100196437 Salmo salar
100343586 Oryctolagus cuniculus
228550 Mus musculus
3706 Homo sapiens
81677 Rattus norvegicus
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