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anti-Integrin, alpha 5 (Fibronectin Receptor, alpha Polypeptide) (ITGA5) Antibodies

The product of ITGA5 belongs to the integrin alpha chain family. Additionally we are shipping ITGA5 Proteins (17) and ITGA5 Kits (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ITGA5 16402 P11688
ITGA5 3678 P08648
ITGA5 315346  
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Top anti-ITGA5 Antibodies at antibodies-online.com

Showing 10 out of 402 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Mouse Rat FITC FACS Staining of mouse peripheral blood lymphocytes with RAT ANTI MOUSE CD49e: FITC (ABIN119996). 0.1 mg Log in to see 6 to 8 Days
$253.00
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of ITGA5 (arrow) using rabbit polyclonal ITGA5 Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the ITGA5 gene. ITGA5 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ITGA5 Antibody (Center) for immunohistochemistry.  Clinical relevance has not been evaluated. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue reacted with CD49e / ITGA5 Antibody (Center) followed by peroxidase conjugation of the secondary antibody and DAB staining. Western blot analysis of CD49e / ITGA5 Antibody (Center) in human uterine tumor and mouse bladder tissue lysates (35ug/lane). This demonstrates the ITGA5 antibody detected the ITGA5 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated FACS, WB Western blot analysis of CD49e antibody (C-term) (ABIN389403) in mouse bladder tissue lysates (35 µg/lane). CD49e (arrow) was detected using the purified polyclonal antibody. Flow cytometric analysis of HepG2 cells using CD49e Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Mouse Rat Un-conjugated FACS, IHC (fro) Staining of mouse peripheral blood lymphocytes with RAT ANTI MOUSE CD49e (ABIN120000). 0.1 mg Log in to see 6 to 8 Days
$253.00
Details
Human Rabbit Un-conjugated FACS, WB ITGA5 Antibody (C-term) (ABIN651710) western blot analysis in mouse bladder tissue lysates (15 µg/lane). This demonstrates the ITGA5 antibody detected ITGA5 protein (arrow). ITGA5 Antibody (C-term) (ABIN651710) flow cytometric analysis of CEM cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Dog Mouse Un-conjugated FACS, IHC (fro), IP   25 μg Log in to see 6 to 8 Days
$176.00
Details
Human Mouse Un-conjugated IF, IP, IHC, WB Western blot analysis of CD49e (Integrin alpha5) on a HeLa cell lysate (Human cervical epitheloid carcinoma, ATCC CCL-2.2). Lane 1: 1:5000, lane 2: 1:10,000, lane 3: 1:20,000 dilution of the anti-human CD49e antibody. 50 μg Log in to see 5 to 6 Days
$205.42
Details
Human Mouse Un-conjugated FACS, IHC, ELISA, WB Figure 1: Flow cytometric analysis of Hela cells using ITGA5 mouse mAb (green) and negative control (purple) . Figure 2: Immunohistochemical analysis of paraffin-embedded human Placenta tissues using ITGA5 mouse mAb 100 μL Log in to see 3 to 4 Days
$393.80
Details
Mouse Rat PE FACS 50 μg Log in to see 10 to 12 Days
$114.15
Details

ITGA5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-ITGA5 Antibodies

  1. Mouse (Murine) Monoclonal ITGA5 Primary Antibody for FACS - ABIN2663509 : Hemler: VLA proteins in the integrin family: structures, functions, and their role on leukocytes. in Annual review of immunology 1990 (PubMed)
    Show all 9 references for ABIN2663509

  2. Dog (Canine) Monoclonal ITGA5 Primary Antibody for FACS, IHC (fro) - ABIN319772 : Shen, Stewart, Wayner, Carter, Wilkins: Antibodies to different members of the beta 1 (CD29) integrins induce homotypic and heterotypic cellular aggregation. in Cellular immunology 1991 (PubMed)
    Show all 6 references for ABIN319772

  3. Human Monoclonal ITGA5 Primary Antibody for IF, IP - ABIN968077 : Alahari, Lee, Juliano: Nischarin, a novel protein that interacts with the integrin alpha5 subunit and inhibits cell migration. in The Journal of cell biology 2001 (PubMed)
    Show all 5 references for ABIN968077

  4. Human Monoclonal ITGA5 Primary Antibody for FACS, IHC - ABIN969221 : Jones, Gockerman, Busby, Wright, Clemmons: Insulin-like growth factor binding protein 1 stimulates cell migration and binds to the alpha 5 beta 1 integrin by means of its Arg-Gly-Asp sequence. in Proceedings of the National Academy of Sciences of the United States of America 1993 (PubMed)
    Show all 5 references for ABIN969221

