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The protein encoded by IL13RA2 is closely related to Il13RA1, a subuint of the interleukin 13 receptor complex. Additionally we are shipping IL13RA2 Proteins (27) and IL13RA2 Kits (26) and many more products for this protein.
Showing 10 out of 111 products:
Human Monoclonal IL13RA2 Primary Antibody for IHC (fro), FACS - ABIN1383686
Joshi, Plautz, Puri: Interleukin-13 receptor alpha chain: a novel tumor-associated transmembrane protein in primary explants of human malignant gliomas. in Cancer research 2000
Show all 8 Pubmed References
Human Monoclonal IL13RA2 Primary Antibody for RNAi, ELISA - ABIN561476
Zeis, Graumann, Reynolds, Schaeren-Wiemers: Normal-appearing white matter in multiple sclerosis is in a subtle balance between inflammation and neuroprotection. in Brain : a journal of neurology 2007
Human Polyclonal IL13RA2 Primary Antibody for FACS - ABIN4896504
Biancheri, Di Sabatino, Ammoscato, Facciotti, Caprioli, Curciarello, Hoque, Ghanbari, Joe-Njoku, Giuffrida, Rovedatti, Geginat, Corazza, MacDonald: Absence of a role for interleukin-13 in inflammatory bowel disease. in European journal of immunology 2014
cigarette smoke extracts activate the PKA, CREB (show CREB1 Antibodies), and IL-13Ralpha2 axis in lung endothelial cells.
High expression of IL-13Ra2 is significantly associated with the growth and metastasis of glioma cells via the Scr/PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies)/mTOR (show FRAP1 Antibodies) pathway.
A negative correlation between IL-13Ra2 and IL-13 (show IL13 Antibodies) was found during early infection of human schistosomiasis, suggesting an increase in cytokine in early fibrosis.
Data indicate single-chain antibody (scFv47) as a highly selective interleukin 13 receptor subunit alpha 2 (IL13Ralpha2) targeting agent.
IL13Ralpha2 knockdown and IL-13 (show IL13 Antibodies) treatment cooperatively upregulated the metastasis suppressor tumor protein 63 (TP63 (show TP63 Antibodies)) in a STAT6 (show STAT6 Antibodies)-dependent manner.
Expression of CXCR3 (show CXCR3 Antibodies) in fibroblasts is associated with the expression of IL-13Ralpha2.
Study presents evidence that PNR (show NR2E3 Antibodies) could promote ERalpha (show ESR1 Antibodies)-negative breast cancer metastasis through activation of IL-13Ralpha2-mediated signaling pathway.
Results suggest that the physical interaction between the cytoplasmic domains of IL-13Ralpha2 and IL-4Ralpha regulates IL-4 (show IL4 Antibodies) signaling through the IL-4Ralpha-IL-13Ralpha1 receptor complex.
In cytotoxicity assays, CAR T cells killed CAR T cells killed IL13Ra1 (show IL13RA1 Antibodies)- and/or IL13Ra2-positive cells in contrast to IL13Ra1 (show IL13RA1 Antibodies)- and IL13Ra2-negative controls
endogenously expressed IL-13Ralpha2 does not activate any unique IL-13 (show IL13 Antibodies)-mediated gene expression patterns, confirming its role as a decoy receptor for IL-13 (show IL13 Antibodies) signaling.
Upon lipopolysaccharide stimulation, macrophage Raw 264.7 cells showed elevated IL-13R-alpha-2 expression via immunofluorescence staining and increased MRI (show C7ORF49 Antibodies) probe binding via built-in TAMRA fluorescence imaging. for the first time, IL-13R-alpha-2 was investigated as a unique biomarker in the context of osteomyelitis.
overexpression of IL-13Ra2 inhibits the IL-13 (show IL13 Antibodies) induction of fibrotic markers in vitro and inhibits bleomycin-induced pulmonary fibrosis.
IL-13 (show IL13 Antibodies) contributes to the development of pulmonary hypertension via an IL-13receptor alpha2-arginase 2 (show ARG2 Antibodies)-dependent pathway.
Colitis and intestinal inflammation in IL10 (show IL10 Antibodies)(-/-) mice results from IL-13Ralpha2-mediated attenuation of IL-13 (show IL13 Antibodies) activity.
These results are consistent with a phenotype of enhanced interleukin-13 (IL-13 (show IL13 Antibodies))responsiveness and demonstrate a role for endogenous IL-13 (show IL13 Antibodies) and IL-13 (show IL13 Antibodies) alpha2 receptor in regulating immune responses in wild-type mice.
IL-13 (show IL13 Antibodies) receptor alpha2
by suppressing IFN-gamma (show IFNG Antibodies) and up-regulating the decoy IL-13 (show IL13 Antibodies) receptor, P-selectin (show SELP Antibodies) dramatically inhibits the pathologic tissue remodeling that results from chronic type 2 cytokine-mediated hepatic inflammation
TGF-beta1 (show TGFB1 Antibodies) production and fibrosis require IL-13 (show IL13 Antibodies) signaling through the IL-13alpha2 receptor
IL-10 (show IL10 Antibodies) and IL-13Ralpha2 are both required to control chronic Th2-driven pathological responses.
The protein encoded by this gene is closely related to Il13RA1, a subuint of the interleukin 13 receptor complex. This protein binds IL13 with high affinity, but lacks cytoplasmic domain, and does not appear to function as a signal mediator. It is reported to play a role in the internalization of IL13.
interleukin-13 receptor alpha 2
, interleukin-13 receptor subunit alpha-2
, IL-13 receptor alpha 2
, interleukin 13 receptor, alpha 2
, interleukin-13 receptor subunit alpha-2-like
, IL-13 receptor subunit alpha-2
, IL-13R subunit alpha-2
, cancer/testis antigen 19
, interleukin 13 binding protein
, interleukin 13 receptor alpha 2 chain
, interleukin-13-binding protein
, interleukin 13 receptor alpha chain 2