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Interleukin 1 delta Proteins (FIL1d)

Is a highly and a specific antagonist of the IL-1 receptor-related protein 2-mediated response to interleukin 1 family member 9 (IL1F9). Additionally we are shipping Interleukin 1 delta Antibodies (71) and Interleukin 1 delta Kits (27) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
FIL1d 54450 Q9QYY1
FIL1d 26525 Q9UBH0
Rat FIL1d FIL1d 311783  
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Top Interleukin 1 delta Proteins at antibodies-online.com

Showing 10 out of 25 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated IL-36Ra (aa 3-156) (mouse) (rec.)  inhibits IL-36α, IL-36β, IL-36γ-dependent expression of IL-6 in mouse BMDCs.  Method: Bone marrow cells were differentiated into bone marrow-derived dendritic cells (BMDCs) using GM-CSF (20ng/ml) for 10 days. BMDCs were cultured with or without IL-36Ra, IL-36α, IL-36β, IL-36γ, or LPS at indicated concentrations for 72 h. Cell supernatants were then harvested and IL-6 levels determined by ELISA. 10 μg Log in to see 5 to 8 Days
$204.75
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 50 μg Log in to see 16 Days
$382.80
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated 50 μg Log in to see 16 Days
$382.80
Details
HOST_Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$880.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   10 μg Log in to see 5 to 8 Days
$204.75
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 2 to 3 Days
$630.00
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$968.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 5 to 6 Days
$698.62
Details

FIL1d Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)
,
Human ,
,

Top referenced Interleukin 1 delta Proteins

  1. Human FIL1d Protein expressed in Escherichia coli (E. coli) - ABIN2002130 : Smith, Renshaw, Ketchem, Kubin, Garka, Sims: Four new members expand the interleukin-1 superfamily. in The Journal of biological chemistry 2000 (PubMed)
    Show all 3 references for ABIN2002130

  2. Mouse (Murine) FIL1d Protein expressed in Escherichia coli (E. coli) - ABIN2007521 : Barton, Herbst, Bosisio, Higgins, Nicklin: A tissue specific IL-1 receptor antagonist homolog from the IL-1 cluster lacks IL-1, IL-1ra, IL-18 and IL-18 antagonist activities. in European journal of immunology 2001 (PubMed)
    Show all 3 references for ABIN2007521

More Proteins for Interleukin 1 delta (FIL1d) Interaction Partners

Mouse (Murine) Interleukin 1 delta (FIL1d) interaction partners

  1. Interleukin-36 (show IL1F6 Proteins) (IL-36) ligands require processing for full agonist (IL-36alpha, IL-36beta, and IL-36gamma) or antagonist (IL-36Ra) activity

  2. Transcripts for IL-1F5 are significantly increased in the involved skin of bi- and monotransgenic mice compared with their C57BL controls.

  3. IL-1F5 has unique loop conformations for receptor binding specificity

  4. IL-1F5 mediates anti-inflammatory effects through its ability to induce interleukin-4 (show IL4 Proteins) production, as a consequence of its interaction with orphan receptor (show NR1D2 Proteins) single Ig IL-1R-related molecule (SIGIRR)/TIR8 (show SIGIRR Proteins).

Human Interleukin 1 delta (FIL1d) interaction partners

  1. generalized pustular psoriasis and early onset, ever generalized pustular psoriasis (more than two attacks), ever acrodermatitis continua of Hallopeau, inverse psoriasis, and a family history of pustular psoriasis were associated with IL36RN mutation.

  2. IL36RN was identified as strong regulators of skin pathology in both lesional and non-lesional skin samples.

  3. IL36RN missense mutation was not associated with psoriasis.

  4. found 2 new variants and 4 known IL36RN variants in 29 generalized pustular psoriasis patients

  5. identified a novel IL36RN missense mutation, c.334G > A in exon 5, that caused p.E112K substitution and was located adjacent to a 113 amino acid residue in generalized pustular psoriasis

  6. The study found that IL36RN alleles define a generalized pustular psoriasis phenotype characterized by early onset, high risk of systemic inflammation, and low prevalence of psoriasis vulgaris.

  7. Individuals with IL36RN mutations are very susceptible to Generalized pustular psoriasis (GPP) or GPP-related generalized pustulosis induced by drugs. [review]

  8. We report two cases of impetigo herpetiformis with homozygous and heterozygous IL36RN mutations.

  9. IL36RN variants are unlikely to confer significant disease risk for psoriasis vulgaris.

  10. Acrodermatitis is a clinical phenotype of DITRA: evidence a variant of pustular psoriasis... recessively inherited mutations in the IL36RN gene, which encodes interleukin-36 receptor antagonist... the cause of familial GPP, a condition termed DITRA

Interleukin 1 delta (FIL1d) Protein Profile

Protein Summary

Is a highly and a specific antagonist of the IL-1 receptor-related protein 2-mediated response to interleukin 1 family member 9 (IL1F9). Could constitute part of an independent signaling system analogous to interleukin-1 alpha (IL-1A), beta (IL-1B) receptor agonist and interleukin-1 receptor type I (IL- 1R1), that is present in epithelial barriers and takes part in local inflammatory response.

Gene names and symbols associated with Interleukin 1 delta Proteins (FIL1d)

  • interleukin 1 family, member 5 (delta) (Il1f5)
  • interleukin 36 receptor antagonist (IL36RN)
  • interleukin 36 receptor antagonist (Il36rn)
  • AI413231 protein
  • FIL1 protein
  • FIL1(DELTA) protein
  • FIL1D protein
  • Fil1delta protein
  • Il-1h3 protein
  • Il1f5 protein
  • IL1HY1 protein
  • IL1L1 protein
  • IL1RP3 protein
  • IL36RA protein
  • IL36RN protein
  • PSORP protein

Protein level used designations for Interleukin 1 delta Proteins (FIL1d)

IL-1 delta , IL-1F5 , IL-1HY1 , IL-1L1 , interleukin 1 receptor antagonist homolog 1 , interleukin-1 HY1 , interleukin-1 delta , interleukin-1 family member 5 , interleukin-1 homolog 3 , interleukin-1-like protein 1 , interleukin-36 receptor antagonist protein , IL-1 related protein 3 , IL-1F5 (IL-1HY1, FIL1-delta, IL-1RP3, IL-1L1, IL-1-delta) , IL-1ra homolog 1 , IL1F5 (Canonical product IL-1F5a) , interleukin 1 family, member 5 (delta) , interleukin-1 receptor antagonist homolog 1

GENE ID SPECIES
54450 Mus musculus
26525 Homo sapiens
311783 Rattus norvegicus
518514 Bos taurus
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