  5. Human Polyclonal ITGA5 Primary Antibody for FACS, WB - ABIN389403 : Boehmler, Drost, Jaggy, Seitz, Wiesner, Denzlinger, Kanz, Möhle: The CysLT1 ligand leukotriene D4 supports alpha4beta1- and alpha5beta1-mediated adhesion and proliferation of CD34+ hematopoietic progenitor cells. in Journal of immunology (Baltimore, Md. : 1950) 2009 (PubMed)
    Show all 3 references for ABIN389403

  6. Human Polyclonal ITGA5 Primary Antibody for EIA, IHC (p) - ABIN951340 : Fang, Yao, Xiong, Zhang, Liu, Li, Zhang, Wan: Functional elucidation and methylation-mediated downregulation of ITGA5 gene in breast cancer cell line MDA-MB-468. in Journal of cellular biochemistry 2010 (PubMed)
    Show all 3 references for ABIN951340

  7. Mouse (Murine) Monoclonal ITGA5 Primary Antibody for FACS - ABIN119996 : Cukierman, Pankov, Stevens, Yamada: Taking cell-matrix adhesions to the third dimension. in Science (New York, N.Y.) 2001 (PubMed)
    Show all 3 references for ABIN119996

  8. Mouse (Murine) Monoclonal ITGA5 Primary Antibody for FACS, IHC (fro) - ABIN120000 : Kinashi, Springer: Adhesion molecules in hematopoietic cells. in Blood cells 1995 (PubMed)
    Show all 2 references for ABIN120000

  9. Human Polyclonal ITGA5 Primary Antibody for IHC (p), WB - ABIN656138 : Hu, Fang, Wang, Luk, Thamphiwatana, Dehaini, Nguyen, Angsantikul, Wen, Kroll, Carpenter, Ramesh, Qu, Patel, Zhu, Shi, Hofman, Chen, Gao, Zhang, Chien, Zhang: Nanoparticle biointerfacing by platelet membrane cloaking. in Nature 2015 (PubMed)

  10. Human Polyclonal ITGA5 Primary Antibody for FACS, WB - ABIN651710 : Jiang, Sun, Li, Hu, Zhou, Jiang, Xu: Calycosin-7-O-?-D-glucoside promotes oxidative stress-induced cytoskeleton reorganization through integrin-linked kinase signaling pathway in vascular endothelial cells. in BMC complementary and alternative medicine 2015 (PubMed)

More Antibodies against ITGA5 Interaction Partners

Mouse (Murine) Integrin, alpha 5 (Fibronectin Receptor, alpha Polypeptide) (ITGA5) interaction partners

  1. Gdf-5 (show GDF5 Antibodies) induced the expression of the alpha5 sub-unit, while Bmp-7 (show BMP7 Antibodies) induced the expression of the alphaV sub-unit.

  2. EGFR (show EGFR Antibodies) activation can be regulated by the N-glycosylation of integrin alpha5, which is a novel molecular paradigm for the cross-talk between integrins and growth factor receptors

  3. An (as yet unknown) integrin alpha5-dependent signal extrinsic to the pharyngeal endothelium mediates the formation of the 4th pharyngeal arch arteries through fibronectin (show FN1 Antibodies).

  4. Suggest that alpha5beta1-mediated cross-talk between fibronectin (show FN1 Antibodies) and oxLDL regulates inflammation in early atherogenesis and that therapeutics that inhibit alpha5 integrins may reduce inflammation without adversely affecting plaque structure.

  5. our data point to a potential role for the fibronectin (show FN1 Antibodies)-alpha5beta1 integrin interaction in promoting vascular remodeling during demyelinating disease

  6. high expression of the ppGalNAc-T13 (show GALNT13 Antibodies) gene generates tTn (show TTN Antibodies) antigen on Syndecan 1 (show SDC1 Antibodies), leading to enhanced invasion and metastasis via the formation of a complex consisting of integrin alpha5beta1, Syndecan 1 (show SDC1 Antibodies), and MMP-9 (show MMP9 Antibodies) in the glycolipid-enriched microdomain/rafts.

  7. Fibronectin (show FN1 Antibodies) and integrin alpha5beta1 have critical roles in mouse embryogenesis

  8. It was found that binding between Porphyromonas gingivalis fimbriae and integrin alpha5beta1 on osteoblasts, and subsequent peripheral condensation of actin, are essential for entry of Porphyromonas gingivalis into osteoblasts.

  9. Our study unveils a previously unidentified role of alpha5beta1 integrin as an intermediate signaling molecule in neurotoxic prion (show PRNP Antibodies) peptides-microglia interactions.

  10. Fibroblasts require Mena for multiple integrin alpha5beta1-dependent processes involving bidirectional interactions between the extracellular matrix and cytoplasmic focal adhesion proteins.

