Interleukin 1 delta Proteins (FIL1d)

Is a highly and a specific antagonist of the IL-1 receptor-related protein 2-mediated response to interleukin 1 family member 9 (IL1F9). Additionally we are shipping Interleukin 1 delta Antibodies (76) and Interleukin 1 delta Kits (24) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
FIL1d 54450 Q9QYY1
FIL1d 26525 Q9UBH0
Rat FIL1d FIL1d 311783  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top Interleukin 1 delta Proteins at antibodies-online.com

Showing 10 out of 28 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated 50 μg Log in to see 20 to 21 Days
$382.80
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated IL-36Ra (aa 3-156) (mouse) (rec.)  inhibits IL-36α, IL-36β, IL-36γ-dependent expression of IL-6 in mouse BMDCs.  Method: Bone marrow cells were differentiated into bone marrow-derived dendritic cells (BMDCs) using GM-CSF (20ng/ml) for 10 days. BMDCs were cultured with or without IL-36Ra, IL-36α, IL-36β, IL-36γ, or LPS at indicated concentrations for 72 h. Cell supernatants were then harvested and IL-6 levels determined by ELISA. 10 μg Log in to see 5 to 8 Days
$204.75
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 50 μg Log in to see 20 to 21 Days
$382.80
Details
HOST_Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 15 to 18 Days
$800.00
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated Validation with Western Blot 25 μg Log in to see 12 to 15 Days
$229.85
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 4 Days
$522.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 2 to 3 Days
$575.00
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details

FIL1d Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,
Human , ,
, ,

Top referenced Interleukin 1 delta Proteins

  1. Mouse (Murine) FIL1d Protein expressed in Escherichia coli (E. coli) - ABIN2007521 : Smith, Renshaw, Ketchem, Kubin, Garka, Sims: Four new members expand the interleukin-1 superfamily. in The Journal of biological chemistry 2000 (PubMed)
    Show all 3 references for 2007521

  2. Human FIL1d Protein expressed in Escherichia coli (E. coli) - ABIN2002130 : Barton, Herbst, Bosisio, Higgins, Nicklin: A tissue specific IL-1 receptor antagonist homolog from the IL-1 cluster lacks IL-1, IL-1ra, IL-18 and IL-18 antagonist activities. in European journal of immunology 2001 (PubMed)
    Show all 3 references for 2002130

More Proteins for Interleukin 1 delta (FIL1d) Interaction Partners

Mouse (Murine) Interleukin 1 delta (FIL1d) interaction partners

  1. Interleukin-36 (show IL1F6 Proteins) (IL-36) ligands require processing for full agonist (IL-36alpha, IL-36beta, and IL-36gamma) or antagonist (IL-36Ra) activity

  2. Transcripts for IL-1F5 are significantly increased in the involved skin of bi- and monotransgenic mice compared with their C57BL controls.

  3. IL-1F5 has unique loop conformations for receptor binding specificity

  4. IL-1F5 mediates anti-inflammatory effects through its ability to induce interleukin-4 (show IL4 Proteins) production, as a consequence of its interaction with orphan receptor (show NR1D2 Proteins) single Ig IL-1R-related molecule (SIGIRR)/TIR8 (show SIGIRR Proteins).

Human Interleukin 1 delta (FIL1d) interaction partners

  1. A study on the association of IL36RN mutations that affect protein expression and function with phenotype in patients with generalized pustular psoriasis.

  2. The findings indicate that IL36RN mutations do not seem to contribute to the pathogenesis of common, nonpustular forms of psoriasis, but to the rarer pustular manifestations such as GPP, acrodermatitis continua suppurativa of Hallopeau and acute generalized exanthematous pustulosis.

  3. Some cases of geographic tongue are caused by IL36RN mutations, while those lacking mutations are associated with an imbalance in expression between IL-36Ra and IL-36gamma proteins in tongue tissue.

  4. Study data and the previous European study suggest that palmoplantar pustulosis is not associated with mutations of the IL36RN gene.

  5. Case Report: short-term infliximab for treatment of juvenile generalized pustular psoriasis with IL36RN mutation.

  6. The authors present a case of strikingly distinct phenotypes seen in two IL36RN mutation carriers from the same nonconsanguineous pedigree. This mutation it appears may influence the age of onset.

  7. We identified a novel homozygous missense mutation in IL36RN in two siblings, and showed the molecular basis of the condition to be both distinct from psoriasis and distinct between the two families studied.

  8. generalized pustular psoriasis and early onset, ever generalized pustular psoriasis (more than two attacks), ever acrodermatitis continua of Hallopeau, inverse psoriasis, and a family history of pustular psoriasis were associated with IL36RN mutation.

  9. IL36RN was identified as strong regulators of skin pathology in both lesional and non-lesional skin samples.

  10. IL36RN missense mutation was not associated with psoriasis.

Interleukin 1 delta (FIL1d) Protein Profile

Protein Summary

Is a highly and a specific antagonist of the IL-1 receptor-related protein 2-mediated response to interleukin 1 family member 9 (IL1F9). Could constitute part of an independent signaling system analogous to interleukin-1 alpha (IL-1A), beta (IL-1B) receptor agonist and interleukin-1 receptor type I (IL- 1R1), that is present in epithelial barriers and takes part in local inflammatory response.

Gene names and symbols associated with Interleukin 1 delta Proteins (FIL1d)

  • interleukin 1 family, member 5 (delta) (Il1f5)
  • interleukin 36 receptor antagonist (IL36RN)
  • interleukin 36 receptor antagonist (Il36rn)
  • AI413231 protein
  • FIL1 protein
  • FIL1(DELTA) protein
  • FIL1D protein
  • Fil1delta protein
  • Il-1h3 protein
  • Il1f5 protein
  • IL1HY1 protein
  • IL1L1 protein
  • IL1RP3 protein
  • IL36RA protein
  • IL36RN protein
  • PSORP protein

Protein level used designations for Interleukin 1 delta Proteins (FIL1d)

IL-1 delta , IL-1F5 , IL-1HY1 , IL-1L1 , interleukin 1 receptor antagonist homolog 1 , interleukin-1 HY1 , interleukin-1 delta , interleukin-1 family member 5 , interleukin-1 homolog 3 , interleukin-1-like protein 1 , interleukin-36 receptor antagonist protein , IL-1 related protein 3 , IL-1F5 (IL-1HY1, FIL1-delta, IL-1RP3, IL-1L1, IL-1-delta) , IL-1ra homolog 1 , IL1F5 (Canonical product IL-1F5a) , interleukin 1 family, member 5 (delta) , interleukin-1 receptor antagonist homolog 1

GENE ID SPECIES
54450 Mus musculus
26525 Homo sapiens
311783 Rattus norvegicus
518514 Bos taurus
Selected quality suppliers for Interleukin 1 delta Proteins (FIL1d)
Did you look for something else?