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Inter alpha Globulin Inhibitor H5 Proteins (ITIH5)

ITIH5 encodes a heavy chain component of one of the inter-alpha-trypsin inhibitor (ITI) family members. Additionally we are shipping ITIH5 Antibodies (27) and ITIH5 Kits (8) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ITIH5 209378 Q8BJD1
ITIH5 80760 Q86UX2
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Top ITIH5 Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Human His-SUMO Tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 9 to 11 Days
$506.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 11 to 13 Days
$739.20
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 9 to 19 Days
$920.54
Details

ITIH5 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human
,

More Proteins for Inter alpha Globulin Inhibitor H5 (ITIH5) Interaction Partners

Mouse (Murine) Inter alpha Globulin Inhibitor H5 (ITIH5) interaction partners

  1. indicate an additional and specific role of this gene in the female reproductive tract, and furthermore reinforces ITIH5 as a putative candidate gene for MRKH syndrome.

Human Inter alpha Globulin Inhibitor H5 (ITIH5) interaction partners

  1. ITIH5 may be a novel putative tumor suppressor gene in NSCLC with a potential molecular significance in the squamoid ADC (show ADC Proteins) subtype and further clinical impact for risk stratification of adenocarcinoma patients.

  2. Hence, we can strengthen the presumption that ITIH5 may constitute a novel regulatory molecule of the human skin that could play an important role in in fl ammation via its interaction with hyaluronic acid.

  3. ITIH5 expression is decreased in gastric cancer and that low expression of this protein is associated with poor clinical outcome.

  4. ITIH5 is a novel putative tumor suppressor gene in colon cancer with a potential impact in the CIMP-related pathway.

  5. Tumor-specific methylation of the three-gene panel (ITIH5, DKK3, and RASSF1A (show RASSF1 Proteins)) might be a valuable biomarker for the early detection of breast cancer.

  6. provide evidence that down-regulation of ITIH5 by aberrant DNA hypermethylation may provoke invasive phenotypes in human bladder cancer

  7. ITIH5 gene expression is regulated both by obesity and by the region between visceral and subcutaneous adipose tissue.

  8. ITIH-5 is highly expressed in sc adipose tissue, increased in obesity, down regulated after weight loss, and associated with measures of body size and metabolism.

  9. expression is consistantly lost or strongly downregulated in invasive ductal carcinoma; proposed that loss of ITIH5 expression may be involved in breast cancer development

  10. Promoter methylation-mediated loss of ITIH5 expression is associated with unfavourable outcome in breast cancer patients.

ITIH5 Protein Profile

Protein Summary

This gene encodes a heavy chain component of one of the inter-alpha-trypsin inhibitor (ITI) family members. ITI proteins are involved in extracellular matrix stabilization and in the prevention of tumor metastasis. They are also structurally related plasma serine protease inhibitors and are composed of a light chain and varying numbers of heavy chains. This family member is thought to function as a tumor suppressor in breast and thyroid cancers. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with ITIH5

  • inter-alpha (globulin) inhibitor H5 (Itih5)
  • inter-alpha-trypsin inhibitor heavy chain family, member 5 (ITIH5)
  • 4631408O11Rik protein
  • 5430408M01Rik protein
  • E130106B02 protein
  • ITI-HC5 protein

Protein level used designations for ITIH5

ITI heavy chain H5 , ITI-HC5 , inter-alpha trypsin inhibitor heavy chain precursor 5 , inter-alpha-inhibitor heavy chain 5 , inter-alpha-trypsin inhibitor heavy chain H5 , inter-alpha (globulin) inhibitor H5 , inter-alpha trypsin inhibitor heavy chain 5

GENE ID SPECIES
209378 Mus musculus
80760 Homo sapiens
534787 Bos taurus
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