anti-Interleukin 31 (IL31) Antibodies

IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. Additionally we are shipping Interleukin 31 Kits (52) and Interleukin 31 Proteins (41) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
IL31 386653 Q6EBC2
IL31 76399 Q6EAL8
IL31 690028  
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Top anti-Interleukin 31 Antibodies at antibodies-online.com

Showing 10 out of 112 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, FACS, IHC (p), WB Flow cytometric analysis of WiDr cells using IL31 Antibody (N-term) Cat.-No AP52198PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Formalin-fixed and paraffin-embedded human testis tissue reacted with IL31 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000;  TMB staining;  Read the data in MicroplateReader by 450 Formalin-fixed and paraffin embedded human kidney labeled with Rabbit Anti-IL-31 Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$295.90
Details
Human Rabbit Un-conjugated EIA, WB   0.1 mg Log in to see 12 to 15 Days
$375.38
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of IL31 Antibody (N-term) (ABIN653336) in mouse spleen tissue lysates (35 µg/lane). IL31 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human testis tissue reacted with IL31 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Mouse Rabbit Un-conjugated EIA, IHC (p), WB   0.1 mg Log in to see 12 to 15 Days
$375.38
Details
Human Rabbit Un-conjugated IHC (p), WB Human Thymus (formalin-fixed, paraffin-embedded) stained with IL31 antibody ABIN214501 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 7 to 9 Days
$451.00
Details
Mouse Rabbit Un-conjugated IF (p), IHC (p), WB Antigen: 2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Rabbit Anti-Goat IgG at 1: 5000;  TMB staining Read the data in Microplate Reader by 450nm. 100 μL Log in to see 14 to 21 Days
$295.90
Details
Human Mouse Un-conjugated BCA 100 μg Log in to see 10 to 12 Days
$244.59
Details
Mouse Rat Un-conjugated BCA 100 μg Log in to see 10 to 12 Days
$244.59
Details

IL31 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Interleukin 31 Antibodies

  1. Human Polyclonal IL31 Primary Antibody for ELISA, WB - ABIN2475000 : Castellani, Salini, Frydas, Donelan, Madhappan, Petrarca, Vecchiet, Falasca, Neri, Tete: Interleukin-31: a new cytokine involved in inflammation of the skin. in International journal of immunopathology and pharmacology 2006 (PubMed)

More Antibodies against Interleukin 31 Interaction Partners

Human Interleukin 31 (IL31) interaction partners

  1. The first demonstration of the involvement of the IL-31/IL-31R axis in cancer came from studies in patients with mycosis fungoides/Sezary syndrome, the most frequent, cutaneous T cell lymphoma. Tumor cells were shown to produce IL-31, whose serum levels correlated with pruritus intensity.

  2. IL31 and its receptor, IL31RA (show IL31RA Antibodies), are highly expressed in various human and mouse cancer cell lines, as well as in tumor specimens from cancer patients. MC38 murine colon carcinoma cells depleted of IL31 exhibit an increase in invasive and migratory properties in vitro.

  3. this study shows that IL-31 may be involved in the pathogenesis of asthma and rhinitis; dust mite and mugwort allergy could increase it significantly

  4. While serum TSLP (show TSLP Antibodies) levels were unaffected by concomitant allergies and atopic comorbidities, serum levels of IL-31, IL-33 (show IL33 Antibodies) and sST2 (show SSTR2 Antibodies) were affected to a small extent. We found a positive correlation between TSLP (show TSLP Antibodies), IL-31 and IL-33 (show IL33 Antibodies), and an inverse relationship between IL-33 (show IL33 Antibodies) and sST2 (show SSTR2 Antibodies)

  5. Suggest that IL-31 gene may play a role in the development of systemic lupus erythematosus.

  6. High IL31 expression is associated with Endometrial Cancer.

  7. In a CML (show BCR Antibodies) patient with pruritus receiving imatinib mesylate, IL-31 and IL-33 (show IL33 Antibodies) serum levels were significantly higher than controls. Imatinib could cause keratinocyte injury, the release of IL-33 (show IL33 Antibodies), and the consequent interaction with its receptor on mast cells, inducing IL-31 secretion. The IL-31/IL-33 (show IL33 Antibodies) axis may be involved in the pathogenesis of skin side effects related to imatinib mesylate treatment.

  8. Distinct polymorphic variants of the IL-31 gene may be involved in the patho-genesis of mastocytosis, and IL-31 may be involved in the induction of pruritus in patients with mastocytosis.

  9. Serum/pleural fluid IL-31 levels are elevated in tuberculous pleural effusion.

  10. both SCF (show KITLG Antibodies) and IL-31 play an important role in mediating inflammation and enhancing severity of atopic asthma.

Mouse (Murine) Interleukin 31 (IL31) interaction partners

  1. IL31 and its receptor, IL31RA (show IL31RA Antibodies), are highly expressed in various human and mouse cancer cell lines, as well as in tumor specimens from cancer patients. MC38 murine colon carcinoma cells depleted of IL31 exhibit an increase in invasive and migratory properties in vitro.

  2. Oncostatin M (show OSM Antibodies) and interleukin-31: Cytokines, receptors, signal transduction and physiology.

  3. IL-31 upregulates IL-31RA (show IL31RA Antibodies) expression in DRG neuron cell bodies, and cutaneous-injected IL-31-induced itching is enhanced by DRG IL-31RA (show IL31RA Antibodies) expression in mice

  4. our results suggest a functional cooperation between NFAT1 (show NFAT1 Antibodies) and JunB (show JUNB Antibodies) in mediating IL-31 gene expression in CD4 (show CD4 Antibodies)(+) T cells

  5. Data not only illustrate various functions that cysteines perform during IL-31 biosynthesis and secretion, but also highlight their potential roles in cytokine effector functions.

  6. IL-31 may be involved in promoting the dermatitis and epithelial responses that characterize allergic and non-allergic diseases

  7. IL-31 interaction with IL-31 receptor (IL-31R) is identified in an acute model of T helper cell type 2 inflammation in the lung.

  8. these data provide the first evidence of a function for IL-31-IL-31R interactions in limiting the magnitude of type 2 inflammatory responses within the intestine.

Interleukin 31 (IL31) Antigen Profile

Protein Summary

IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma (Dillon et al., 2004

Gene names and symbols associated with anti-Interleukin 31 (IL31) Antibodies

  • interleukin 31 (IL31) antibody
  • interleukin 31 (Il31) antibody
  • 1700013B14Rik antibody
  • IL-31 antibody
  • IL31 antibody

Protein level used designations for anti-Interleukin 31 (IL31) Antibodies

interleukin 31 , interleukin-31 , IL-31

GENE ID SPECIES
701655 Macaca mulatta
744097 Pan troglodytes
100144624 Sus scrofa
386653 Homo sapiens
76399 Mus musculus
690028 Rattus norvegicus
100302725 Canis lupus familiaris
101903065 Bos taurus
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