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Insulin-Like Growth Factor 2 MRNA Binding Protein 3 Proteins (IGF2BP3)

The protein encoded by IGF2BP3 is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. Additionally we are shipping Insulin-Like Growth Factor 2 MRNA Binding Protein 3 Antibodies (61) and Insulin-Like Growth Factor 2 MRNA Binding Protein 3 Kits (14) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
IGF2BP3 10643 O00425
IGF2BP3 140488 Q9CPN8
Rat IGF2BP3 IGF2BP3 312320  
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Top Insulin-Like Growth Factor 2 MRNA Binding Protein 3 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details

IGF2BP3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Insulin-Like Growth Factor 2 MRNA Binding Protein 3 (IGF2BP3) Interaction Partners

Human Insulin-Like Growth Factor 2 MRNA Binding Protein 3 (IGF2BP3) interaction partners

  1. MicroRNA-129-1 acts as tumour suppressor and induces cell cycle arrest of GBM cancer cells through targeting IGF2BP3 and MAPK1 (show MAPK3 Proteins)

  2. IGF2BP3 regulated transcripts via targeting elements within 3' untranslated regions (3'UTR)

  3. An isocorydine derivative (d-ICD (show GNPTAB Proteins)) inhibits drug resistance by downregulating IGF2BP3 expression in hepatocellular carcinoma.

  4. Data show that insulin-like growth factor-2 (show IGF2 Proteins)-mRNA-binding proteins IGF2BP1 (show IGF2BP1 Proteins), IGF2BP2 (show IGF2BP2 Proteins), and IGF2BP3 are direct targets of microRNA-1275 (miR (show MLXIP Proteins)-1275).

  5. Our results provide insight into the link between regulation of KIF20A (show KIF20A Proteins)-mediated trafficking of IGF2BP3-containing stress granules and modulation of the motility and invasiveness in pancreatic cancers.

  6. IGF2BP3 and IGF2BP3-bound transcripts are localized in cytoplasmic RNA granules that accumulate in membrane protrusions of pancreatic cancer cells.

  7. these findings suggest that IMP3 expression may be a prognostic indicator of squamous cell carcinoma.

  8. IGF2BP3 was highly expressed in placental villi during early pregnancy, especially in cytotrophoblast cells and trophoblast column.

  9. Data show that TTK protein kinase, lymphocyte antigen 6 complex locus K (show Ly6k Proteins) and insulin (show INS Proteins)-like growth factor (IGF)-II mRNA binding protein 3 are tumor-associated antigens recognized by cytotoxic T lymphocytes and HLA-A24 (show CD164 Proteins)-restricted epitope peptides.

  10. Our results suggest that IMP3 may be an ancillary tool in identifying aggressive abdominal mesenchymal tumors other than gastrointestinal stromal tumor.

Mouse (Murine) Insulin-Like Growth Factor 2 MRNA Binding Protein 3 (IGF2BP3) interaction partners

  1. IGF2BP3 regulated transcripts via targeting elements within 3' untranslated regions (3'UTR)

Insulin-Like Growth Factor 2 MRNA Binding Protein 3 (IGF2BP3) Protein Profile

Protein Summary

The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes.

Gene names and symbols associated with IGF2BP3

  • insulin-like growth factor 2 mRNA binding protein 3 (IGF2BP3)
  • insulin-like growth factor 2 mRNA binding protein 3 (igf2bp3)
  • insulin-like growth factor 2 mRNA binding protein 3 (LOC100231176)
  • insulin-like growth factor 2 mRNA binding protein 3 (Igf2bp3)
  • 2610101N11Rik protein
  • AA522010 protein
  • Ab2-255 protein
  • AL022933 protein
  • AU045931 protein
  • CT98 protein
  • dvr1rbp protein
  • IMP-3 protein
  • IMP3 protein
  • KOC1 protein
  • Koc13 protein
  • mimp3 protein
  • Neilsen protein
  • RGD1306512 protein
  • vera protein
  • vg1rbp protein
  • VICKZ3 protein
  • wu:fb79c12 protein
  • wu:fe06h09 protein
  • zVg1RBP protein

Protein level used designations for IGF2BP3

insulin-like growth factor 2 mRNA-binding protein 3 , insulin-like growth factor 2 mRNA binding protein 3 , insulin-like growth factor 2 mRNA-binding protein 3-like , IGF II mRNA binding protein 3 , IGF-II mRNA-binding protein 3 , IGF2 mRNA-binding protein 3 , KH domain containing protein overexpressed in cancer , KH domain-containing protein overexpressed in cancer , VICKZ family member 3 , cancer/testis antigen 98 , hKOC , insulin-like growth factor 2, binding protein 3 , mIMP-3 , IMP-3 , Vg1 RBP , decapentaplegic and Vg-related 1 RNA-binding protein , decapentaplegic and Vg-related 1, RNA binding protein , vg1 RNA-binding protein , vg1-RBP

GENE ID SPECIES
539650 Bos taurus
549893 Xenopus (Silurana) tropicalis
704774 Macaca mulatta
744246 Pan troglodytes
100231176 Taeniopygia guttata
100394155 Callithrix jacchus
100602302 Nomascus leucogenys
10643 Homo sapiens
482357 Canis lupus familiaris
140488 Mus musculus
312320 Rattus norvegicus
420617 Gallus gallus
30967 Danio rerio
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