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IL29 encodes a cytokine distantly related to type I interferons and the IL-10 family. Additionally we are shipping IL29 Antibodies (58) and IL29 Kits (30) and many more products for this protein.
Showing 10 out of 25 products:
Human IL29 Protein expressed in HEK-293 Cells - ABIN2181309
Sheppard, Kindsvogel, Xu, Henderson, Schlutsmeyer, Whitmore, Kuestner, Garrigues, Birks, Roraback, Ostrander, Dong, Shin, Presnell, Fox, Haldeman, Cooper, Taft, Gilbert, Grant, Tackett, Krivan et al.: IL-28, IL-29 and their class II cytokine receptor IL-28R. ... in Nature immunology 2002
Show all 3 references for ABIN2181309
Human IL29 Protein expressed in Human Cells - ABIN2005173
Kotenko, Gallagher, Baurin, Lewis-Antes, Shen, Shah, Langer, Sheikh, Dickensheets, Donnelly: IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex. in Nature immunology 2002
Show all 2 references for ABIN2005173
Serum levels of IL-29 and IFN-gamma (show IFNG Proteins) are predictive of relapse outcomes after hepatitis C treatment.
IL-29 selectively induces CXCR3A-binding chemokines (CXCL9 (show CXCL9 Proteins), CXCL10 (show CXCL10 Proteins), CXCL11 (show CXCL11 Proteins)) in skin cells. Murine IL-29 counterpart induces skin T-cell infiltration and inflammation in mice.
activation of TLR7 upregulated the expression levels of IFN-lambda1 and MMP-9 were increased by ~3 fold, whereas other genes (p53, PTEN, TIMP-1) were upregulated by ~2 fold, and VEGF was marginally upregulated after 10 min.
IL-29 directly induces RANKL (show TNFSF11 Proteins) expression in rheumatoid arthritis-fibroblasts like synoviocytes via MAPK (show MAPK1 Proteins) signaling pathway.
IFN-lambda-1 and interferon-gamma (show IFNG Proteins) levels in systemic sclerosis patients were significantly higher than those in healthy individuals.
this study failed to prove any significant association between polymorphisms in IL29 gene rs30461 or IL10 (show IL10 Proteins) gene (-1082, -819 and -592) or cytokine haplotype and either response to therapy or severity of HCV infection in children.
IL-29 can aggravate LPS/TLR4 (show TLR4 Proteins)-mediated inflammation.
NS of severe fever with thrombocytopenia syndrome virus inhibited the activity of IFN-alpha1 (show IFNA1 Proteins), IFN-beta (show IFNB1 Proteins), IFN-lambda1 and IFN-lambda2 (show IL28A Proteins) through inhibition of STAT1 (show STAT1 Proteins) phosphorylation.
the role of IFN-lambda in IDO (show IDO1 Proteins) regulation was investigated after influenza infection of respiratory epithelial cells.
Data suggest that naturally occurring iDVGs (immunostimulatory defective viral genomes) trigger robust host antiviral/innate immunity responses including/requiring up-regulation of IFNL1 and IFNB1 (interferon beta 1 (show IFNB1 Proteins)) in respiratory mucosa.
We here report the molecular cloning, expression and antiviral activity of porcine IL-29
This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 28B (IL28B) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).
, cytokine Zcyto21
, interferon lambda-1
, interleukin 29 (interferon, lambda 1)
, interleukin 28B
, interferon lamda 1