Human Integrin, alpha 5 (Fibronectin Receptor, alpha Polypeptide) (ITGA5) interaction partners

  1. ITGA5 plays an important role in maintaining and regulating the normal migration capacity of dental pulp stem cells.

  2. IGFBP-2 (show IGFBP2 Antibodies) enhances endothelial progenitor cell adhesion to HUVECs via Integrin alpha5beta1. The RGD motif in the IGFBP-2 (show IGFBP2 Antibodies) C-domain is required for interaction with integrin alpha5beta1.

  3. knockdown of PTTG1 (show PTTG1 Antibodies) increased expression of integrin alpha 4 (ITGA4 (show ITGA4 Antibodies)), ITGA5, and integrin beta 1 (ITGB1 (show ITGB1 Antibodies)); otherwise, RhoA (show RHOA Antibodies) expression was significantly decreased

  4. Genetic and Immunohistochemical Expression of Integrins ITGAV (show ITGAV Antibodies), ITGA6 (show ITGA6 Antibodies), and ITGA3 (show ITGA3 Antibodies) As Prognostic Factor for Colorectal Cancer

  5. Data show that the fold changes of very late antigen 5 VLA-5 (integrin alpha-5 beta-1) in CD14 (show NDUFA2 Antibodies)+ monocytes were higher than those observed for THP-1 (show GLI2 Antibodies) cells.

  6. Data suggest that reduced ability of AnxA6 (show ANXA6 Antibodies)-expressing cells to migrate is associated with decreased cell surface expression of integrins alphaVbeta3 and alpha5beta1.

  7. Data suggest that the binding, but not the internalization of photoreceptor outer segments (POS) confers protective effects on retinal pigment epithelium (RPE) cells through the alphavbeta5 integrin/focal adhesion kinase (FAK)/PGC-1alpha pathway.

  8. alpha5beta1 and alphavbeta3 each mediate actin cytoskeletal remodeling in response to stiffening or cyclic stretching of the extracellular matrix.

  9. Data show that a small molecule inhibitor of the MYC (show MYC Antibodies) transcription factor can be an effective anticancer agent when delivered using a integrin alphavbeta3 (show ITGAV Antibodies) and VLA-4-targeted nanotherapy approach.

  10. Data suggest that Entamoeba histolytica-macrophage contact triggers recruitment of alpha5beta1 integrin (ITGA5/ITGB1 (show ITGB1 Antibodies)) and NLRP3 (show NLRP3 Antibodies) into intercellular junction, where ITGA5/ITGB1 (show ITGB1 Antibodies) undergoes activation by cysteine protease (show CTSB Antibodies) on parasite surface.

Cow (Bovine) Integrin, alpha 5 (Fibronectin Receptor, alpha Polypeptide) (ITGA5) interaction partners

  1. Putative function of fibronectin (show FN1 Antibodies) and its receptor (integrin alpha(5)beta(1)) in male and female gametes during bovine fertilization in vitro.

  2. Results indicate that XIAP (show XIAP Antibodies) stabilizes the alpha(5)-integrin-associated focal adhesion complex, thereby further regulating endothelial cell adhesion and migration.

  3. alphavbeta3 integrin engagement in vascular endothelium regulates Ca2 (show CA2 Antibodies)+-dependent K+ current

  4. Flow induced alpha2beta1 activation in cells on collagen, but not on fibronectin or fibrinogen. Conversely, alpha5beta1 and alphavbeta3 are activated on fibronectin and fibrinogen, but not collagen.

ITGA5 Antigen Profile

Protein Summary

The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.

Gene names and symbols associated with ITGA5

  • integrin, alpha 5 (fibronectin receptor, alpha polypeptide) (ITGA5) antibody
  • integrin alpha 5 (fibronectin receptor alpha) (Itga5) antibody
  • integrin, alpha 5 (fibronectin receptor, alpha polypeptide) (Itga5) antibody
  • CD49e antibody
  • FNRA antibody
  • ITGA5 antibody
  • Itga5_retired antibody
  • VLA5 antibody
  • VLA5A antibody

Protein level used designations for ITGA5

integrin, alpha 5 (fibronectin receptor, alpha polypeptide) , CD49 antigen-like family member E , fibronectin receptor alpha polypeptide , fibronectin receptor subunit alpha , integrin alpha-5 , integrin alpha-F , VLA-5 , fibronectin receptor, alpha subunit , very late activation protein 5, alpha subunit , integrin alpha 5 (fibronectin receptor alpha)

GENE ID SPECIES
486493 Canis lupus familiaris
100606925 Nomascus leucogenys
16402 Mus musculus
3678 Homo sapiens
315346 Rattus norvegicus
281873 Bos taurus
Selected quality suppliers for anti-ITGA5 (ITGA5) Antibodies
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