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The product of ITGA5 belongs to the integrin alpha chain family. Additionally we are shipping ITGA5 Proteins (18) and ITGA5 Kits (10) and many more products for this protein.
Showing 10 out of 413 products:
Dog (Canine) Monoclonal ITGA5 Primary Antibody for FACS, IHC (fro) - ABIN319772
Shen, Stewart, Wayner, Carter, Wilkins: Antibodies to different members of the beta 1 (CD29) integrins induce homotypic and heterotypic cellular aggregation. in Cellular immunology 1991
Show all 6 references for ABIN319772
Human Monoclonal ITGA5 Primary Antibody for IF, IP - ABIN968077
Alahari, Lee, Juliano: Nischarin, a novel protein that interacts with the integrin alpha5 subunit and inhibits cell migration. in The Journal of cell biology 2001
Show all 5 references for ABIN968077
Human Monoclonal ITGA5 Primary Antibody for FACS, IHC - ABIN969221
Jones, Gockerman, Busby, Wright, Clemmons: Insulin-like growth factor binding protein 1 stimulates cell migration and binds to the alpha 5 beta 1 integrin by means of its Arg-Gly-Asp sequence. in Proceedings of the National Academy of Sciences of the United States of America 1993
Show all 5 references for ABIN969221
Mouse (Murine) Monoclonal ITGA5 Primary Antibody for FACS - ABIN119996
Cukierman, Pankov, Stevens, Yamada: Taking cell-matrix adhesions to the third dimension. in Science (New York, N.Y.) 2001
Show all 3 references for ABIN119996
Human Polyclonal ITGA5 Primary Antibody for EIA, IHC (p) - ABIN951340
Fang, Yao, Xiong, Zhang, Liu, Li, Zhang, Wan: Functional elucidation and methylation-mediated downregulation of ITGA5 gene in breast cancer cell line MDA-MB-468. in Journal of cellular biochemistry 2010
Show all 3 references for ABIN951340
Human Polyclonal ITGA5 Primary Antibody for FACS, WB - ABIN389403
Boehmler, Drost, Jaggy, Seitz, Wiesner, Denzlinger, Kanz, Möhle: The CysLT1 ligand leukotriene D4 supports alpha4beta1- and alpha5beta1-mediated adhesion and proliferation of CD34+ hematopoietic progenitor cells. in Journal of immunology (Baltimore, Md. : 1950) 2009
Show all 3 references for ABIN389403
Mouse (Murine) Monoclonal ITGA5 Primary Antibody for FACS, IHC (fro) - ABIN120000
Kinashi, Springer: Adhesion molecules in hematopoietic cells. in Blood cells 1995
Show all 2 references for ABIN120000
Human Polyclonal ITGA5 Primary Antibody for IHC (p), WB - ABIN656138
Hu, Fang, Wang, Luk, Thamphiwatana, Dehaini, Nguyen, Angsantikul, Wen, Kroll, Carpenter, Ramesh, Qu, Patel, Zhu, Shi, Hofman, Chen, Gao, Zhang, Chien, Zhang: Nanoparticle biointerfacing by platelet membrane cloaking. in Nature 2015
Human Monoclonal ITGA5 Primary Antibody for FACS - ABIN4897552
Hosomi, Oshitani, Kamata, Sogawa, Okazaki, Tanigawa, Yamagami, Watanabe, Tominaga, Watanabe, Fujiwara, Maeda, Hirakawa, Arakawa: Increased numbers of immature plasma cells in peripheral blood specifically overexpress chemokine receptor CXCR3 and CXCR4 in patients with ulcerative colitis. in Clinical and experimental immunology 2011
Human Polyclonal ITGA5 Primary Antibody for FACS, WB - ABIN651710
Jiang, Sun, Li, Hu, Zhou, Jiang, Xu: Calycosin-7-O-?-D-glucoside promotes oxidative stress-induced cytoskeleton reorganization through integrin-linked kinase signaling pathway in vascular endothelial cells. in BMC complementary and alternative medicine 2015
Gdf-5 (show GDF5 Antibodies) induced the expression of the alpha5 sub-unit, while Bmp-7 (show BMP7 Antibodies) induced the expression of the alphaV sub-unit.
EGFR (show EGFR Antibodies) activation can be regulated by the N-glycosylation of integrin alpha5, which is a novel molecular paradigm for the cross-talk between integrins and growth factor receptors
An (as yet unknown) integrin alpha5-dependent signal extrinsic to the pharyngeal endothelium mediates the formation of the 4th pharyngeal arch arteries through fibronectin (show FN1 Antibodies).
