ITGA5 antibody
Quick Overview for ITGA5 antibody (ABIN7267936)
Target
See all ITGA5 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purpose
- Integrin alpha 5 (ITGA5/CD49e) Rabbit mAb
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Cross-Reactivity
- Human, Mouse, Rat
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Characteristics
- Monoclonal Antibodies
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Purification
- Affinity purification
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Immunogen
- A synthesized peptide derived from human Integrin alpha 5 (ITGA5/CD49e) (ITGA5/CD49e)
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IP,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- ITGA5 (Integrin, alpha 5 (ITGA5))
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Alternative Name
- ITGA5
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Background
- The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015],CD49e,FNRA,VLA-5,VLA5A,Integrin alpha 5,ITGA5,CDs,Cell Adhesion,Cell Biology & Developmental Biology,Cytoskeleton,Endothelial Progenitors,G protein signaling,G protein signaling_G-Protein-Coupled Receptors Signaling to MAPK/Erk,Hematopoietic Progenitors,Immunology & Inflammation,MAPK-Erk Signaling Pathway,PI3K-Akt Signaling Pathway,Signal Transduction,Stem Cells,ITGA5
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Molecular Weight
- 150kDa
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Gene ID
- 3678
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UniProt
- P08648
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Pathways
- Integrin Complex
Target
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