IL29 Protein (AA 1-200)
-
- Target See all IL29 Proteins
- IL29 (Interleukin 29 (IL29))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-200
-
Origin
- Human
-
Source
- HEK-293 Cells
- Sequence
- Met1-Thr200
- Characteristics
- A DNA sequence encoding the Human IL-29 Protein(Q8IU54)(1-200)was expressed with a polyhistidine tag at the N-terminus.
- Purity
- >95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- <1.0 EU per μg of the protein as determined by the LAL method.
- Top Product
- Discover our top product IL29 Protein
-
Interleukin 29 (IL29) (AA 22-200) protein (His tag)
IL29 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Interleukin 29 (IL29) (AA 20-200) protein (His tag)Crystallography grade IL29 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4., 5 % trehalose, 5 % mannitol, 0.01 % tween-80.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
-
- Target
- IL29 (Interleukin 29 (IL29))
- Alternative Name
- IL-29 (IL29 Products)
- Synonyms
- IL-29 Protein, IL29 Protein, interferon lambda 1 Protein, interferon lambda-1 Protein, interleukin 29 (interferon, lambda 1) Protein, IFNL1 Protein, LOC612539 Protein, IL29 Protein
- Background
-
Background: Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.
Synonym: Interferon lambda-1,IFN-lambda-1,ytokine Zcyto21,Interleukin-29,IL29,IFNL1,ZCYTO21
- Molecular Weight
- 22 kDa
- UniProt
- Q8IU54
-
