You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Interferon Regulatory Factor 6 (IRF6) Antibodies

IRF6 encodes a member of the interferon regulatory transcription factor (IRF) family. Additionally we are shipping Interferon Regulatory Factor 6 Proteins (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
IRF6 3664 O14896
IRF6 54139 P97431
IRF6 364081  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-Interferon Regulatory Factor 6 Antibodies at antibodies-online.com

Showing 10 out of 84 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated IHC, WB WB Suggested Anti-IRF6 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1... Immunohistochemistry with Placenta tissue at an antibody concentration... 100 μL Log in to see 2 to 3 Days
$289.00
Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-IRF6 Antibody Titration: 2.5ug/mlPositive Control: J... WB Suggested Anti-IRF6  Antibody Titration: 2.5 µg/mL  Positive Contro... 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Goat Un-conjugated IHC, ELISA, WB ABIN184730 staining (0.2µg/ml) of Human Ovary lysate (RIPA buffer, 35µ... 100 μg Log in to see 4 to 5 Days
$318.20
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-IRF6 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1... 100 μL Log in to see 2 to 3 Days
$289.00
Details
Chicken Rabbit Un-conjugated WB Host: Rabbit  Target Name: IRF6  Sample Tissue: Human Adult Placenta  ... 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated FACS, IF, IHC, WB Anti-IRF6 mouse monoclonal antibody (ABIN2454894) immunofluorescent st... HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane... 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, IF, WB HEK293T cells transfected with either RC201579 overexpress plasmid (Re... Anti-IRF6 mouse monoclonal antibody (ABIN2454890) immunofluorescent st... 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane... 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, IF, IHC, WB Anti-IRF6 mouse monoclonal antibody (ABIN2454769) immunofluorescent st... Immunohistochemical staining of paraffin-embedded Human breast tissue ... 100 μL Log in to see 2 to 3 Days
$482.90
Details

IRF6 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,
, ,
Mouse (Murine) , , , ,
,
Rat (Rattus) , , , ,
, ,

Top referenced anti-Interferon Regulatory Factor 6 Antibodies

  1. Chicken Polyclonal IRF6 Primary Antibody for IHC, WB - ABIN2779406 : Iwata, Suzuki, Pelikan, Ho, Sanchez-Lara, Urata, Dixon, Chai: Smad4-Irf6 genetic interaction and TGFβ-mediated IRF6 signaling cascade are crucial for palatal fusion in mice. in Development (Cambridge, England) 2013 (PubMed)

  2. Human Polyclonal IRF6 Primary Antibody for IHC, ELISA - ABIN184730 : Kondo, Schutte, Richardson, Bjork, Knight, Watanabe, Howard, de Lima, Daack-Hirsch, Sander, McDonald-McGinn, Zackai, Lammer, Aylsworth, Ardinger, Lidral, Pober, Moreno, Arcos-Burgos, Valencia et al.: Mutations in IRF6 cause Van der Woude and popliteal pterygium syndromes. ... in Nature genetics 2002 (PubMed)

  3. Chicken Polyclonal IRF6 Primary Antibody for WB - ABIN2781490 : Beausoleil, Jedrychowski, Schwartz, Elias, Villén, Li, Cohn, Cantley, Gygi: Large-scale characterization of HeLa cell nuclear phosphoproteins. in Proceedings of the National Academy of Sciences of the United States of America 2004 (PubMed)

More Antibodies against Interferon Regulatory Factor 6 Interaction Partners

Human Interferon Regulatory Factor 6 (IRF6) interaction partners

  1. Mutations in IRF6 cause Van der Woude and popliteal pterygium syndrome and contribute to nonsyndromic cleft lip phenotypes but have not previously been associated with a PRS phenotype.

  2. IRF6 is likely to promote inflammation to P. gingivalis through its regulation of IL-36gamma.

  3. results confirmed the involvement of the IRF6 variants rs642961 and rs2235371 in the etiology of nonsyndromic cleft lip with or without cleft palate in a Chinese population.

  4. The IRF6 AP-2a binding site promoter polymorphism is associated with isolated oral clefts in Latvia.

  5. genetic polymorphism of the IRF6 gene is associated with increased risk of nsCLP in a Xinjiang Uyghur population.

  6. Data suggest that the toll like receptor 3 (TLR3 (show TLR3 Antibodies))-interferon regulatory factor 6 protein (IRF6)-interleukin-23 subunit p19 (p19 (show IL23A Antibodies))/EBI3 (show EBI3 Antibodies) protein axis may regulate keratinocyte functions in the skin.

  7. IRF6 acts as a positive regulator of proliferation and transformation in MCF10A cells downstream of Notch (show NOTCH1 Antibodies) signaling.

