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IL29 encodes a cytokine distantly related to type I interferons and the IL-10 family. Additionally we are shipping IL29 Kits (29) and IL29 Proteins (29) and many more products for this protein.
Showing 10 out of 58 products:
Human Polyclonal IL29 Primary Antibody for EIA, IHC (p) - ABIN357175
Kotenko, Gallagher, Baurin, Lewis-Antes, Shen, Shah, Langer, Sheikh, Dickensheets, Donnelly: IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex. in Nature immunology 2002
Show all 2 references for ABIN357175
this study shows that serum levels of IL-29 play a role in the pathogenesis of Hashimoto's thyroiditis in Turkey
serum levels of IL-32 (show IL32 Antibodies) and TNF-alpha (show TNF Antibodies) may be diagnostic markers, and serum IL-29 levels may be associated with good prognosis in patients with gastric cancer
Serum levels of IL-29 and IFN-gamma (show IFNG Antibodies) are predictive of relapse outcomes after hepatitis C treatment.
IL-29 selectively induces CXCR3A-binding chemokines (CXCL9 (show CXCL9 Antibodies), CXCL10 (show CXCL10 Antibodies), CXCL11 (show CXCL11 Antibodies)) in skin cells. Murine IL-29 counterpart induces skin T-cell infiltration and inflammation in mice.
activation of TLR7 upregulated the expression levels of IFN-lambda1 and MMP-9 were increased by ~3 fold, whereas other genes (p53, PTEN, TIMP-1) were upregulated by ~2 fold, and VEGF was marginally upregulated after 10 min.
IL-29 directly induces RANKL (show TNFSF11 Antibodies) expression in rheumatoid arthritis-fibroblasts like synoviocytes via MAPK (show MAPK1 Antibodies) signaling pathway.
IFN-lambda-1 and interferon-gamma (show IFNG Antibodies) levels in systemic sclerosis patients were significantly higher than those in healthy individuals.
this study failed to prove any significant association between polymorphisms in IL29 gene rs30461 or IL10 (show IL10 Antibodies) gene (-1082, -819 and -592) or cytokine haplotype and either response to therapy or severity of HCV infection in children.
IL-29 can aggravate LPS/TLR4 (show TLR4 Antibodies)-mediated inflammation.
NS of severe fever with thrombocytopenia syndrome virus inhibited the activity of IFN-alpha1 (show IFNA1 Antibodies), IFN-beta (show IFNB1 Antibodies), IFN-lambda1 and IFN-lambda2 (show IL28A Antibodies) through inhibition of STAT1 (show STAT1 Antibodies) phosphorylation.
We here report the molecular cloning, expression and antiviral activity of porcine IL-29
This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 28B (IL28B) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).
, cytokine Zcyto21
, interferon lambda-1
, interleukin 29 (interferon, lambda 1)
, interleukin 28B
, interferon lamda 1