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IGF2BP1 encodes a member of the insulin-like growth factor 2 mRNA-binding protein family. Additionally we are shipping IGF2BP1 Antibodies (64) and IGF2BP1 Kits (1) and many more products for this protein.
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Human IGF2BP1 Protein expressed in Wheat germ - ABIN1307552
Hellbach, Weise, Vezzali, Wahane, Heidrich, Roidl, Pruszak, Esser, Vogel: Neural deletion of Tgfbr2 impairs angiogenesis through an altered secretome. in Human molecular genetics 2014
Our studies provide insights into a molecular mechanism that the positive function of IMP1 (show IMPA1 Proteins) to inhibit breast tumor growth and metastasis
The regions encoding 71 microRNAs (miRs) were deleted in at least 25% of tumor specimens. Five of these recurrently deleted miRs targeted the insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) gene product, and a correlating 100-fold upregulation of IGF2BP1 mRNA was seen in tumor specimens
Insight into molecular interactions between CRD-BP and MITF (show MITF Proteins) mRNA.
IGF2BP1 indirectly potentiates ETV6 (show ETV6 Proteins)/RUNX1 (show RUNX1 Proteins)-RAC1-STAT3 (show STAT3 Proteins) signaling axis by sustaining appropriate ETV6 (show ETV6 Proteins)/RUNX1 (show RUNX1 Proteins) and STAT3 (show STAT3 Proteins) transcript levels in REH (show CES1 Proteins) cells.
The findings indicate that the tumor-suppressive roles of the let-7 family are antagonized by a potent and self-promoting triangle consisting of IGF2BP1 (potentially all IGF2BPs), LIN28B and HMGA2.
The results from this study demonstrate the potential importance of the two-stem-loop motif as a target region for the inhibition of the CRD-BP-GLI1 (show GLI1 Proteins) RNA interaction and Hedgehog (show SHH Proteins) signaling pathway.
these findings suggest that miR (show MLXIP Proteins)-150 functions as a tumor suppressor in Osteosarcoma (OS) partially by targeting IGF2BP1
ETV6 (show ETV6 Proteins)/RUNX1 (show RUNX1 Proteins) transcript is a target of RNA-binding protein (show PTBP1 Proteins) IGF2BP1 in t(12;21)(p13;q22)-positive acute lymphoblastic leukemia.
Data show that ONECUT2, IGF2BP1, and ANXA2 (show ANXA2 Proteins) proteins were confirmed to be microRNA-9 (miR (show MLXIP Proteins)-9) targets and aberrantly upregulated in hepatocellular carcinoma (HCC (show FAM126A Proteins)).
The tumor-suppressive role of stromal IMP1 (show IMPA1 Proteins) and its ability to modulate protumorigenic factors suggest that IMP1 (show IMPA1 Proteins) status is important for the initiation and growth of epithelial tumors
This study showed that Zipcode binding protein 1 (ZBP1) is an mRNA-binding protein that regulates the local translation of proteins, including actin, in the growth cone and is required for Shh (show SHH Proteins)-mediated axon guidance.
High CRD-BP expression is associated with Breast Tumor.
Results identify IGF2BP1 (show B4GALNT2 Proteins) as a critical translational regulator of cIAP1 (show BIRC2 Proteins)-mediated apoptotic resistance in rhabdomyosarcoma.
This study demonstrate that ZBP1 (show ZBP1 Proteins) and the phosphorylation of ZBP1 (show ZBP1 Proteins) are required for attractive guidance of cortical neurons, and appropriate filopodial dynamics.
IMP1 (show IMPA1 Proteins) plays a role in regulating the packaging of MLV genomic RNA and can be used for improving production of retroviral vectors
WAP (show Wap Proteins)-CRD-BP mice are a novel model for mammary neoplasia and might provide insights into human breast cancer biology.
IMP-1 (show IMPA1 Proteins) associates with HuD (show ELAVL4 Proteins) and G3BP-1 (show G3BP1 Proteins) proteins in an RNA-dependent manner and binds directly to tau mRNA. We also show an RNA-dependent association between G3BP-1 (show G3BP1 Proteins) and HuD (show ELAVL4 Proteins) proteins
Two KH domains of CRD-BP are required for efficient binding to oncogenic mRNAs and for granule formation in zebrafish embryos.
This gene encodes a member of the insulin-like growth factor 2 mRNA-binding protein family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the mRNAs of certain genes, including insulin-like growth factor 2, beta-actin and beta-transducin repeat-containing protein, and regulating their translation. Two transcript variants encoding different isoforms have been found for this gene.
insulin-like growth factor 2 mRNA binding protein 1
, IGF-II mRNA-binding protein 1
, IGF2 mRNA-binding protein 1
, VICKZ family member 1
, insulin-like growth factor 2 mRNA-binding protein 1
, zip code-binding protein 1
, zipcode-binding protein 1
, coding region determinant-binding protein
, coding region determinant binding protein
, insulin-like growth factor 2, binding protein 1
, zipcode binding protein 1
, B-actin zipcode-binding protein 1
, insulin-like growth factor 2 binding protein 1
, zipcode-binding protein-1