  8. The truncation of IRF6 also prevented the induction of its transactivator function by RIPK4 (show RIPK4 Antibodies).

  9. Our results showed that many CL/P candidate genes have relation with Irf6, and 9 of these genes, including Msx1 (show MSX1 Antibodies), Pvrl1 (show PVRL1 Antibodies), Pax9 (show PAX9 Antibodies), Jag2 (show JAG2 Antibodies), Irf6, Tgfb3 (show TGFB3 Antibodies), Rara (show RARA Antibodies), Gli2 (show GLI2 Antibodies), and Tgfb2 (show TGFB2 Antibodies), were enriched into the CL/P gene group.

  10. significant overrepresentation of tagSNP haplotype carrying rs642961 risk allele in most severe subphenotype of CL/P. recently shown that >80% of IRF6 mutations in syndromic CL/P occur on same haplotype. suggest IRF6 is marker of CL/P severity.

Zebrafish Interferon Regulatory Factor 6 (IRF6) interaction partners

  1. In zebrafish periderm, grainyhead-like 3 (grhl3 (show GRHL3 Antibodies)) (an ancient regulator of the epidermal permeability barrier), was identified as acting downstream of Irf6. Simultaneous inhibition of grhl1 (show GRHL1 Antibodies) and grhl3 (show GRHL3 Antibodies) disrupted periderm differentiation in zebrafish.

  2. analysis of zebrafish expression of IRF6

  3. These experiments reveal a conserved role for maternally-encoded Irf6 in differentiation of a simple epithelium in X. laevis and D. rerio.

Mouse (Murine) Interferon Regulatory Factor 6 (IRF6) interaction partners

  1. Irf6 is required for resistance to Lipopolysaccharides-induced endotoxic shock. In addition, Irf6-deficient bone marrow-derived neutrophils exhibited increased chemotactic index and velocity compared with wild-type cells in vitro.

  2. TGFbeta3 increases IRF6 expression and subsequently regulates SNAI2 (show SNAI2 Antibodies) expression; IRF6 appears to regulate epithelial mesenchymal transition during palatal fusion via SNAI2 (show SNAI2 Antibodies).

  3. Pvrl1 (show PVRL1 Antibodies) is a bona fide target gene of the transcription factor p63 (show CKAP4 Antibodies), whereas Pvrl4 (show PVRL4 Antibodies) regulation is linked to epidermal differentiation and is under Irf6

  4. Data suggest that Irf6 functions through the RhoA (show RHOA Antibodies) pathway to regulate cellular migration.

  5. These results support a role for IRF6 in brain morphometry and provide evidence for a potential genetic link to abnormal brain development in orofacial clefting.

  6. Irf6 plays important cell-autonomous and non-cell-autonomous roles in muscular differentiation and cytoskeletal formation in the tongue.

  7. Irf6 plays a critical role in regulating epithelial invagination

  8. IRF6 and SMAD4 (show SMAD4 Antibodies) synergistically regulate the fate of the medial edge epithelium (MEE), and TGFbeta (show TGFB1 Antibodies)-mediated Irf6 activity is responsible for MEE degeneration during palatal fusion in mice.

  9. Interaction between IRF6 and TGFA (show TGFA Antibodies) genes contribute to the risk of nonsyndromic cleft lip/palate.

  10. These data suggest that MCS9.7 enhancer activity is not sufficient to recapitulate IRF6 expression, and that p63 (show CKAP4 Antibodies) expression is not always necessary nor sufficient for transactivation of IRF6.

Interferon Regulatory Factor 6 (IRF6) Antigen Profile

Protein Summary

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with IRF6

  • interferon regulatory factor 6 (IRF6) antibody
  • interferon regulatory factor 6 (irf6) antibody
  • interferon regulatory factor 6 (Irf6) antibody
  • AI876454 antibody
  • DKFZp469E012 antibody
  • E230028I05Rik antibody
  • IRF6 antibody
  • LPS antibody
  • mirf6 antibody
  • OFC6 antibody
  • PIT antibody
  • PPS antibody
  • PPS1 antibody
  • VWS antibody
  • VWS1 antibody
  • xIRF-6 antibody
  • zgc:63500 antibody

Protein level used designations for IRF6

interferon regulatory factor 6 , interferon regulatory factor 6-like , IRF-6

GENE ID SPECIES
443083 Ovis aries
457701 Pan troglodytes
594908 Xenopus (Silurana) tropicalis
712958 Macaca mulatta
100174467 Pongo abelii
100402804 Callithrix jacchus
100594750 Nomascus leucogenys
3664 Homo sapiens
393570 Danio rerio
443771 Xenopus laevis
480015 Canis lupus familiaris
397521 Sus scrofa
614253 Bos taurus
54139 Mus musculus
364081 Rattus norvegicus
100349520 Oryctolagus cuniculus
419863 Gallus gallus
Selected quality suppliers for anti-Interferon Regulatory Factor 6 (IRF6) Antibodies
Did you look for something else?