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anti-Insulin-Like Growth Factor Binding Protein, Acid Labile Subunit (IGFALS) Antibodies

The protein encoded by IGFALS is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Additionally we are shipping Insulin-Like Growth Factor Binding Protein, Acid Labile Subunit Kits (12) and Insulin-Like Growth Factor Binding Protein, Acid Labile Subunit Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
IGFALS 3483 P35858
IGFALS 16005 P70389
IGFALS 79438 P35859
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Top anti-Insulin-Like Growth Factor Binding Protein, Acid Labile Subunit Antibodies at antibodies-online.com

Showing 10 out of 42 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of IGFALS Antibody (Center) (ABIN391690) in mous... Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted wit... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 2 to 3 Days
$275.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IHC (p), WB Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$676.50
Details
Human Rabbit Un-conjugated WB IGFALS antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Goat Un-conjugated ELISA   100 μg Log in to see 8 to 10 Days
$419.83
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 8 to 10 Days
$522.50
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

IGFALS Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,
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Mouse (Murine) , , , ,

Rat (Rattus) , , ,

Top referenced anti-Insulin-Like Growth Factor Binding Protein, Acid Labile Subunit Antibodies

  1. Human Polyclonal IGFALS Primary Antibody for ELISA, WB - ABIN1451835 : Suwanichkul, Boisclair, Olney, Durham, Powell: Conservation of a growth hormone-responsive promoter element in the human and mouse acid-labile subunit genes. in Endocrinology 2000 (PubMed)
    Show all 2 references for ABIN1451835

  2. Cow (Bovine) Polyclonal IGFALS Primary Antibody for WB - ABIN2775292 : Heath, Argente, Barrios, Pozo, Díaz-González, Martos-Moreno, Caimari, Gracia, Campos-Barros: Primary acid-labile subunit deficiency due to recessive IGFALS mutations results in postnatal growth deficit associated with low circulating insulin growth factor (IGF)-I, IGF binding protein-3 levels, and hyperinsulinemia. in The Journal of clinical endocrinology and metabolism 2008 (PubMed)

  3. Human Polyclonal IGFALS Primary Antibody for FACS, IHC (p) - ABIN391690 : Leong, Baxter, Camerato, Dai, Wood: Structure and functional expression of the acid-labile subunit of the insulin-like growth factor-binding protein complex. in Molecular endocrinology (Baltimore, Md.) 1992 (PubMed)

More Antibodies against Insulin-Like Growth Factor Binding Protein, Acid Labile Subunit Interaction Partners

Human Insulin-Like Growth Factor Binding Protein, Acid Labile Subunit (IGFALS) interaction partners

  1. Mutations in the IGFALS and low expression level of IGFALS proteins lead to growth and development retardation. [Review]

  2. A novel homozygous mutation in IGFALS, c.380T>C (p.L127P), was identified in two siblings of a consanguineous family.

  3. Heterozygous IGFALS gene variants could be responsible for short stature in a subset of idiopathic short stature children with diminished levels of IGF-1, IGFBP-3 and ALS.

  4. These gene dosage effects demonstrate that one functional IGFALS allele is insufficient to maintain normal ALS levels, endocrine IGF-I (show IGF1 Antibodies) action, full growth potential, muscle size, and periosteal expansion.

  5. functional analysis supported a tumor-suppressive function for IGFALS in vitro.

  6. Heterozygous STAT5B (show STAT5B Antibodies) mutations, with or without heterozygous IGFALS defects, may be associated with growth hormone (show GH1 Antibodies) insensitivity.

  7. low circulating IGF-I (show IGF1 Antibodies) levels due to Acid-Labile Subunit deficiency in adulthood are not associated with early development of atherosclerosis and impaired heart function.

  8. D440N mutation in ALS generates a hyperglycosylated form with impaired secretion and complex formation, potentially leading to dysregulation of endocrine IGF, thus contributing to growth retardation

  9. Common genetic variation in the IGF1 (show IGF1 Antibodies) and SSTR5 (show SSTR5 Antibodies) genes seems to influence circulating IGF-I (show IGF1 Antibodies) levels

  10. We describe that the human placenta expresses the mRNA and the protein for ALS, and we observed an increase in ALS mRNA expression and protein content in small compared with appropriate for gestational age placentas.

Mouse (Murine) Insulin-Like Growth Factor Binding Protein, Acid Labile Subunit (IGFALS) interaction partners

  1. the Igfals gene has a role in skeletal response of male mice to anabolic hormone therapy

  2. A modest reduction in post-natal growth in the null ALS mice and in the ALS-deficient patients was observed

Pig (Porcine) Insulin-Like Growth Factor Binding Protein, Acid Labile Subunit (IGFALS) interaction partners

  1. The isolation and characterization of the IGFALS gene, including its expression profile and variations, are reported.

Cow (Bovine) Insulin-Like Growth Factor Binding Protein, Acid Labile Subunit (IGFALS) interaction partners

  1. Polymorphisms in the IGFALS gene are associated with growth traits in beef cattle (Bos taurus) in China.

Insulin-Like Growth Factor Binding Protein, Acid Labile Subunit (IGFALS) Antigen Profile

Protein Summary

The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty. Three transcript variants encoding two different isoforms have been found for this gene.

Gene names and symbols associated with IGFALS

  • insulin-like growth factor binding protein, acid labile subunit (IGFALS) antibody
  • insulin-like growth factor binding protein, acid labile subunit (igfals) antibody
  • insulin-like growth factor binding protein, acid labile subunit (Igfals) antibody
  • Albs antibody
  • Als antibody
  • mKIAA4111 antibody

Protein level used designations for IGFALS

insulin-like growth factor binding protein, acid labile subunit , insulin-like growth factor-binding protein complex acid labile subunit-like , insulin-like growth factor binding protein complex acid labile chain , insulin-like growth factor-binding protein complex acid labile subunit , insulin-like growth factor binding protein complex acid-labile subunit , insulin-like growth factor-binding protein complex acid labile chain , insulin-like growth factor binding protein, acid-labile subunit

GENE ID SPECIES
467869 Pan troglodytes
490069 Canis lupus familiaris
100101314 Xenopus laevis
100414686 Callithrix jacchus
3483 Homo sapiens
16005 Mus musculus
79438 Rattus norvegicus
397322 Sus scrofa
532494 Bos taurus
427649 Gallus gallus
Selected quality suppliers for anti-Insulin-Like Growth Factor Binding Protein, Acid Labile Subunit (IGFALS) Antibodies
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