Suggest that alpha5beta1-mediated cross-talk between fibronectin (show FN1 Antibodies) and oxLDL regulates inflammation in early atherogenesis and that therapeutics that inhibit alpha5 integrins may reduce inflammation without adversely affecting plaque structure.
our data point to a potential role for the fibronectin (show FN1 Antibodies)-alpha5beta1 integrin interaction in promoting vascular remodeling during demyelinating disease
high expression of the ppGalNAc-T13 (show GALNT13 Antibodies) gene generates tTn (show TTN Antibodies) antigen on Syndecan 1 (show SDC1 Antibodies), leading to enhanced invasion and metastasis via the formation of a complex consisting of integrin alpha5beta1, Syndecan 1 (show SDC1 Antibodies), and MMP-9 (show MMP9 Antibodies) in the glycolipid-enriched microdomain/rafts.
Fibronectin (show FN1 Antibodies) and integrin alpha5beta1 have critical roles in mouse embryogenesis
It was found that binding between Porphyromonas gingivalis fimbriae and integrin alpha5beta1 on osteoblasts, and subsequent peripheral condensation of actin, are essential for entry of Porphyromonas gingivalis into osteoblasts.
Our study unveils a previously unidentified role of alpha5beta1 integrin as an intermediate signaling molecule in neurotoxic prion (show PRNP Antibodies) peptides-microglia interactions.
Fibroblasts require Mena for multiple integrin alpha5beta1-dependent processes involving bidirectional interactions between the extracellular matrix and cytoplasmic focal adhesion proteins.
In colorectal cancer cells, miR (show MLXIP Antibodies)-130b directly targeted the 3' untranslated region (3'UTR (show UTS2R Antibodies)) region of integrin alpha5 gene, which encodes a key molecule involved in cell motility. TGF-beta1 (show TGFB1 Antibodies) acted through miR (show MLXIP Antibodies)-130b to promote integrin alpha5 expression, resulting in the enhanced migration of CRC (show CALR Antibodies) cells.
upregulation of miR (show MLXIP Antibodies)-31 targeting ITGA5 may suppress tumor cell invasion and metastasis by indirectly regulating PI3K (show PIK3CA Antibodies)/AKT (show AKT1 Antibodies) signaling pathway in human SGC7901 GC cells
ITGA5 plays an important role in maintaining and regulating the normal migration capacity of dental pulp stem cells.
IGFBP-2 (show IGFBP2 Antibodies) enhances endothelial progenitor cell adhesion to HUVECs via Integrin alpha5beta1. The RGD motif in the IGFBP-2 (show IGFBP2 Antibodies) C-domain is required for interaction with integrin alpha5beta1.
knockdown of PTTG1 (show PTTG1 Antibodies) increased expression of integrin alpha 4 (ITGA4 (show ITGA4 Antibodies)), ITGA5, and integrin beta 1 (ITGB1 (show ITGB1 Antibodies)); otherwise, RhoA (show RHOA Antibodies) expression was significantly decreased
Genetic and Immunohistochemical Expression of Integrins ITGAV (show ITGAV Antibodies), ITGA6 (show ITGA6 Antibodies), and ITGA3 (show ITGA3 Antibodies) As Prognostic Factor for Colorectal Cancer
Data show that the fold changes of very late antigen 5 VLA-5 (integrin alpha-5 beta-1) in CD14 (show NDUFA2 Antibodies)+ monocytes were higher than those observed for THP-1 (show GLI2 Antibodies) cells.
Data suggest that reduced ability of AnxA6 (show ANXA6 Antibodies)-expressing cells to migrate is associated with decreased cell surface expression of integrins alphaVbeta3 and alpha5beta1.
Data suggest that the binding, but not the internalization of photoreceptor outer segments (POS) confers protective effects on retinal pigment epithelium (RPE) cells through the alphavbeta5 integrin/focal adhesion kinase (FAK)/PGC-1alpha pathway.
alpha5beta1 and alphavbeta3 each mediate actin cytoskeletal remodeling in response to stiffening or cyclic stretching of the extracellular matrix.
Putative function of fibronectin (show FN1 Antibodies) and its receptor (integrin alpha(5)beta(1)) in male and female gametes during bovine fertilization in vitro.
Results indicate that XIAP (show XIAP Antibodies) stabilizes the alpha(5)-integrin-associated focal adhesion complex, thereby further regulating endothelial cell adhesion and migration.
alphavbeta3 integrin engagement in vascular endothelium regulates Ca2 (show CA2 Antibodies)+-dependent K+ current
Flow induced alpha2beta1 activation in cells on collagen, but not on fibronectin or fibrinogen. Conversely, alpha5beta1 and alphavbeta3 are activated on fibronectin and fibrinogen, but not collagen.
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
, CD49 antigen-like family member E
, fibronectin receptor alpha polypeptide
, fibronectin receptor subunit alpha
, integrin alpha-5
, integrin alpha-F
, fibronectin receptor, alpha subunit
, very late activation protein 5, alpha subunit
, integrin alpha 5 (fibronectin receptor alpha)